A high-throughput drug screen identifies auranofin as a potential sensitizer of cisplatin in small cell lung cancer

Targeting Breast Cancer Stem Cell State Equilibrium through Modulation of Redox Signaling

(2018) Ming Luo et al.   Cell Metabolism

Inhibition of Thioredoxin/Thioredoxin Reductase Induces Synthetic Lethality in Lung Cancers with Compromised Glutathione Homeostasis

(2018) Xiang Yan et al.   CANCER RESEARCH

Auranofin/Vitamin C: A Novel Drug Combination Targeting Triple-Negative Breast Cancer

(2018) Elie Hatem et al.   JNCI-Journal of the National Cancer Institute

Allosteric cross-talk in chromatin can mediate drug-drug synergy

(2017) Zenita Adhireksan et al.   Nature Communications

Combination treatment of RAD001 and BEZ235 exhibits synergistic antitumor activity via down-regulation of p-4E-BP1/Mcl-1 in small cell lung cancer

(2017) Bo Hong et al.   Oncotarget

Drug Combination Studies and Their Synergy Quantification Using the Chou–Talalay Method—Letter

(2015) John C. Ashton   CANCER RESEARCH

Small Cell Lung Cancer: Will Recent Progress Lead to Improved Outcomes?

(2015) M. C. Pietanza et al.   CLINICAL CANCER RESEARCH

Cucurbitacin B induces DNA damage and autophagy mediated by reactive oxygen species (ROS) in MCF-7 breast cancer cells

(2015) Guowen Ren et al.   Journal of Natural Medicines

Transformation from non-small-cell lung cancer to small-cell lung cancer: molecular drivers and cells of origin

(2015) Matthew G Oser et al.   LANCET ONCOLOGY

Auranofin induces apoptosis by ROS-mediated ER stress and mitochondrial dysfunction and displayed synergistic lethality with piperlongumine in gastric cancer

(2015) Peng Zou et al.   Oncotarget

Epidemiology of lung cancer in China

(2015) Wanqing Chen et al.   Thoracic Cancer

Auranofin Induces Lethal Oxidative and Endoplasmic Reticulum Stress and Exerts Potent Preclinical Activity against Chronic Lymphocytic Leukemia

(2014) W. Fiskus et al.   CANCER RESEARCH

Enhancement of Auranofin-Induced Apoptosis in MCF-7 Human Breast Cells by Selenocystine, a Synergistic Inhibitor of Thioredoxin Reductase

(2013) Chaoran Liu et al.   PLoS One

Vinca alkaloids cause aberrant ROS-mediated JNK activation, Mcl-1 downregulation, DNA damage, mitochondrial dysfunction, and apoptosis in lung adenocarcinoma cells

(2012) Wei-Hsin Chiu et al.   BIOCHEMICAL PHARMACOLOGY

A high-throughput drug screen for Entamoeba histolytica identifies a new lead and target

(2012) Anjan Debnath et al.   NATURE MEDICINE

Selective targeting of breast cancer cells through ROS-mediated mechanisms potentiates the lethality of paclitaxel by a novel diterpene, gelomulide K

(2011) Juan-Cheng Yang et al.   FREE RADICAL BIOLOGY AND MEDICINE

N′1,N′3-Dimethyl-N′1,N′3-bis(phenylcarbonothioyl) Propanedihydrazide (Elesclomol) Selectively Kills Cisplatin Resistant Lung Cancer Cells through Reactive Oxygen Species (ROS)

(2009) Medhi Wangpaichitr et al.   Cancers