Modulating antibody-dependent cellular cytotoxicity of epidermal growth factor receptor-specific heavy-chain antibodies through hinge engineering

Size-Dependent Segregation Controls Macrophage Phagocytosis of Antibody-Opsonized Targets

(2018) Matthew H. Bakalar et al.   CELL

Antigen recognition by single-domain antibodies: structural latitudes and constraints

(2018) Kevin A. Henry et al.   mAbs

Structure and hydrodynamics of a DNA G-quadruplex with a cytosine bulge

(2018) Markus Meier et al.   NUCLEIC ACIDS RESEARCH

Camelid single-domain antibodies raised by DNA immunization are potent inhibitors of EGFR signaling

(2018) Martin A. Rossotti et al.   BIOCHEMICAL JOURNAL

Immunological Functions and Evolutionary Emergence of Heavy-Chain Antibodies

(2018) Cory L. Brooks et al.   TRENDS IN IMMUNOLOGY

Antibody Distance from the Cell Membrane Regulates Antibody Effector Mechanisms

(2017) Kirstie L. S. Cleary et al.   JOURNAL OF IMMUNOLOGY

Human IgG1, IgG3, and IgG3 Hinge-Truncated Mutants Show Different Protection Capabilities against Meningococci Depending on the Target Antigen and Epitope Specificity

(2016) S. Giuntini et al.   Clinical and Vaccine Immunology

Biophysical analysis of a lethal laminin alpha-1 mutation reveals altered self-interaction

(2016) Trushar R. Patel et al.   MATRIX BIOLOGY

The Highly Evolvable Antibody Fc Domain

(2016) Hye In Park et al.   TRENDS IN BIOTECHNOLOGY

Development of a robust reporter-based ADCC assay with frozen, thaw-and-use cells to measure Fc effector function of therapeutic antibodies

(2014) Zhijie Jey Cheng et al.   JOURNAL OF IMMUNOLOGICAL METHODS

The availability of glucose to CHO cells affects the intracellular lipid-linked oligosaccharide distribution, site occupancy and the N-glycosylation profile of a monoclonal antibody

(2013) Bo Liu et al.   JOURNAL OF BIOTECHNOLOGY

Engineering Upper Hinge Improves Stability and Effector Function of a Human IgG1

(2011) Boxu Yan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Engineered Single-Domain Antibodies with High Protease Resistance and Thermal Stability

(2011) Greg Hussack et al.   PLoS One

Unique carbohydrate-carbohydrate interactions are required for high affinity binding between Fc RIII and antibodies lacking core fucose

(2011) C. Ferrara et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Superior In vivo Efficacy of Afucosylated Trastuzumab in the Treatment of HER2-Amplified Breast Cancer

(2010) Teemu T. Junttila et al.   CANCER RESEARCH

Differential tumor-targeting abilities of three single-domain antibody formats

(2009) Andrea Bell et al.   CANCER LETTERS

Immunoglobulin G Fragment C Receptor Polymorphisms and Clinical Efficacy of Trastuzumab-Based Therapy in Patients With HER-2/neu–Positive Metastatic Breast Cancer

(2008) Antonino Musolino et al.   JOURNAL OF CLINICAL ONCOLOGY

Transient expression and purification of chimeric heavy chain antibodies

(2008) Jianbing Zhang et al.   PROTEIN EXPRESSION AND PURIFICATION