Article
Medicine, Research & Experimental
Samyuktha Melachuri, Benita Valappil, Carl Snyderman
Summary: This study aimed to compare the management and outcomes of carotid body tumor surgeries within different surgical specialties in the same healthcare system. Results showed that patients with advanced tumors were more likely to undergo preoperative embolization and sustain carotid artery injury. Collaborative surgeries had worse outcomes due to more advanced tumors requiring more complex surgeries.
Article
Medicine, General & Internal
Dat Tin Nguyen, Akos Berczi, Balazs Bence Nyarady, Adam Szonyi, Marton Philippovich, Edit Dosa
Summary: The aim of this retrospective study was to evaluate the effectiveness of stenting in patients with isolated distal internal carotid artery stenosis or post-surgical restenosis. The study found that the early neurological complication rate was acceptable for distal internal carotid artery (re)stenosis patients, but the mid-term mortality rate was high for post-surgical restenosis patients.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Clinical Neurology
Alhamza R. Al-Bayati, Raul G. Nogueira, Diogo C. Haussen
Summary: Ischemic stroke is a leading cause of mortality and long-term disability worldwide. The increasing availability of advanced cerebrovascular imaging modalities continues to unravel atherosclerotic and nonatherosclerotic carotid steno-occlusive disease as a common culprit of cerebral ischemia. Individualized treatment strategies targeting each etiologic subset would optimize preventive measures and minimize recurrence of cerebral ischemia.
Article
Clinical Neurology
Svatopluk Ostry, Milan Nevsimal, Martin Reiser, Richard Voldrich, Ondrej Krticka, Jiri Kubale, Miroslava Nevsimalova, Jiri Fiedler
Summary: The study demonstrates the value of intraoperative somatosensory evoked potential (SEP) and selective shunting in preventing intraoperative ischemia during urgent extracranial internal carotid artery (eICA) recanalization. The decrease in intraoperative SEP amplitude can serve as an effective measure to guide the surgical procedure and improve clinical outcomes.
CLINICAL NEUROPHYSIOLOGY
(2022)
Article
Clinical Neurology
Haibin Gao, Wei You, Dachao Wei, Jian Lv, Wei Sun, Youxiang Li
Summary: This study investigated the association between parent artery tortuosity and treatment outcomes in patients with internal carotid artery aneurysms. The study found that parent artery tortuosity was associated with in-stent stenosis, but not with aneurysm complete occlusion.
FRONTIERS IN NEUROLOGY
(2022)
Review
Cardiac & Cardiovascular Systems
Christopher J. White, Thomas G. Brott, William A. Gray, Donald Heck, Tudor Jovin, Sean P. Lyden, David Christopher Metzger, Kenneth Rosenfield, Gary Roubin, Ravish Sachar, Adnan Siddiqui
Summary: Significant advances have been made in the field of carotid artery stenting, with new trial data, professional statements, new techniques, and better candidate selection methods. The outdated coverage decision regarding CAS should be updated to approve CAS in selected symptomatic and asymptomatic patients for stroke prevention. Optimized CAS strategies and new technologies are leading to improved outcomes in CAS procedures.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2021)
Article
Medicine, General & Internal
Alison Halliday, Richard Bulbulia, Leo H. Bonati, Johanna Chester, Andrea Cradduck-Bamford, Richard Peto, Hongchao Pan
Summary: The international multicentre randomised trial ACST-2 compared the effects of CAS and CEA for asymptomatic patients with severe stenosis, showing that the long-term effects of these two procedures on fatal or disabling stroke are comparable.
Review
Cardiac & Cardiovascular Systems
Christopher J. White, Thomas G. Brott, William A. Gray, Donald Heck, Tudor Jovin, Sean P. Lyden, David Christopher Metzger, Kenneth Rosenfield, Gary Roubin, Ravish Sachar, Adnan Siddiqui
Summary: Significant advances have been made in carotid artery stenting (CAS), including new trial data, professional societal statements, techniques, and devices. The improved selection of CAS candidates and assessment of procedure risk have led to better outcomes.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2022)
Article
Clinical Neurology
Francis J. Jareczek, Mary Beth Farrell, Erik B. Lehman, Cathy Sila, John B. Terry, David Sacks, Paul Kalapos, Scott D. Simon, Kevin M. Cockroft
Summary: This study compared the measurements of carotid artery stenosis by real-world physicians to those measured by independent expert reviewers. The results showed that real-world operators tend to overestimate the degree of carotid artery stenosis.
Article
Multidisciplinary Sciences
Yaxuan Sun, Yongxia Ding, Kun Meng, Bin Han, Jing Wang, Yan Han
Summary: This study found that carotid artery endarterectomy (CEA) and carotid artery stenting (CAS) resulted in similar outcomes for patients with contralateral carotid occlusion (CCO), with the risk of death being lower for patients treated with CEA. Further high-level evidence is needed to confirm these results.
Article
Radiology, Nuclear Medicine & Medical Imaging
Aldo Paolucci, Anna Maria Ierardi, Sophia Hohenstatt, Viviana Grassi, Silvia Romagnoli, Lorenzo Pignataro, Santi Trimarchi, Gianpaolo Carrafiello
Summary: In this study, the authors reported the first experience of direct percutaneous puncture technique using the low-viscosity formula of SQUID-12 for pre-operative embolization of carotid body paragangliomas. The additional use of a transitory balloon-blockage at the origin of the external carotid artery aims to provide higher protection and reduce the risk of non-target embolization and subsequent neurological sequelae. The results showed that this technique is safe and efficient with few complications.
Article
Clinical Neurology
Roger M. Krzyzewski, Kornelia M. Klis, Borys M. Kwinta, Bartlomiej Lasocha, Pawel Brzegowy, Tadeusz J. Popiela, Jerzy Gasowski
Summary: There is a correlation between tortuosity of arteries and the development and rupture of aneurysms. Lower tortuosity of the internal carotid artery may protect against rupture of aneurysms, while higher tortuosity is associated with aneurysm growth.
WORLD NEUROSURGERY
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Xiangyue Zha, Qin Liu, Kan Deng, Xiaodan Lu, Yikai Xu
Summary: This study used computed tomography perfusion (CTP) to explore the risk of intracranial hemorrhage (ICH) after internal carotid artery stenting (CAS) in patients with symptomatic severe carotid stenosis. The results showed that CTP parameters, especially rMTT, can be used to predict the occurrence of ICH. Patients with a preoperative rMTT >1.88 should be closely monitored for evidence of ICH after CAS.
QUANTITATIVE IMAGING IN MEDICINE AND SURGERY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Xiangyue Zha, Qin Liu, Kan Deng, Xiaodan Lu, Yikai Xu
Summary: This study investigated the risk of intracranial hemorrhage (ICH) after carotid artery stenting (CAS) in patients with severe carotid stenosis using computed tomography perfusion (CTP). The results showed that the relative mean transit time (rMTT) derived from CTP was the most effective parameter for predicting ICH.
QUANTITATIVE IMAGING IN MEDICINE AND SURGERY
(2023)
Article
Oncology
Ziming Ye, Chao Huang, Lizhou Wang, Shi Zhou, Xing Li, Min Xu
Summary: This retrospective study investigated the clinical efficacy and safety of carotid artery stenting (CAS) in elderly patients with internal carotid artery stenosis (ICS). The results showed that CAS treatment significantly improved the stroke severity, daily living ability, oxidative stress, inflammatory cytokines, and cognitive function of elderly ICS patients. The complication rate in the CAS group was comparable to that in the control group.
AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH
(2022)
Review
Environmental Sciences
Saeed M. Alghamdi, Ahmed M. Al Rajah, Yousef S. Aldabayan, Abdulelah M. Aldhahir, Jaber S. Alqahtani, Abdulaziz A. Alzahrani
Summary: Current telehealth interventions for COPD have an average acceptance rate of 51%, but come with a high dropout rate of 63%. Acceptance and dropout levels in telehealth clinical trials can be influenced by sociodemographic and intervention-related factors.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2021)
Editorial Material
Primary Health Care
Jaber S. Alqahtani, Abdulelah M. Aldhahir, Tope Oyelade, Saeed M. Alghamdi, Ahmad S. Almamary
Summary: Evidence shows that smokers are more vulnerable to severe COVID-19 and more likely to be infected due to the nature of smoking behavior, therefore promoting smoking cessation is crucial during the pandemic.
NPJ PRIMARY CARE RESPIRATORY MEDICINE
(2021)
Article
Otorhinolaryngology
Hemail M. Alsubaie, Suhail Sayed, Albaraa Y. Alsini, Haddad H. Alkaff, Osama A. Margalani, Ahmed Abu-Zaid, Omar A. Abu-Suliman, Ameen Z. Alherabi, Saeed A. Alghamdi, Essam Saleh, Mohammad A. Alessa, Sherif K. Abdelmonim
Summary: This study validated the Arabic version of MDADI among H&N cancer patients from Saudi Arabia, demonstrating high internal consistency and concurrent validity.
Article
Chemistry, Multidisciplinary
Abrar Alhazmi, Olaiyan Alolaiyan, Majed Alharbi, Saeed Alghamdi, Awsaf Alsulami, Faisal Alamri, Shahad Albawardi, Ghadeer Aljalham, Sarah Alsaggaf, Khalid Alhamdan, Moh R. Amer
Summary: In this study, a van der Waals field-effect transistor (VdW-FET) based on GeS was investigated, showing resonant tunneling behavior at room temperature due to VdW doping via black phosphorus (BP) and multiple decades of negative differential resistance (NDR) during doping transient state. A noticeable conductivity switch from low p-type to high n-type was observed with a conductivity enhancement of 2 orders of magnitude in doped GeS devices. These results indicate the potential of electrical oscillators and switching devices for next generation nanoelectronics.
ADVANCED FUNCTIONAL MATERIALS
(2022)
Article
Nutrition & Dietetics
Nahla Ayoub, Nadia Badr, Saeed S. Al-Ghamdi, Safaa Alsanosi, Abdullah R. Alzahrani, Ashraf B. Abdel-Naim, Khaled A. Nematallah, Noha Swilam
Summary: Salvadora persica ethyl acetate fraction (SPEAF) exhibits excellent activities in the treatment of acetic acid-induced oral ulcers in rats, including promoting healing, anti-inflammatory, antioxidant, and angiogenic effects.
Article
Nutrition & Dietetics
Hamza Zafar, Noor ul Ain, Abdulrahman Alshammari, Saeed Alghamdi, Hafsa Raja, Amjad Ali, Abubakar Siddique, Syeda Duaa Tahir, Samina Akbar, Maryum Arif, Metab Alharbi, Abdur Rahman
Summary: This study isolated probiotic Lactobacillus strains from traditional yoghurt and yogurt milk and evaluated their cholesterol-lowering and anti-obesity effects in a high cholesterol high fat diet model in Wistar rats. The strains showed significant improvement in blood lipid profiles, comparable to statins, and helped control weight gain in animals on the high fat high cholesterol diet, indicating their potential for preventing heart diseases and managing weight.
Article
Medicine, Research & Experimental
Ibrahim M. Al-Anazi, Mohammed S. Al-Qhtany, Ahmad S. Al-Zahrani, Osama H. Al-Zahrani, Abdullah R. Al-Harbi, Abdullah R. Alzahrani, Mahdi Alsugoor, Saeed S. Al-Ghamdi
Summary: This study aimed to assess the awareness of forensic medicine among medical students at Umm Al-Qura University and identify factors influencing their choice to pursue a career in forensic medicine. The results showed that most students had poor awareness of forensic medicine and believed that there was insufficient information about it in their curriculum. However, many students expressed the need for more education on forensic science and were open to specializing in the field.
Article
Medicine, General & Internal
Fahad M. Althobaiti, Safaa M. Alsanosi, Alaa H. Falemban, Abdullah R. Alzahrani, Salma A. Fataha, Sara O. Salih, Ali M. Alrumaih, Khalid N. Alotaibi, Hazim M. Althobaiti, Saeed S. Al-Ghamdi, Nahla Ayoub
Summary: The study assessed the efficacy and safety of empagliflozin (EMPA) in Saudi patients with T2DM. The results showed that EMPA, as an add-on therapy, significantly improved glycemic control, reduced body weight, improved kidney function, and had a positive impact on lipid levels.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Chemistry, Medicinal
Bidisha Rajkhowa, Sidharth Mehan, Pranshul Sethi, Aradhana Prajapati, Manisha Suri, Sumit Kumar, Sonalika Bhalla, Acharan S. Narula, Abdulrahman Alshammari, Metab Alharbi, Nora Alkahtani, Saeed Alghamdi, Reni Kalfin
Summary: This study investigated the neuroprotective potential of Solanesol (SNL) in rats with bipolar disorder (BD) and found that SNL may improve BD-like neurological dysfunctions by activating the SIRT-1 signaling pathway.
Article
Medicine, Research & Experimental
Rahmah Alsilmi, Saeed Alghamdi, Salim Alghamdi, Raad Alshahrani, Ahmed Alyoubi, Omar Almassari, Mohammed Alshaikhi, Ahmed Barefah, Amr Ajlan, Ayman Eskander, Fatima Jabali, Mohammad Mustafa
Summary: This study retrospectively reviewed the chest CTs of 44 patients with SCD and ACS. The findings showed that inflammatory changes in the lung parenchyma, mainly in the lower lung zones, were common during ACS episodes. The most frequent abnormalities were consolidation and cardiomegaly. Pulmonary fibrosis was noted in one-third of the patients.
Article
Infectious Diseases
Amal Oweid Almutairi, Mahmoud Zaki El-Readi, Mohammad Althubiti, Yosra Zakariyya Alhindi, Nahla Ayoub, Abdullah R. Alzahrani, Saeed S. Al-Ghamdi, Safaa Yehia Eid
Summary: This study investigated the prevalence of liver injury in COVID-19 patients treated with Favipiravir in a hospital in Saudi Arabia. The results showed that Favipiravir had adverse effects on the liver, leading to increased levels of liver function parameters.
TROPICAL MEDICINE AND INFECTIOUS DISEASE
(2023)
Article
Surgery
Melissa Laus, Elena Festa Kotelnikova, Fiorella Cazzato, Antonio Buonamico, Adelchi Croce
Summary: This study evaluated the clinical value and role of F-18-FDG PET/CT in the follow-up of HNSCC patients. The results showed that PET/CT is reliable for evaluating tumor response and making important clinical decisions.
Article
Medicine, General & Internal
Mohammad H. Shaheen, Sara Bayounos, Elsaeid M. Thabet, Bassam Al-zuraiqi, Khalid Badr, Saeed A. Alghamdi, Fares E. AlGhamdi
Summary: This case report describes the improvement of hearing and middle ear aeration and Eustachian tube function through body weight reduction.
CUREUS JOURNAL OF MEDICAL SCIENCE
(2022)
Article
Energy & Fuels
Saeed A. Al-Ghamdi
Summary: This paper collected and analyzed solar irradiance data in Al-Aqiq province, KSA, and developed linear and nonlinear correlations using regression techniques to estimate global solar radiation. The results indicate that the region has great solar energy potential and the presented correlations accurately predict daily global radiation.
INTERNATIONAL JOURNAL OF ENERGY AND ENVIRONMENTAL ENGINEERING
(2022)
Meeting Abstract
Clinical Neurology
Osama Khojah, Saeed Alghamdi
