KRAS mutations in the parental tumour accelerate in vitro growth of tumoroids established from colorectal adenocarcinoma

Patient-derived organoids model treatment response of metastatic gastrointestinal cancers

(2018) Georgios Vlachogiannis et al.   SCIENCE

CORRIGENDUM: ACMG recommendations for reporting of incidental findings in clinical exome and genome sequencing

(2017) Robert C Green et al.   GENETICS IN MEDICINE

Colorectal Carcinoma: A General Overview and Future Perspectives in Colorectal Cancer

(2017) Inés Mármol et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Short-term spheroid culture of primary colorectal cancer cells as an in vitro model for personalizing cancer medicine

(2017) Maria Jeppesen et al.   PLoS One

Colorectal carcinomas with KRAS codon 12 mutation are associated with more advanced tumor stages

(2015) Wenbin Li et al.   BMC CANCER

Colorectal cancer-derived tumor spheroids retain the characteristics of original tumors

(2015) Sun-Hwa Lee et al.   CANCER LETTERS

Prospective Derivation of a Living Organoid Biobank of Colorectal Cancer Patients

(2015) Marc van de Wetering et al.   CELL

KrasG12D induces EGFR-MYC cross signaling in murine primary pancreatic ductal epithelial cells

(2015) S Diersch et al.   ONCOGENE

Transgenic mouse model expressing P53R172H, luciferase, EGFP and KRASG12D in a single open reading frame for live imaging of tumor

(2015) Hye-Lim Ju et al.   Scientific Reports

Mechanisms of resistance to EGFR tyrosine kinase inhibitors

(2015) Lihua Huang et al.   Acta Pharmaceutica Sinica B

Clinical Validation of Targeted Next Generation Sequencing for Colon and Lung Cancers

(2015) Nicky D’Haene et al.   PLoS One

BRAF V600E mutation and KRAS codon 13 mutations predict poor survival in Chinese colorectal cancer patients

(2014) Jing Chen et al.   BMC CANCER

Real-Time Optical Antimicrobial Susceptibility Testing

(2013) M. Fredborg et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Comprehensive molecular characterization of human colon and rectal cancer

(2012)   NATURE

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Retaining cell-cell contact enables preparation and culture of spheroids composed of pure primary cancer cells from colorectal cancer

(2011) J. Kondo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multicellular tumor spheroids: An underestimated tool is catching up again

(2010) Franziska Hirschhaeuser et al.   JOURNAL OF BIOTECHNOLOGY

Newly characterised ex vivo colospheres as a three-dimensional colon cancer cell model of tumour aggressiveness

(2009) L-B Weiswald et al.   BRITISH JOURNAL OF CANCER

Differential effects of oncogenic K-Ras and N-Ras on proliferation, differentiation and tumor progression in the colon

(2008) Kevin M Haigis et al.   NATURE GENETICS