☆ 4.7 Editorial Material

New insights into the utility of omalizumab

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2019)

Journal

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Volume 143, Issue 3, Pages 923-+

Publisher

MOSBY-ELSEVIER

DOI: 10.1016/j.jaci.2019.01.016

Keywords

IgE; Fc epsilon RI alpha; mAb; biologic therapy; allergy; antiviral immunity; asthma; chronic urticaria; food allergy; immunotherapy

Categories

Allergy Immunology

Funding

Culverhouse family fund
[K23AI125785]
[R01HL116849]

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Review Allergy

Patient-centered digital biomarkers for allergic respiratory diseases and asthma: The ARIA-EAACI approach - ARIA-EAACI Task Force Report

Jean Bousquet, Mohamed H. Shamji, Josep M. Anto, Holger J. Schuenemann, G. Walter Canonica, Marek Jutel, Stefano Del Giacco, Torsten Zuberbier, Oliver Pfaar, Joao A. Fonseca, Bernardo Sousa-Pinto, Ludger Klimek, Wienczyslawa Czarlewski, Anna Bedbrook, Rita Amaral, Ignacio J. Ansotegui, Sinthia Bosnic-Anticevich, Fulvio Braido, Claudia Chaves Loureiro, Bilun Gemicioglu, Tari Haahtela, Marek Kulus, Piotr Kuna, Maciej Kupczyk, Paolo M. Matricardi, Frederico S. Regateiro, Boleslaw Samolinski, Mikhail Sofiev, Sanna Toppila-Salmi, Arunas Valiulis, Maria Teresa Ventura, Cristina Barbara, Karl C. Bergmann, Michael Bewick, Hubert Blain, Matteo Bonini, Louis-Philippe Boulet, Rodolphe Bourret, Guy Brusselle, Luisa Brussino, Roland Buhl, Victoria Cardona, Thomas Casale, Lorenzo Cecchi, Denis Charpin, Ivan Cherrez-Ojeda, Derek K. Chu, Cemal Cingi, Elisio M. Costa, Alvaro A. Cruz, Philippe Devillier, Stephanie Dramburg, Wytske J. Fokkens, Maia Gotua, Enrico Heffler, Zhanat Ispayeva, Juan Carlos Ivancevich, Guy Joos, Igor Kaidashev, Helga Kraxner, Violeta Kvedariene, Desiree E. Larenas-Linnemann, Daniel Laune, Olga Lourenco, Renaud Louis, Mika Makela, Michael Makris, Marcus Maurer, Erik Melen, Yann Micheli, Mario Morais-Almeida, Joaquim Mullol, Marek Niedoszytko, Robyn O'Hehir, Yoshitaka Okamoto, Heidi Olze, Nikolaos G. Papadopoulos, Alberto Papi, Vincenzo Patella, Benoit Petre, Nhan Pham-Thi, Francesca Puggioni, Santiago Quirce, Nicolas Roche, Philip W. Rouadi, Ana Sa-Sousa, Hironori Sagara, Joaquin Sastre, Nicola Scichilone, Aziz Sheikh, Milan Sova, Charlotte Suppli Ulrik, Luis Taborda-Barata, Ana Todo-Bom, Maria J. Torres, Ioanna Tsiligianni, Omar S. Usmani, Erkka Valovirta, Tuula Vasankari, Rafael Jose Vieira, Dana Wallace, Susan Waserman, Mihaela Zidarn, Arzu Yorgancioglu, Luo Zhang, Tomas Chivato, Markus Ollert

Summary: Biomarkers, especially digital biomarkers, are urgently needed in the diagnosis, treatment and follow-up of patients with rhinitis and/or asthma. The lack of validated biomarkers in primary care poses a challenge, but the digital transformation of health care holds potential in improving allergy management. The Allergic Rhinitis and its Impact on Asthma (ARIA) and the European Academy of Allergy and Clinical Immunology (EAACI) have developed patient-reported outcome measures (PROMs) as digital biomarkers for rhinitis and asthma, including control biomarkers and quality-of-life biomarkers.

ALLERGY (2023)

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Editorial Material Allergy

Is it time to set the alarmins as potential targets in food allergy?

Amber N. Pepper, Thomas B. Casale

ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY (2023)

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Review Otorhinolaryngology

International consensus statement on allergy and rhinology: Allergic rhinitis-2023

Sarah K. Wise, Cecelia Damask, Lauren T. Roland, Charles Ebert, Joshua M. Levy, Sandra Lin, Amber Luong, Kenneth Rodriguez, Ahmad R. Sedaghat, Elina Toskala, Jennifer Villwock, Baharudin Abdullah, Cezmi Akdis, Jeremiah A. Alt, Ignacio J. Ansotegui, Antoine Azar, Fuad Baroody, Michael S. Benninger, Jonathan Bernstein, Christopher Brook, Raewyn Campbell, Thomas Casale, Mohamad Chaaban, Fook Tim Chew, Jeffrey Chambliss, Antonella Cianferoni, Adnan Custovic, Elizabeth Mahoney Davis, John M. DelGaudiomd, Anne K. Ellis, Carrie Flanagan, Wytske J. Fokkens, Christine Franzese, Matthew Greenhawt, Amarbir Gill, Ashleigh Halderman, Jens M. Hohlfeld, Cristoforo Incorvaia, Stephanie A. Joe, Shyam Joshi, Merin Elizabeth Kuruvilla, Jean Kim, Adam M. Klein, Helene J. Krouse, Edward C. Kuan, David Lang, Desiree Larenas-Linnemann, Adrienne M. Laury, Matt Lechner, Stella E. Lee, Victoria S. Lee, Patricia Loftus, Sonya Marcus, Haidy Marzouk, Jose Mattos, Edward McCoul, Erik Melen, James W. Mims, Joaquim Mullol, Jayakar V. Nayak, John Oppenheimer, Richard R. Orlandi, Katie Phillips, Michael Platt, Murugappan Ramanathan, Mallory Raymond, Chae-Seo Rhee, Sietze Reitsma, Matthew Ryan, Joaquin Sastre, Rodney J. Schlosser, Theodore A. Schuman, Marcus S. Shaker, Aziz Sheikh, Kristine A. Smith, Michael B. Soyka, Masayoshi Takashima, Monica Tang, Pongsakorn Tantilipikorn, Malcolm B. Taw, Jody Tversky, Matthew A. Tyler, Maria C. Veling, Dana Wallace, De Yun Wang, Andrew White, Luo Zhang

Summary: The ICAR-Allergic Rhinitis 2023 update expands on the 2018 International Consensus Statement on Allergy and Rhinology, including 144 topics on allergic rhinitis. The update employed evidence-based review methodology and peer consensus for each topic. It provides comprehensive evaluation, evidence, and recommendations for patient evaluation and treatment of allergic rhinitis.

INTERNATIONAL FORUM OF ALLERGY & RHINOLOGY (2023)

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Article Allergy

Criteria used by health professionals on the selection of allergen immunotherapy in real clinical practice: Methodology br

Davide Caimmi, Pablo Rodriguez del Rio, Pilar Rico, Carmen Vidal, Carmen Moreno, Thomas B. Casale, Pascal Demoly, Moises A. Calderdon

Summary: Allergen immunotherapy (AIT) is the only etiological therapy for respiratory allergic diseases. The CHOICE-Global Survey aims to study the key parameters that drive the prescription of AIT by doctors and the acceptance of AIT by patients. This survey will provide academic information on the drivers of AIT prescription in real-life practice, improving understanding of this therapy.

WORLD ALLERGY ORGANIZATION JOURNAL (2023)

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Article Allergy

Dupilumab Efficacy in Patients with Uncontrolled Moderate-to-Severe Type 2 Asthma Regardless of Perennial Aeroallergen Sensitization

Jonathan Corren, David J. Jackson, Thomas B. Casale, Larry Borish, Klaus F. Rabe, William W. Busse, Jorge F. Maspero, Daniel J. Jackson, Nadia Daizadeh, Arman Altincatal, Amr Radwan, Angela Khodzhayev, Michel Djandji, Juby A. Jacob-Nara, Paul J. Rowe, Yamo Deniz

Summary: In this study, Dupilumab demonstrated good efficacy by reducing asthma exacerbations and improving lung function in patients with uncontrolled, moderate-to-severe T2 asthma. Furthermore, Dupilumab showed similar effects in improving clinical outcomes and reducing biomarkers levels regardless of allergen sensitization status or number.

JOURNAL OF ASTHMA AND ALLERGY (2023)

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Article Allergy

CHOICE international survey: Clusters of allergen immunotherapy prescription from French and Spanish cohorts

Pablo Rodriguez del Rio, Davide Caimmi, Pilar Rico Nieto, Carmen Vidal, Carmen Moreno, Maria Teresa Gonzalez-Fernandez, Margarita Tomas-Perez, Ana Beristain, Isa Bosse, Hoai Bich Trinh, Thomas B. Casale, Pascal Demoly, Moises A. Calderon, on behalf of the C. H. O. I. C. E. Survey Team CHOICE Survey Team

Summary: This study investigated the drivers of prescription for allergen immunotherapy (AIT) for respiratory allergic diseases. The results showed that there are multiple drivers for AIT prescription, including the characteristics of doctors and patients as well as the disease characteristics.

WORLD ALLERGY ORGANIZATION JOURNAL (2023)

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Review Allergy

Hot topics in allergen immunotherapy, 2023: Current status and future perspective

Magdalena Zemelka-Wiacek, Ioana Agache, Cezmi A. Akdis, Muebeccel Akdis, Thomas B. Casale, Stephanie Dramburg, Karina Jahnz-Rozyk, Anna Kosowska, Paolo M. Matricardi, Oliver Pfaar, Mohamed H. Shamji, Marek Jutel

Summary: The importance of allergen immunotherapy (AIT) lies in its ability to improve clinical outcomes and quality of life while reducing long-term costs. AIT induces allergen tolerance through various mechanisms, including changes in immune responses, suppression of allergen-specific IgE, and modulation of cell activation. Recent advancements in biomarkers, molecular diagnostics, and mobile health applications have the potential to enhance AIT efficacy and compliance. Additionally, artificial intelligence can aid in data interpretation and prediction of patient responses. Novel AIT preparations and advancements in clinical trial models contribute to the growth and development of AIT.

ALLERGY (2023)

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