Metabolic pathways of lung inflammation revealed by high-resolution metabolomics (HRM) of H1N1 influenza virus infection in mice

Plasma Biomarkers of Inflammation, the Kynurenine Pathway, and Risks of All-Cause, Cancer, and Cardiovascular Disease Mortality

(2016) Hui Zuo et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Adenine Inhibits TNF-α Signaling in Intestinal Epithelial Cells and Reduces Mucosal Inflammation in a Dextran Sodium Sulfate-Induced Colitis Mouse Model

(2016) Toshihiko Fukuda et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Vitamin D3 alters microglia immune activation by an IL-10 dependent SOCS3 mechanism

(2016) Mandy Boontanrart et al.   JOURNAL OF NEUROIMMUNOLOGY

Deployment-Associated Exposure Surveillance With High-Resolution Metabolomics

(2016) Douglas I. Walker et al.   JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL MEDICINE

Metabolic Pathways and Networks Associated With Tobacco Use in Military Personnel

(2016) Dean P. Jones et al.   JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL MEDICINE

CARD9 impacts colitis by altering gut microbiota metabolism of tryptophan into aryl hydrocarbon receptor ligands

(2016) Bruno Lamas et al.   NATURE MEDICINE

Combined virus-like particle and fusion protein-encoding DNA vaccination of cotton rats induces protection against respiratory syncytial virus without causing vaccine-enhanced disease

(2016) Hye Suk Hwang et al.   VIROLOGY

The Influenza Virus H5N1 Infection Can Induce ROS Production for Viral Replication and Host Cell Death in A549 Cells Modulated by Human Cu/Zn Superoxide Dismutase (SOD1) Overexpression

(2016) Xian Lin et al.   Viruses-Basel

Metabolomics Investigation Reveals Metabolite Mediators Associated with Acute Lung Injury and Repair in a Murine Model of Influenza Pneumonia

(2016) Liang Cui et al.   Scientific Reports

Vitamin D and the Immune System

(2016) Cynthia Aranow   JOURNAL OF INVESTIGATIVE MEDICINE

Disturbed flow induces systemic changes in metabolites in mouse plasma: a metabolomics study using ApoE−/− mice with partial carotid ligation

(2015) Young-Mi Go et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

RNAseq expression analysis of resistant and susceptible mice after influenza A virus infection identifies novel genes associated with virus replication and important for host resistance to infection

(2015) Esther Wilk et al.   BMC GENOMICS

What is the tryptophan kynurenine pathway and why is it important to neurotherapeutics?

(2015) Ian Davis et al.   Expert Review of Neurotherapeutics

Tryptophan-kynurenine pathway is dysregulated in inflammation and immune activation

(2015) Ming-Hui Zou   Frontiers in Bioscience-Landmark

Emerging biology of sphingosine-1-phosphate: its role in pathogenesis and therapy

(2015) Richard L. Proia et al.   JOURNAL OF CLINICAL INVESTIGATION

Obesity Increases Mortality and Modulates the Lung Metabolome during Pandemic H1N1 Influenza Virus Infection in Mice

(2015) J. Justin Milner et al.   JOURNAL OF IMMUNOLOGY

Acute Respiratory Distress Syndrome: Role of Oleic Acid-Triggered Lung Injury and Inflammation

(2015) Cassiano Felippe Gonçalves-de-Albuquerque et al.   MEDIATORS OF INFLAMMATION

NF-κB increased expression of 17β-hydroxysteroid dehydrogenase 4 promotes HepG2 proliferation via inactivating estradiol

(2015) Xin Lu et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Reference Standardization for Mass Spectrometry and High-resolution Metabolomics Applications to Exposome Research

(2015) Young-Mi Go et al.   TOXICOLOGICAL SCIENCES

A systems approach to understanding human rhinovirus and influenza virus infection

(2015) Taek-Kyun Kim et al.   VIROLOGY

What is the tryptophan kynurenine pathway and why is it important to neurotherapeutics?

(2015) Ian Davis et al.   Expert Review of Neurotherapeutics

Modulating the Innate Immune Response to Influenza A Virus: Potential Therapeutic Use of Anti-Inflammatory Drugs

(2015) Irene Ramos et al.   Frontiers in Immunology

Metabolic Characterization of the Common Marmoset (Callithrix jacchus)

(2015) Young-Mi Go et al.   PLoS One

Metabolomics of Bronchoalveolar Lavage Differentiate Healthy HIV-1-Infected Subjects from Controls

(2014) Sushma K. Cribbs et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

Bile Acid Aspiration Associated With Lung Chemical Profile Linked to Other Biomarkers of Injury After Lung Transplantation

(2014) D. C. Neujahr et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Co-immunization with virus-like particle and DNA vaccines induces protection against respiratory syncytial virus infection and bronchiolitis

(2014) Hye Suk Hwang et al.   ANTIVIRAL RESEARCH

Maternal antibodies by passive immunization with formalin inactivated respiratory syncytial virus confer protection without vaccine-enhanced disease

(2014) Young-Man Kwon et al.   ANTIVIRAL RESEARCH

Identifying Small Molecules via High Resolution Mass Spectrometry: Communicating Confidence

(2014) Emma L. Schymanski et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

De novo synthesize of bile acids in pulmonary arterial hypertension lung

(2014) Yidan D. Zhao et al.   Metabolomics

Vitamin D3 metabolite calcidiol primes human dendritic cells to promote the development of immunomodulatory IL-10-producing T cells

(2014) Ghaith Bakdash et al.   VACCINE

xMSanalyzer: automated pipeline for improved feature detection and downstream analysis of large-scale, non-targeted metabolomics data

(2013) Karan Uppal et al.   BMC BIOINFORMATICS

Lipidomic Profiling of Influenza Infection Identifies Mediators that Induce and Resolve Inflammation

(2013) Vincent C. Tam et al.   CELL

A Systems Analysis Identifies a Feedforward Inflammatory Circuit Leading to Lethal Influenza Infection

(2013) Marlène Brandes et al.   CELL

Selective Metabolism of Hypothiocyanous Acid by Mammalian Thioredoxin Reductase Promotes Lung Innate Immunity and Antioxidant Defense

(2013) Joshua D. Chandler et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Predicting Network Activity from High Throughput Metabolomics

(2013) Shuzhao Li et al.   PLoS Computational Biology

IL-10 Regulates Viral Lung Immunopathology during Acute Respiratory Syncytial Virus Infection in Mice

(2012) Jens Loebbermann et al.   PLoS One

Systems approaches to influenza-virus host interactions and the pathogenesis of highly virulent and pandemic viruses

(2012) Marcus J. Korth et al.   SEMINARS IN IMMUNOLOGY

Visualising associations between paired ‘omics’ data sets

(2012) Ignacio González et al.   BioData Mining

Conserved host response to highly pathogenic avian influenza virus infection in human cell culture, mouse and macaque model systems

(2011) Jason E McDermott et al.   BMC Systems Biology

The Quorum-Sensing Molecules Farnesol/Homoserine Lactone and Dodecanol Operate via Distinct Modes of Action in Candida albicans

(2011) Rebecca A. Hall et al.   EUKARYOTIC CELL

High-performance metabolic profiling with dual chromatography-Fourier-transform mass spectrometry (DC-FTMS) for study of the exposome

(2011) Quinlyn A. Soltow et al.   Metabolomics

Increased Inflammatory Signaling and Lethality of Influenza H1N1 by Nuclear Thioredoxin-1

(2011) Young-Mi Go et al.   PLoS One

IFN-γ Treatment at Early Stages of Influenza Virus Infection Protects Mice from Death in a NK Cell-Dependent Manner

(2010) Ido D. Weiss et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Virus–host cell interactions in vaccine production cell lines infected with different human influenza A virus variants: A proteomic approach

(2010) Diana Vester et al.   Journal of Proteomics

Virus-Like Particle Vaccine Protects against 2009 H1N1 Pandemic Influenza Virus in Mice

(2010) Fu-Shi Quan et al.   PLoS One

Inflammation-associated depression: From serotonin to kynurenine

(2010) Robert Dantzer et al.   PSYCHONEUROENDOCRINOLOGY

GC/MS-based metabolomics reveals fatty acid biosynthesis and cholesterol metabolism in cell lines infected with influenza A virus

(2010) Shuhai Lin et al.   TALANTA

integrOmics: an R package to unravel relationships between two omics datasets

(2009) Kim-Anh Lê Cao et al.   BIOINFORMATICS

Activation of Central Nervous System Inflammatory Pathways by Interferon-Alpha: Relationship to Monoamines and Depression

(2008) Charles L. Raison et al.   BIOLOGICAL PSYCHIATRY

Lack of antibody affinity maturation due to poor Toll-like receptor stimulation leads to enhanced respiratory syncytial virus disease

(2008) Maria Florencia Delgado et al.   NATURE MEDICINE