A Novel Rare Missense Variation of the NOD2 Gene: Evidencesof Implication in Crohn’s Disease

Relation between NOD2 genotype and changes in innate signaling in Crohn’s disease on mRNA and miRNA levels

(2017) Yun Chen et al.   npj Genomic Medicine

Crystal structure of NOD2 and its implications in human disease

(2016) Sakiko Maekawa et al.   Nature Communications

Novel Missense Mutation in the NOD2 Gene in a Patient with Early Onset Ulcerative Colitis: Causal or Chance Association?

(2014) Martina Girardelli et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

A general framework for estimating the relative pathogenicity of human genetic variants

(2014) Martin Kircher et al.   NATURE GENETICS

Epidemiology of inflammatory bowel diseases: New insights from a French population-based registry (EPIMAD)

(2012) Corinne Gower-Rousseau et al.   DIGESTIVE AND LIVER DISEASE

Etiology of inflammatory bowel disease: A unified hypothesis

(2012) Xiaofa Qin   WORLD JOURNAL OF GASTROENTEROLOGY

Variants of NOD1 and NOD2 genes display opposite associations with familial risk of crohnʼs disease and anti-saccharomyces cerevisiae antibody levels

(2011) Francis Vasseur et al.   INFLAMMATORY BOWEL DISEASES

Deep resequencing of GWAS loci identifies independent rare variants associated with inflammatory bowel disease

(2011) Manuel A Rivas et al.   NATURE GENETICS

Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

(2010) Andre Franke et al.   NATURE GENETICS

A method and server for predicting damaging missense mutations

(2010) Ivan A Adzhubei et al.   NATURE METHODS