Clonal Hematopoiesis with Oncogenic Potential (CHOP): Separation from CHIP and Roads to AML
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Title
Clonal Hematopoiesis with Oncogenic Potential (CHOP): Separation from CHIP and Roads to AML
Authors
Keywords
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Journal
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 20, Issue 3, Pages 789
Publisher
MDPI AG
Online
2019-02-13
DOI
10.3390/ijms20030789
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Note: Only part of the references are listed.- Consequences of mutant TET2 on clonality and subclonal hierarchy
- (2018) Cassandra M. Hirsch et al. LEUKEMIA
- Molecular Minimal Residual Disease in Acute Myeloid Leukemia
- (2018) Mojca Jongen-Lavrencic et al. NEW ENGLAND JOURNAL OF MEDICINE
- Idiopathic Cytopenia of Uncertain Significance, Idiopathic Dysplasia of Unknown Significance, Clonal Hematopoiesis with Indeterminate Potential, and Clonal Cytopenia of Unknown Significance: Diagnostic Criteria, Separation from Myelodysplastic Syndromes, and Clinical Implications
- (2018) Peter Valent PATHOBIOLOGY
- Somatic Mutations in Philadelphia Chromosome-Negative Myeloproliferative Neoplasms
- (2018) Sérgio Ferreira Cristina et al. SEMINARS IN HEMATOLOGY
- Poor Prognostic Implication of ASXL1 Mutations in Korean Patients With Chronic Myelomonocytic Leukemia
- (2018) Hyun-Young Kim et al. Annals of Laboratory Medicine
- Genomics of Acute Myeloid Leukemia Diagnosis and Pathways
- (2017) Lars Bullinger et al. JOURNAL OF CLINICAL ONCOLOGY
- Clonal Hematopoiesis Associated With Adverse Outcomes After Autologous Stem-Cell Transplantation for Lymphoma
- (2017) Christopher J. Gibson et al. JOURNAL OF CLINICAL ONCOLOGY
- Preleukaemic clonal haemopoiesis and risk of therapy-related myeloid neoplasms: a case-control study
- (2017) Koichi Takahashi et al. LANCET ONCOLOGY
- Genomic determinants of chronic myelomonocytic leukemia
- (2017) B J Patel et al. LEUKEMIA
- Nilotinib-induced vasculopathy: identification of vascular endothelial cells as a primary target site
- (2017) E Hadzijusufovic et al. LEUKEMIA
- Clonal Hematopoiesis and Risk of Atherosclerotic Cardiovascular Disease
- (2017) Siddhartha Jaiswal et al. NEW ENGLAND JOURNAL OF MEDICINE
- RUNX1 deficiency (familial platelet disorder with predisposition to myeloid leukemia, FPDMM)
- (2017) Brigitte Schlegelberger et al. SEMINARS IN HEMATOLOGY
- Familial CEBPA -mutated acute myeloid leukemia
- (2017) Kiran Tawana et al. SEMINARS IN HEMATOLOGY
- ASXL1 frameshift mutations drive inferior outcomes in CMML without negative impact in MDS
- (2017) David A Sallman et al. Blood Cancer Journal
- Proposed minimal diagnostic criteria for myelodysplastic syndromes (MDS) and potential pre-MDS conditions
- (2017) Peter Valent et al. Oncotarget
- Evolution of Premalignant Disease
- (2017) Kit Curtius et al. Cold Spring Harbor Perspectives in Medicine
- Familial MPN Predisposition
- (2017) Tsewang Tashi et al. Current Hematologic Malignancy Reports
- Proposed Terminology and Classification of Pre-Malignant Neoplastic Conditions: A Consensus Proposal
- (2017) Peter Valent et al. EBioMedicine
- Emerging treatments for classical myeloproliferative neoplasms
- (2016) Alessandro M. Vannucchi et al. BLOOD
- Time-dependent changes in mortality and transformation risk in MDS
- (2016) Michael Pfeilstöcker et al. BLOOD
- Germ line variants predispose to both JAK2 V617F clonal hematopoiesis and myeloproliferative neoplasms
- (2016) D. A. Hinds et al. BLOOD
- Integrating clinical features and genetic lesions in the risk assessment of patients with chronic myelomonocytic leukemia
- (2016) C. Elena et al. BLOOD
- The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia
- (2016) D. A. Arber et al. BLOOD
- Application of an NGS-based 28-gene panel in myeloproliferative neoplasms reveals distinct mutation patterns in essential thrombocythaemia, primary myelofibrosis and polycythaemia vera
- (2016) Sabit Delic et al. BRITISH JOURNAL OF HAEMATOLOGY
- Prognostic significance ofASXL1mutations in myelodysplastic syndromes and chronic myelomonocytic leukemia: A meta-analysis
- (2016) Yun Lin et al. Hematology
- Subtype-specific patterns of molecular mutations in acute myeloid leukemia
- (2016) D Rose et al. LEUKEMIA
- Somatic PHF6 mutations in 1760 cases with various myeloid neoplasms
- (2016) T Mori et al. LEUKEMIA
- Dynamics of clonal evolution in myelodysplastic syndromes
- (2016) Hideki Makishima et al. NATURE GENETICS
- Efficacy and Safety of Midostaurin in Advanced Systemic Mastocytosis
- (2016) Jason Gotlib et al. NEW ENGLAND JOURNAL OF MEDICINE
- Genomic Classification and Prognosis in Acute Myeloid Leukemia
- (2016) Elli Papaemmanuil et al. NEW ENGLAND JOURNAL OF MEDICINE
- Targeted deep sequencing improves outcome stratification in chronic myelomonocytic leukemia with low risk cytogenetic features
- (2016) Laura Palomo et al. Oncotarget
- Germline mutations of KIT in gastrointestinal stromal tumor (GIST) and mastocytosis
- (2016) Hengning Ke et al. Cell and Bioscience
- Blast transformation in chronic myelomonocytic leukemia: Risk factors, genetic features, survival, and treatment outcome
- (2015) Mrinal M. Patnaik et al. AMERICAN JOURNAL OF HEMATOLOGY
- Targeted sequencing identifies patients with preclinical MDS at high risk of disease progression
- (2015) C. A. Cargo et al. BLOOD
- Rapid expansion of preexisting nonleukemic hematopoietic clones frequently follows induction therapy for de novo AML
- (2015) T. N. Wong et al. BLOOD
- Clonal hematopoiesis of indeterminate potential and its distinction from myelodysplastic syndromes
- (2015) D. P. Steensma et al. BLOOD
- Targeting LSCs through membrane antigens selectively or preferentially expressed on these cells
- (2015) Elvira Pelosi et al. BLOOD CELLS MOLECULES AND DISEASES
- Chronic myelomonocytic leukemia with nucleophosmin (NPM1) mutation
- (2015) Jie Peng et al. EUROPEAN JOURNAL OF HAEMATOLOGY
- Clonal evolution of preleukemic hematopoietic stem cells in acute myeloid leukemia
- (2015) Stephen M. Sykes et al. EXPERIMENTAL HEMATOLOGY
- Karyotype evolution and acquisition of FLT3 or RAS pathway alterations drive progression of myelodysplastic syndrome to acute myeloid leukemia
- (2015) M. Meggendorfer et al. HAEMATOLOGICA
- Aging, clonal hematopoiesis and preleukemia: not just bad luck?
- (2015) Liran I. Shlush et al. INTERNATIONAL JOURNAL OF HEMATOLOGY
- Cancer stem cells in basic science and in translational oncology: can we translate into clinical application?
- (2015) Axel Schulenburg et al. Journal of Hematology & Oncology
- Molecular profiling of myeloid progenitor cells in multi-mutated advanced systemic mastocytosis identifies KIT D816V as a distinct and late event
- (2015) M Jawhar et al. LEUKEMIA
- Effect of Mutation Order on Myeloproliferative Neoplasms
- (2015) Christina A. Ortmann et al. NEW ENGLAND JOURNAL OF MEDICINE
- Karyotype evolution and acquisition of FLT3 or RAS pathway alterations drive progression of myelodysplastic syndrome to acute myeloid leukemia
- (2015) M. Meggendorfer et al. HAEMATOLOGICA
- The shadowlands of MDS: idiopathic cytopenias of undetermined significance (ICUS) and clonal hematopoiesis of indeterminate potential (CHIP)
- (2015) L. Malcovati et al. Hematology-American Society of Hematology Education Program
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- BRAFkinase domain mutations are present in a subset of chronic myelomonocytic leukemia with wild-typeRAS
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- Cancer: Evolution Within a Lifetime
- (2014) Marco Gerlinger et al. Annual Review of Genetics
- Somatic mutations and epigenetic abnormalities in myelodysplastic syndromes
- (2014) Raphael Itzykson et al. BEST PRACTICE & RESEARCH CLINICAL HAEMATOLOGY
- Clonal evolution and clinical correlates of somatic mutations in myeloproliferative neoplasms
- (2014) P. Lundberg et al. BLOOD
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- Unique Effects of KIT D816V in BaF3 Cells: Induction of Cluster Formation, Histamine Synthesis, and Early Mast Cell Differentiation Antigens
- (2014) M. Mayerhofer et al. JOURNAL OF IMMUNOLOGY
- Boveri at 100: cancer evolution, from preneoplasia to malignancy
- (2014) Nicholas A Wright JOURNAL OF PATHOLOGY
- Pre-leukemic evolution of hematopoietic stem cells: the importance of early mutations in leukemogenesis
- (2014) M R Corces-Zimmerman et al. LEUKEMIA
- Age-related mutations associated with clonal hematopoietic expansion and malignancies
- (2014) Mingchao Xie et al. NATURE MEDICINE
- Clonal Hematopoiesis and Blood-Cancer Risk Inferred from Blood DNA Sequence
- (2014) Giulio Genovese et al. NEW ENGLAND JOURNAL OF MEDICINE
- Age-Related Clonal Hematopoiesis Associated with Adverse Outcomes
- (2014) Siddhartha Jaiswal et al. NEW ENGLAND JOURNAL OF MEDICINE
- Genomic and functional analysis of leukemic transformation of myeloproliferative neoplasms
- (2014) Raajit Rampal et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The evolving genomic landscape of myeloproliferative neoplasms
- (2014) J. Nangalia et al. Hematology-American Society of Hematology Education Program
- Comprehensive mutational profiling in advanced systemic mastocytosis
- (2013) J. Schwaab et al. BLOOD
- The genetic basis of myelodysplasia and its clinical relevance
- (2013) M. Cazzola et al. BLOOD
- Investigation of 305 patients with myelodysplastic syndromes and 20q deletion for associated cytogenetic and molecular genetic lesions and their prognostic impact
- (2013) Ulrike Bacher et al. BRITISH JOURNAL OF HAEMATOLOGY
- Heterogeneity of Neoplastic Stem Cells: Theoretical, Functional, and Clinical Implications
- (2013) P. Valent et al. CANCER RESEARCH
- Somatic D816V KIT mutation in a case of adult-onset familial mastocytosis
- (2013) Roberta Zanotti et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Long-term follow-up of treatment with imatinib in eosinophilia-associated myeloid/lymphoid neoplasms with PDGFR rearrangements in blast phase
- (2013) G Metzgeroth et al. LEUKEMIA
- A role for reactive oxygen species in JAK2 V617F myeloproliferative neoplasm progression
- (2013) C Marty et al. LEUKEMIA
- Landscape of genetic lesions in 944 patients with myelodysplastic syndromes
- (2013) T Haferlach et al. LEUKEMIA
- Somatic Mutations of Calreticulin in Myeloproliferative Neoplasms
- (2013) Thorsten Klampfl et al. NEW ENGLAND JOURNAL OF MEDICINE
- Outcome of patients with splanchnic venous thrombosis presenting without overt MPN: A role for the JAK2 V617F mutation re-evaluation
- (2013) Donatella Colaizzo et al. THROMBOSIS RESEARCH
- Concise Review: Preleukemic Stem Cells: Molecular Biology and Clinical Implications of the Precursors to Leukemia Stem Cells
- (2013) Ashley Pandolfi et al. Stem Cells Translational Medicine
- FLT3mutations in myelodysplastic syndrome and chronic myelomonocytic leukemia
- (2012) Naval Daver et al. AMERICAN JOURNAL OF HEMATOLOGY
- Clinical significance of genetic aberrations in secondary acute myeloid leukemia
- (2012) Jelena D. Milosevic et al. AMERICAN JOURNAL OF HEMATOLOGY
- Clonal evolution in cancer
- (2012) Mel Greaves et al. NATURE
- Recurrent somatic TET2 mutations in normal elderly individuals with clonal hematopoiesis
- (2012) Lambert Busque et al. NATURE GENETICS
- Clonal Architecture of Secondary Acute Myeloid Leukemia
- (2012) Matthew J. Walter et al. NEW ENGLAND JOURNAL OF MEDICINE
- Clonal Evolution of Preleukemic Hematopoietic Stem Cells Precedes Human Acute Myeloid Leukemia
- (2012) M. Jan et al. Science Translational Medicine
- CBL, CBLB, TET2, ASXL1, and IDH1/2 mutations and additional chromosomal aberrations constitute molecular events in chronic myelogenous leukemia
- (2011) H. Makishima et al. BLOOD
- Molecular Genetics of Adult Acute Myeloid Leukemia: Prognostic and Therapeutic Implications
- (2011) Guido Marcucci et al. JOURNAL OF CLINICAL ONCOLOGY
- A deep-sequencing study of chronic myeloid leukemia patients in blast crisis (BC-CML) detects mutations in 76.9% of cases
- (2011) V Grossmann et al. LEUKEMIA
- Landscape of TET2 mutations in acute myeloid leukemia
- (2011) S Weissmann et al. LEUKEMIA
- Genetic Analysis of Transforming Events That Convert Chronic Myeloproliferative Neoplasms to Leukemias
- (2010) O. Abdel-Wahab et al. CANCER RESEARCH
- RAS Mutations Contribute to Evolution of Chronic Myelomonocytic Leukemia to the Proliferative Variant
- (2010) C. Ricci et al. CLINICAL CANCER RESEARCH
- Targeting of Leukemia-Initiating Cells to Develop Curative Drug Therapies: Straightforward but Nontrivial Concept
- (2010) P. Valent CURRENT CANCER DRUG TARGETS
- High-density single nucleotide polymorphism array analysis and ASXL1 gene mutation screening in chronic myeloid leukemia during disease progression
- (2010) J Boultwood et al. LEUKEMIA
- RUNX1 mutations are frequent in chronic myelomonocytic leukemia and mutations at the C-terminal region might predict acute myeloid leukemia transformation
- (2009) M-C Kuo et al. LEUKEMIA
- Translation of the Philadelphia chromosome into therapy for CML
- (2008) B. J. Druker BLOOD
- Genome profiling of chronic myelomonocytic leukemia: frequent alterations of RAS and RUNX1genes
- (2008) Véronique Gelsi-Boyer et al. BMC CANCER
- Advances in molecular genetics and treatment of core-binding factor acute myeloid leukemia
- (2008) Krzysztof Mrózek et al. CURRENT OPINION IN ONCOLOGY
- Five years since the discovery of FIP1L1–PDGFRA: what we have learned about the fusion and other molecularly defined eosinophilias
- (2008) J Gotlib et al. LEUKEMIA
- JAK2 and MPL mutations in myeloproliferative neoplasms: discovery and science
- (2008) O Kilpivaara et al. LEUKEMIA
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