Mitochondrial metabolism is inhibited by the HIF1α-MYC-PGC-1β axis in BRAF V600E thyroid cancer

PGC-1: The Energetic Regulator in Cardiac Metabolism

(2018) Wencheng Di et al.   CURRENT ISSUES IN MOLECULAR BIOLOGY

LncRNA IDH1-AS1 links the functions of c-Myc and HIF1α via IDH1 to regulate the Warburg effect

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Elucidating the Metabolic Plasticity of Cancer: Mitochondrial Reprogramming and Hybrid Metabolic States

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Trends in Thyroid Cancer Incidence and Mortality in the United States, 1974-2013

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PKM2 methylation by CARM1 activates aerobic glycolysis to promote tumorigenesis

(2017) Fabao Liu et al.   NATURE CELL BIOLOGY

Reactive oxygen species-driven HIF1α triggers accelerated glycolysis in endothelial cells exposed to low oxygen tension

(2017) Jin-Young Paik et al.   NUCLEAR MEDICINE AND BIOLOGY

A genome-wide association study yields five novel thyroid cancer risk loci

(2017) Julius Gudmundsson et al.   Nature Communications

Mitochondria and Cancer

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Drp1-Dependent Mitochondrial Autophagy Plays a Protective Role Against Pressure Overload–Induced Mitochondrial Dysfunction and Heart FailureCLINICAL PERSPECTIVE

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Sustained ERK inhibition maximizes responses of BrafV600E thyroid cancers to radioiodine

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Metabolic rewiring in melanoma

(2016) B I Ratnikov et al.   ONCOGENE

The Warburg Effect: How Does it Benefit Cancer Cells?

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Metabolic reprogramming supports the invasive phenotype in malignant melanoma

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(2015) Go J. Yoshida   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Therapy-induced tumour secretomes promote resistance and tumour progression

(2015) Anna C. Obenauf et al.   NATURE

Metabolic pathways promoting cancer cell survival and growth

(2015) Lindsey K. Boroughs et al.   NATURE CELL BIOLOGY

Targeting mitochondria metabolism for cancer therapy

(2015) Samuel E Weinberg et al.   Nature Chemical Biology

The role of BRAF(V600E) mutation as poor prognostic factor for the outcome of patients with intrathyroid papillary thyroid carcinoma

(2014) M.R. Pelizzo et al.   BIOMEDICINE & PHARMACOTHERAPY

Molecular Pathways: BRAF Induces Bioenergetic Adaptation by Attenuating Oxidative Phosphorylation

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Oncogene ablation-resistant pancreatic cancer cells depend on mitochondrial function

(2014) Andrea Viale et al.   NATURE

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Oncogenic BRAF Regulates Oxidative Metabolism via PGC1α and MITF

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The Increase in Thyroid Cancer Incidence During the Last Four Decades Is Accompanied by a High Frequency ofBRAFMutations and a Sharp Increase inRASMutations

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The diverse role of the PPARγ coactivator 1 family of transcriptional coactivators in cancer

(2012) Geoffrey D. Girnun   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

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Dual Inhibition of Tumor Energy Pathway by 2-Deoxyglucose and Metformin Is Effective against a Broad Spectrum of Preclinical Cancer Models

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(2010) Richard C. Scarpulla   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

BRAF V600E mutation influences hypoxia-inducible factor-1α expression levels in papillary thyroid cancer

(2010) Monica Zerilli et al.   MODERN PATHOLOGY

The BRAFV600E Oncogene Induces Transforming Growth Factor   Secretion Leading to Sodium Iodide Symporter Repression and Increased Malignancy in Thyroid Cancer

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Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

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