Article
Cardiac & Cardiovascular Systems
Janani Reisenauer, Michael J. Simoff, Michael A. Pritchett, David E. Ost, Adnan Majid, Colleen Keyes, Roberto F. Casal, Mihir S. Parikh, Javier Diaz-Mendoza, Sebastian Fernandez-Bussy, Erik E. Folch
Summary: The report describes the Ion Endoluminal System and its application in patients with small peripheral pulmonary nodules, providing reliable airway visualization and navigation for biopsy.
ANNALS OF THORACIC SURGERY
(2022)
Article
Respiratory System
David E. E. Ost
Summary: Likelihood ratios are a method to evaluate diagnostic test performance. This paper reviews the concept of likelihood ratios and provides practical examples of their application in calculating posttest disease probabilities.
JOURNAL OF BRONCHOLOGY & INTERVENTIONAL PULMONOLOGY
(2022)
Letter
Respiratory System
David E. E. Ost
JOURNAL OF BRONCHOLOGY & INTERVENTIONAL PULMONOLOGY
(2022)
Article
Respiratory System
Horiana B. Grosu, Ryan Kern, Fabien Maldonado, Roberto Casal, Clark R. Andersen, Liang Li, Georgie Eapen, David Ost, Carlos Jimenez, Frangiskos Frangopoulos, Bruce Sabath, Erik Vakil, Audra Schwalk, Mathieu Marcoux, Ala Eddin Sagar, Faria Nasim, Julie Lin, Moiz Salahudin, Hasan Muhammad Arain, Laila Noor, Diana Montanez, John Stewart, John Mullon, Michalis Michael, Ilias Porfyridis
Summary: The study found that a predictive model based on visual assessment, ROSE of touch preparation, and CT scan findings had excellent predictive accuracy for MPE. Further validation studies are needed to confirm these findings.
Article
Medicine, General & Internal
E. Lambert, S. Hollebosch, C. van Praet, S. Van Bruwaene, L. Duck, W. De Roock, S. van Wambeke, C. Ghysel, F. Ameye, P. Schatteman, F. Vandenbroucke, B. Sautois, F. Baekelandt, D. Ost, K. Fransis, B. Filleul, C. Remondo, W. Wynendaele, B. Bamelis, P. Logghe, E. Vergauwe, E. Denies, S. Joniau, N. Lumen
Summary: Real-world data showed significantly longer radiographic progression-free survival (RPFS) for mHSPC patients treated with ADT + AAP compared to ADT only or ADT + docetaxel at short-term follow-up, with no significant differences between the three groups in 1-year PSA-PFS, CSS and OS.
ACTA CLINICA BELGICA
(2022)
Article
Respiratory System
Daniel P. Steinfort, Shankar Siva, Kanishka Rangamuwa, Percy Lee, David Fielding, Phan Nguyen, Barton R. Jennings, Shaun Yo, Nick Hardcastle, Gargi Kothari, Laurence Crombag, Jouke Annema, Kazuhiro Yasufuku, David E. Ost, Louis B. Irving
Summary: Systematic evaluation of mediastinal lymph nodes by EBUS-TBNA improves accuracy of staging in NSCLC patients, and systematic mediastinal staging is helpful in determining radiation treatment fields.
BMC PULMONARY MEDICINE
(2022)
Article
Respiratory System
Anne Gonzalez, David E. Ost, Samira Shojaee
Summary: This article discusses the development and limitations of the field of diagnostic bronchoscopy, with a focus on explaining the standard measures of diagnostic accuracy and how they differ from diagnostic yield.
JOURNAL OF BRONCHOLOGY & INTERVENTIONAL PULMONOLOGY
(2022)
Article
Critical Care Medicine
Moiz Salahuddin, Mona Sarkiss, Ala-Eddin S. Sagar, Ioannis Vlahos, Christopher H. Chang, Archan Shah, Bruce F. Sabath, Julie Lin, Juhee Song, Teresa Moon, Peter H. Norman, George A. Eapen, Horiana B. Grosu, David E. Ost, Carlos A. Jimenez, Gouthami Chintalapani, Roberto F. Casal
Summary: This study compared the effects of standard ventilation and a ventilatory strategy on the incidence of atelectasis during bronchoscopy under general anesthesia. The results showed that the ventilatory strategy significantly reduced the occurrence of atelectasis and had a sustained effect over time.
Article
Respiratory System
Eduardo Tellez Garcia, David Ost, Horiana B. B. Grosu
Summary: This study aimed to evaluate if anticoagulation can interfere with successful spontaneous pleurodesis in patients treated with indwelling pleural catheters (IPC) for malignant pleural effusion (MPE). The results showed no association between anticoagulation and pleurodesis, while chemotherapy or radiotherapy after IPC placement and better performance status were associated with increased rates of pleurodesis and catheter removal.
Review
Respiratory System
Gabriela Martinez-Zayas, Sofia Molina, David E. Ost
Summary: A systematic review and meta-analysis were conducted to determine the sensitivity of thoracentesis and thoracoscopy for diagnosing malignant pleural effusions (MPE) secondary to different types of cancers. The results showed that the sensitivity of thoracentesis varied significantly across cancer types, while thoracoscopy had relatively high sensitivity. The complication rates were low for both procedures.
EUROPEAN RESPIRATORY REVIEW
(2022)
Article
Critical Care Medicine
Katrina Steiling, Hasmeena Kathuria, Chidiebere Peter Echieh, David E. Ost, M. Patricia Rivera, Abbie Begnaud, Juan C. Celedon, Marjory Chariot, Frank Dietrick, Narjust Duma, Kwun M. Fong, Jean G. Ford, Michael K. Gould, Fernando Holguin, Eliseo J. Perez-Stable, Nichole T. Tanner, Carey Conley Thomson, Renda Soylemez Wiener, Juan Wisnivesky
Summary: This article summarizes the existing evidence on interventions to reduce disparities in lung nodule evaluation, identifies knowledge gaps, and prioritizes research questions. Key knowledge gaps include a lack of standardized approaches to identify factors associated with disparities in lung nodule evaluation, limited data on the influence of social determinants of health, uncertainty regarding optimal strategies to improve patient-clinician communication, and a lack of information on the impact of patient navigators and culturally trained multidisciplinary teams.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
(2023)
Review
Respiratory System
Sami I. Bashour, David E. Ost
Summary: Bronchopleural fistulae (BPF) are rare but serious complications in cancer-related surgery. This review discusses newer diagnostic and therapeutic approaches, including bronchoscopic techniques and alternative interventions, to improve identification and outcomes of BPF management.
CURRENT OPINION IN PULMONARY MEDICINE
(2023)
Article
Respiratory System
David E. Ost, David J. Feller-Kopman, Anne V. Gonzalez, Horiana B. Grosu, Felix Herth, Peter Mazzone, John E. S. Park, Jose M. Porcel, Samira Shojaee, Ioana Tsiligianni, Anil Vachani, Jonathan Bernstein, Richard Branson, Patrick A. Flume, Cezmi A. Akdis, Martin Kolb, Esther Barreiro Portela, Alan Smyth
Summary: Diagnostic testing is crucial in medicine, but there is significant variation in the methodology, definitions, and reporting of results in studies of diagnostic testing in respiratory medicine, leading to conflicting or ambiguous results. To address this issue, a group of 20 respiratory journal editors developed reporting standards for such studies, providing a rigorous methodology for authors, peer reviewers, and researchers. The standards cover four key areas, including defining the reference standard of truth, measures of test performance for dichotomous outcomes, measures of test performance for multichotomous outcomes, and a useful definition of diagnostic yield. The importance of using contingency tables for reporting results is emphasized, along with a practical checklist for reporting diagnostic testing studies.
JOURNAL OF BRONCHOLOGY & INTERVENTIONAL PULMONOLOGY
(2023)
Article
Respiratory System
Momen M. Wahidi, Carla R. Lamb, Kevin Kovitz, Colleen Keyes, Rabih Bechara, Coral X. Giovacchini, Kim French, Samira Shojaee, Ali Musani, George Eapen, David E. Ost
Summary: Interventional pulmonology (IP) is a growing field without recognition from the American Board of Medical Specialties or national benchmark organizations, resulting in a lack of data on practice patterns, compensation, and productivity targets.
JOURNAL OF BRONCHOLOGY & INTERVENTIONAL PULMONOLOGY
(2023)
Article
Health Care Sciences & Services
Ajay Sheshadri, Sukh Makhnoon, Amin M. Alousi, Lara Bashoura, Rene Andrade, Christopher J. Miller, Karen R. Stolar, Muhammad Hasan Arain, Laila Noor, Amulya Balagani, Akash Jain, David Blanco, Abel Ortiz, Michael S. Taylor, Alex Stenzler, Rohtesh Mehta, Uday R. Popat, Chitra Hosing, David E. Ost, Richard E. Champlin, Burton F. Dickey, Susan K. Peterson
Summary: This study aimed to investigate the usability and acceptability of home-based spirometry (HS) among recipients of allogeneic hematopoietic cell transplant (AHCT). The results showed that participants found HS to be highly acceptable and helpful in managing AHCT-related symptoms, as well as detecting health-related problems early. The study concluded that HS is easy to use with no significant barriers from the patient's perspective.
JMIR FORMATIVE RESEARCH
(2022)