Detecting neuroinflammation in the brain following chronic alcohol exposure in rats: A comparison between in vivo and in vitro TSPO radioligand binding

5-ALA in the management of malignant glioma

(2018) Herbert Stepp et al.   LASERS IN SURGERY AND MEDICINE

Influence of alcoholism and cholesterol on TSPO binding in brain: PET [11C]PBR28 studies in humans and rodents

(2018) Sung Won Kim et al.   NEUROPSYCHOPHARMACOLOGY

TSPO in diverse CNS pathologies and psychiatric disease: A critical review and a way forward

(2018) Tomás R. Guilarte   PHARMACOLOGY & THERAPEUTICS

The Low-Affinity Binding of Second Generation Radiotracers Targeting TSPO is Associated with a Unique Allosteric Binding Site

(2017) Camilo Rojas et al.   Journal of Neuroimmune Pharmacology

Microglial-derived miRNA let-7 and HMGB1 contribute to ethanol-induced neurotoxicity via TLR7

(2017) Leon G. Coleman et al.   Journal of Neuroinflammation

Increased Expression of Translocator Protein (TSPO) Marks Pro-inflammatory Microglia but Does Not Predict Neurodegeneration

(2017) Lien Beckers et al.   MOLECULAR IMAGING AND BIOLOGY

In vivo imaging of translocator protein, a marker of activated microglia, in alcohol dependence

(2017) A T Hillmer et al.   MOLECULAR PSYCHIATRY

Reconceptualization of translocator protein as a biomarker of neuroinflammation in psychiatry

(2017) T Notter et al.   MOLECULAR PSYCHIATRY

Neurochemical and metabolic effects of acute and chronic alcohol in the human brain: Studies with positron emission tomography

(2017) Nora D. Volkow et al.   NEUROPHARMACOLOGY

The role of neuroimmune signaling in alcoholism

(2017) Fulton T. Crews et al.   NEUROPHARMACOLOGY

Chronic ethanol intake induces partial microglial activation that is not reversed by long-term ethanol withdrawal in the rat hippocampal formation

(2017) Catarina Cruz et al.   NEUROTOXICOLOGY

Decreased hippocampal translocator protein (18 kDa) expression in alcohol dependence: a [11C]PBR28 PET study

(2017) N J Kalk et al.   Translational Psychiatry

Translocator Protein 18 kDa (TSPO): An Old Protein with New Functions?

(2016) Fei Li et al.   BIOCHEMISTRY

IL-1 receptor signaling in the basolateral amygdala modulates binge-like ethanol consumption in male C57BL/6J mice

(2016) S. Alex Marshall et al.   BRAIN BEHAVIOR AND IMMUNITY

Pharmacokinetic Analysis of 11C-PBR28 in the Rat Model of Herpes Encephalitis: Comparison with (R)-11C-PK11195

(2016) A. Parente et al.   JOURNAL OF NUCLEAR MEDICINE

Moderate alcohol consumption in chronic form enhances the synthesis of cholesterol and C-21 steroid hormones, while treatment with Tinospora cordifolia modulate these events in men

(2016) Suman Kumari et al.   STEROIDS

Sigma-2 receptor binding is decreased in female, but not male, APP/PS1 mice

(2015) Kristoffer Sahlholm et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Glucocorticoid receptor antagonism decreases alcohol seeking in alcohol-dependent individuals

(2015) Leandro F. Vendruscolo et al.   JOURNAL OF CLINICAL INVESTIGATION

Alcohol Decreases Baseline Brain Glucose Metabolism More in Heavy Drinkers Than Controls But Has No Effect on Stimulation-Induced Metabolic Increases

(2015) N. D. Volkow et al.   JOURNAL OF NEUROSCIENCE

Differential Roles of M1 and M2 Microglia in Neurodegenerative Diseases

(2015) Yu Tang et al.   MOLECULAR NEUROBIOLOGY

DAT isn’t all that: cocaine reward and reinforcement require Toll-like receptor 4 signaling

(2015) A L Northcutt et al.   MOLECULAR PSYCHIATRY

Decreased gray matter volume in inferior frontal gyrus is related to stop-signal task performance in alcohol-dependent patients

(2015) Corinde E. Wiers et al.   PSYCHIATRY RESEARCH-NEUROIMAGING

Cerebrospinal Fluid Monocyte Chemoattractant Protein-1 in Alcoholics: Support for a Neuroinflammatory Model of Chronic Alcoholism

(2014) John C. Umhau et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Regional brain distribution of translocator protein using [11C]DPA-713 PET in individuals infected with HIV

(2014) Jennifer M. Coughlin et al.   JOURNAL OF NEUROVIROLOGY

Detection of Microglial Activation in an Acute Model of Neuroinflammation Using PET and Radiotracers 11C-(R)-PK11195 and 18F-GE-180

(2014) A. M. Dickens et al.   JOURNAL OF NUCLEAR MEDICINE

Alcohol and adult hippocampal neurogenesis: Promiscuous drug, wanton effects

(2014) Chelsea R. Geil et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Operant alcohol self-administration in dependent rats: Focus on the vapor model

(2013) Leandro F. Vendruscolo et al.   ALCOHOL

PDT-induced epigenetic changes in the mouse cerebral cortex: A protein microarray study

(2013) S.V. Demyanenko et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Microglial activation is not equivalent to neuroinflammation in alcohol-induced neurodegeneration: The importance of microglia phenotype

(2013) S. Alex Marshall et al.   NEUROBIOLOGY OF DISEASE

Microglia: New Roles for the Synaptic Stripper

(2013) Helmut Kettenmann et al.   NEURON

Cognitive functions in abstinent alcohol-dependent patients

(2012) Maciej Kopera et al.   ALCOHOL

High Mobility Group Box 1/Toll-like Receptor Danger Signaling Increases Brain Neuroimmune Activation in Alcohol Dependence

(2012) Fulton T. Crews et al.   BIOLOGICAL PSYCHIATRY

Reactive Astrocytes Overexpress TSPO and Are Detected by TSPO Positron Emission Tomography Imaging

(2012) S. Lavisse et al.   JOURNAL OF NEUROSCIENCE

Endotoxin-induced systemic inflammation activates microglia: [11C]PBR28 positron emission tomography in nonhuman primates

(2012) Jonas Hannestad et al.   NEUROIMAGE

Reduced Cortical Thickness in Abstinent Alcoholics and Association with Alcoholic Behavior

(2011) Catherine B. Fortier et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

An 18-kDa Translocator Protein (TSPO) Polymorphism Explains Differences in Binding Affinity of the PET Radioligand PBR28

(2011) David R Owen et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Two Binding Sites for [3H]PBR28 in Human Brain: Implications for TSPO PET Imaging of Neuroinflammation

(2010) David R Owen et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Pivotal Role of TLR4 Receptors in Alcohol-Induced Neuroinflammation and Brain Damage

(2010) S. Alfonso-Loeches et al.   JOURNAL OF NEUROSCIENCE

In vivo binding of protoporphyrin IX to rat translocator protein imaged with positron emission tomography

(2010) Harushige Ozaki et al.   SYNAPSE

Chronic Alcohol Consumption Disrupted Cholesterol Homeostasis in Rats: Down-Regulation of Low-Density Lipoprotein Receptor and Enhancement of Cholesterol Biosynthesis Pathway in the Liver

(2009) Zhigang Wang et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Neuro-inflammation induced in the hippocampus of ‘binge drinking’ rats may be mediated by elevated extracellular glutamate content

(2009) Roberta J. Ward et al.   JOURNAL OF NEUROCHEMISTRY

Alcohol-related dementia: a 21st-century silent epidemic?

(2008) Susham Gupta et al.   BRITISH JOURNAL OF PSYCHIATRY

Increased systemic and brain cytokine production and neuroinflammation by endotoxin following ethanol treatment

(2008) Liya Qin et al.   Journal of Neuroinflammation

Macrophage-induced neurotoxicity is mediated by glutamate and attenuated by glutaminase inhibitors and gap junction inhibitors

(2008) Izumi Yawata et al.   LIFE SCIENCES

Translocator protein 18 kDa (TSPO): Molecular sensor of brain injury and repair

(2008) Ming-Kai Chen et al.   PHARMACOLOGY & THERAPEUTICS

Increased MCP-1 and microglia in various regions of the human alcoholic brain

(2007) Jun He et al.   EXPERIMENTAL NEUROLOGY