Nuclear pore density controls heterochromatin reorganization during senescence

Nuclear Pores Promote Lethal Prostate Cancer by Increasing POM121-Driven E2F1, MYC, and AR Nuclear Import

(2018) Veronica Rodriguez-Bravo et al.   CELL

Tpr regulates the total number of nuclear pore complexes per cell nucleus

(2018) Asako McCloskey et al.   GENES & DEVELOPMENT

Integrative structure and functional anatomy of a nuclear pore complex

(2018) Seung Joong Kim et al.   NATURE

Massive reshaping of genome–nuclear lamina interactions during oncogene-induced senescence

(2017) Christelle Lenain et al.   GENOME RESEARCH

Nuclear pore complex plasticity during developmental process as revealed by super-resolution microscopy

(2017) Julien Sellés et al.   Scientific Reports

Loss of lamin B receptor is necessary to induce cellular senescence

(2016) Emilie Lukášová et al.   BIOCHEMICAL JOURNAL

Chromatin organization at the nuclear pore favours HIV replication

(2015) Mickaël Lelek et al.   Nature Communications

LBR and Lamin A/C Sequentially Tether Peripheral Heterochromatin and Inversely Regulate Differentiation

(2013) Irina Solovei et al.   CELL

Redistribution of the Lamin B1 genomic binding profile affects rearrangement of heterochromatic domains and SAHF formation during senescence

(2013) M. Sadaie et al.   GENES & DEVELOPMENT

A complex secretory program orchestrated by the inflammasome controls paracrine senescence

(2013) Juan Carlos Acosta et al.   NATURE CELL BIOLOGY

A Change in Nuclear Pore Complex Composition Regulates Cell Differentiation

(2012) Maximiliano A. D'Angelo et al.   DEVELOPMENTAL CELL

Independence of Repressive Histone Marks and Chromatin Compaction during Senescent Heterochromatic Layer Formation

(2012) Tamir Chandra et al.   MOLECULAR CELL

Nuclear pore complex composition: a new regulator of tissue-specific and developmental functions

(2012) Marcela Raices et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Senescence-associated heterochromatin foci are dispensable for cellular senescence, occur in a cell type- and insult-dependent manner and follow expression of p16ink4a

(2011) Martin Kosar et al.   CELL CYCLE

Control of the senescence-associated secretory phenotype by NF- B promotes senescence and enhances chemosensitivity

(2011) Y. Chien et al.   GENES & DEVELOPMENT

Localization of Pom121 to the inner nuclear membrane is required for an early step of interphase nuclear pore complex assembly

(2011) Tomoko Funakoshi et al.   MOLECULAR BIOLOGY OF THE CELL

Interplay between oncogene-induced DNA damage response and heterochromatin in senescence and cancer

(2011) Raffaella Di Micco et al.   NATURE CELL BIOLOGY

The Senescence-Associated Secretory Phenotype: The Dark Side of Tumor Suppression

(2010) Jean-Philippe Coppé et al.   Annual Review of Pathology-Mechanisms of Disease

Protein Tpr is required for establishing nuclear pore-associated zones of heterochromatin exclusion

(2010) Sandra Krull et al.   EMBO JOURNAL

Live imaging of single nuclear pores reveals unique assembly kinetics and mechanism in interphase

(2010) Elisa Dultz et al.   JOURNAL OF CELL BIOLOGY

Age-Dependent Deterioration of Nuclear Pore Complexes Causes a Loss of Nuclear Integrity in Postmitotic Cells

(2009) Maximiliano A. D'Angelo et al.   CELL

The role of nuclear pores in gene regulation, development and disease

(2009) Maya Capelson et al.   EMBO REPORTS

Chemokine Signaling via the CXCR2 Receptor Reinforces Senescence

(2008) Juan C. Acosta et al.   CELL

Domain organization of human chromosomes revealed by mapping of nuclear lamina interactions

(2008) Lars Guelen et al.   NATURE

Subdiffraction Multicolor Imaging of the Nuclear Periphery with 3D Structured Illumination Microscopy

(2008) L. Schermelleh et al.   SCIENCE