Exosomal Expression of CXCR4 Targets Cardioprotective Vesicles to Myocardial Infarction and Improves Outcome after Systemic Administration

Cardioprotection by cardiac progenitor cell-secreted exosomes: role of pregnancy-associated plasma protein-A

(2018) Lucio Barile et al.   CARDIOVASCULAR RESEARCH

A mechanistic roadmap for the clinical application of cardiac cell therapies

(2018) Eduardo Marbán   Nature Biomedical Engineering

Practical guidelines for rigor and reproducibility in preclinical and clinical studies on cardioprotection

(2018) Hans Erik Bøtker et al.   BASIC RESEARCH IN CARDIOLOGY

Engineered Exosomes With Ischemic Myocardium‐Targeting Peptide for Targeted Therapy in Myocardial Infarction

(2018) Xu Wang et al.   Journal of the American Heart Association

Exosomes From Human Cardiac Progenitor Cells for Therapeutic Applications: Development of a GMP-Grade Manufacturing Method

(2018) Gabriella Andriolo et al.   Frontiers in Physiology

Exosomes: Therapy delivery tools and biomarkers of diseases

(2017) Lucio Barile et al.   PHARMACOLOGY & THERAPEUTICS

The Role of SDF-1/CXCR4/CXCR7 in Neuronal Regeneration after Cerebral Ischemia

(2017) Xi Cheng et al.   Frontiers in Neuroscience

Induced Pluripotent Stem (IPS) Cells to Assess the Cardioprotective and Proangiogenic Activities of Exosomes Secreted by Human Cardiac Progenitor Cells

(2016) Claudia Altomare et al.   BIOPHYSICAL JOURNAL

Exosomes secreted by cardiosphere-derived cells reduce scarring, attenuate adverse remodelling, and improve function in acute and chronic porcine myocardial infarction

(2016) Romain Gallet et al.   EUROPEAN HEART JOURNAL

Cardiomyocyte-derived CXCL12 is not involved in cardiogenesis but plays a crucial role in myocardial infarction

(2016) Silke Mühlstedt et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Intravenous administration of xenogenic adipose-derived mesenchymal stem cells (ADMSC) and ADMSC-derived exosomes markedly reduced brain infarct volume and preserved neurological function in rat after acute ischemic stroke

(2016) Kuan-Hung Chen et al.   Oncotarget

Sustained myocardial production of stromal cell-derived factor-1α was associated with left ventricular adverse remodeling in patients with myocardial infarction

(2015) Manabu Uematsu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

In Vivo Imaging Reveals Extracellular Vesicle-Mediated Phenocopying of Metastatic Behavior

(2015) Anoek Zomer et al.   CELL

The CXCR4/CXCR7/CXCL12 Axis Is Involved in a Secondary but Complex Control of Neuroblastoma Metastatic Cell Homing

(2015) Annick Mühlethaler-Mottet et al.   PLoS One

Biodistribution and function of extracellular miRNA-155 in mice

(2015) Shashi Bala et al.   Scientific Reports

Exosomes Secreted from CXCR4 Overexpressing Mesenchymal Stem Cells Promote Cardioprotection via Akt Signaling Pathway following Myocardial Infarction

(2015) Kai Kang et al.   Stem Cells International

Intravenous Cardiac Stem Cell-Derived Exosomes Ameliorate Cardiac Dysfunction in Doxorubicin Induced Dilated Cardiomyopathy

(2015) Adam C. Vandergriff et al.   Stem Cells International

Exosomes for Intramyocardial Intercellular Communication

(2015) Elisabetta Cervio et al.   Stem Cells International

Extracellular vesicles from human cardiac progenitor cells inhibit cardiomyocyte apoptosis and improve cardiac function after myocardial infarction

(2014) L. Barile et al.   CARDIOVASCULAR RESEARCH

Exosomes as Critical Agents of Cardiac Regeneration Triggered by Cell Therapy

(2014) Ahmed Gamal-Eldin Ibrahim et al.   Stem Cell Reports

Visualization and in vivo tracking of the exosomes of murine melanoma B16-BL6 cells in mice after intravenous injection

(2013) Yuki Takahashi et al.   JOURNAL OF BIOTECHNOLOGY

Mesenchymal stem cell-derived exosomes increase ATP levels, decrease oxidative stress and activate PI3K/Akt pathway to enhance myocardial viability and prevent adverse remodeling after myocardial ischemia/reperfusion injury

(2013) Fatih Arslan et al.   Stem Cell Research

Cardiac Stem Cell Therapy: Stemness or Commitment?

(2012) Ashish Mehta et al.   CELL TRANSPLANTATION

Visualization of cell cycle in mouse embryos with Fucci2 reporter directed by Rosa26 promoter

(2012) T. Abe et al.   DEVELOPMENT

Ultrastructural Evidence of Exosome Secretion by Progenitor Cells in Adult Mouse Myocardium and Adult Human Cardiospheres

(2012) Lucio Barile et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Genetically modified adipose tissue−derived mesenchymal stem cells overexpressing CXCR4 display increased motility, invasiveness, and homing to bone marrow of NOD/SCID mice

(2011) Sylwia Bobis-Wozowicz et al.   EXPERIMENTAL HEMATOLOGY

Mesenchymal Stem Cells Overexpressing CXCR4 Attenuate Remodeling of Postmyocardial Infarction by Releasing Matrix Metalloproteinase-9

(2011) Wei Huang et al.   STEM CELLS AND DEVELOPMENT

Exosome secreted by MSC reduces myocardial ischemia/reperfusion injury

(2010) Ruenn Chai Lai et al.   Stem Cell Research

Gene delivery into ischemic myocardium by double-targeted lipoplexes with anti-myosin antibody and TAT peptide

(2008) Y T Ko et al.   GENE THERAPY

Over-expression of CXCR4 on mesenchymal stem cells augments myoangiogenesis in the infarcted myocardium

(2008) Dongsheng Zhang et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY