The NRF2 knockout rat: a new animal model to study endothelial dysfunction, oxidant stress, and microvascular rarefaction

Low-Dose Angiotensin II Infusion Restores Vascular Function in Cerebral Arteries of High Salt-Fed Rats by Increasing Copper/Zinc Superoxide Dimutase Expression

(2013) M. J. Durand et al.   AMERICAN JOURNAL OF HYPERTENSION

Reduced angiotensin II levels cause generalized vascular dysfunction via oxidant stress in hamster cheek pouch arterioles

(2013) Jessica R.C. Priestley et al.   MICROVASCULAR RESEARCH

Vascular endothelial growth factor-A signaling in bone marrow-derived endothelial progenitor cells exposed to hypoxic stress

(2013) Brian R. Hoffmann et al.   PHYSIOLOGICAL GENOMICS

Efficacy of vitamin and antioxidant supplements in prevention of cardiovascular disease: systematic review and meta-analysis of randomised controlled trials

(2013) S.-K. Myung et al.   BMJ-British Medical Journal

Polymorphisms in the transcription factor NRF2 and forearm vasodilator responses in humans

(2012) Ewa D. Marczak et al.   Pharmacogenetics and Genomics

Upregulation of Nrf2 Expression in Non-Alcoholic Fatty Liver and Steatohepatitis

(2011) Weihua Xu et al.   HEPATO-GASTROENTEROLOGY

Creation and Characterization of a Renin Knockout Rat

(2011) Carol Moreno et al.   HYPERTENSION

Targeting the Nrf2-Keap1 antioxidant defence pathway for neurovascular protection in stroke

(2011) Alessio Alfieri et al.   JOURNAL OF PHYSIOLOGY-LONDON

Oxidative stress in health and disease: The therapeutic potential of Nrf2 activation

(2011) Brooks M. Hybertson et al.   MOLECULAR ASPECTS OF MEDICINE

Angiotensin-(1-7) and low-dose angiotensin II infusion reverse salt-induced endothelial dysfunction via different mechanisms in rat middle cerebral arteries

(2010) Matthew J. Durand et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Global Downstream Pathway Analysis Reveals a Dependence of Oncogenic NF-E2-Related Factor 2 Mutation on the mTOR Growth Signaling Pathway

(2010) T. Shibata et al.   CANCER RESEARCH

Gene targeting in the rat: advances and opportunities

(2010) Howard J. Jacob et al.   TRENDS IN GENETICS

Angiotensin II maintains cerebral vascular relaxation via EGF receptor transactivation and ERK1/2

(2009) Scott T. McEwen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Redox-Dependent Mechanisms in Coronary Collateral Growth: The “Redox Window” Hypothesis

(2009) June Yun et al.   ANTIOXIDANTS & REDOX SIGNALING

Time-Course and Mechanisms of Restored Vascular Relaxation by Reduced Salt Intake and Angiotensin II Infusion in Rats Fed a High-Salt Diet

(2009) Scott T. McEwen et al.   MICROCIRCULATION

Effect of ANG II on endothelial cell apoptosis and survival and its impact on skeletal muscle angiogenesis after electrical stimulation

(2008) Micheline M. de Resende et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Decline in NRF2-regulated Antioxidants in Chronic Obstructive Pulmonary Disease Lungs Due to Loss of Its Positive Regulator, DJ-1

(2008) Deepti Malhotra et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Down-Regulated NF-E2–Related Factor 2 in Pulmonary Macrophages of Aged Smokers and Patients with Chronic Obstructive Pulmonary Disease

(2008) Masaru Suzuki et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Loss of Keap1 Function Activates Nrf2 and Provides Advantages for Lung Cancer Cell Growth

(2008) T. Ohta et al.   CANCER RESEARCH

Adverse Cardiovascular Effects of Acute Salt Loading in Young Normotensive Individuals

(2008) Nikolaos Tzemos et al.   HYPERTENSION

Nrf2 Activation in Astrocytes Protects against Neurodegeneration in Mouse Models of Familial Amyotrophic Lateral Sclerosis

(2008) M. R. Vargas et al.   JOURNAL OF NEUROSCIENCE

Cancer related mutations in NRF2 impair its recognition by Keap1-Cul3 E3 ligase and promote malignancy

(2008) T. Shibata et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Mechanistic Basis for the Disparate Effects of Angiotensin II on Coronary Collateral Growth

(2007) Ryan Reed et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY