Eravacycline: A Review in Complicated Intra-Abdominal Infections

Evaluation of the In Vitro Activity of Eravacycline against a Broad Spectrum of Recent Clinical Anaerobic Isolates

(2018) David R. Snydman et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

In vitro activity of eravacycline against 2213 Gram-negative and 2424 Gram-positive bacterial pathogens isolated in Canadian hospital laboratories: CANWARD surveillance study 2014–2015

(2018) George G. Zhanel et al.   DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE

Assessment of in vivo efficacy of eravacycline against Enterobacteriaceae exhibiting various resistance mechanisms: a dose-ranging study and pharmacokinetic/pharmacodynamic analysis

(2018) Abrar K. Thabit et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

In-vitro activity of the novel fluorocycline eravacycline against carbapenem non-susceptible Acinetobacter baumannii

(2018) Harald Seifert et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Randomized, Double-Blind, Placebo-Controlled Studies of the Safety and Pharmacokinetics of Single and Multiple Ascending Doses of Eravacycline

(2018) Joseph V. Newman et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

The Surgical Infection Society Revised Guidelines on the Management of Intra-Abdominal Infection

(2017) John E. Mazuski et al.   Surgical Infections

Assessing the Efficacy and Safety of Eravacycline vs Ertapenem in Complicated Intra-abdominal Infections in the Investigating Gram-Negative Infections Treated With Eravacycline (IGNITE 1) Trial

(2017) Joseph Solomkin et al.   JAMA Surgery

The management of intra-abdominal infections from a global perspective: 2017 WSES guidelines for management of intra-abdominal infections

(2017) Massimo Sartelli et al.   World Journal of Emergency Surgery

Antibacterial Efficacy of EravacyclineIn Vivoagainst Gram-Positive and Gram-Negative Organisms

(2016) Marguerite L. Monogue et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Eravacycline Is Active against Bacterial Isolates Expressing the Polymyxin Resistance Genemcr-1

(2016) Corey Fyfe et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

In VitroActivity of Eravacycline against Carbapenem-Resistant Enterobacteriaceae and Acinetobacter baumannii

(2016) David M. Livermore et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Review of Eravacycline, a Novel Fluorocycline Antibacterial Agent

(2016) George G. Zhanel et al.   DRUGS

Antimicrobials: a global alliance for optimizing their rational use in intra-abdominal infections (AGORA)

(2016) Massimo Sartelli et al.   World Journal of Emergency Surgery

Eravacycline (TP-434) Is Efficacious in Animal Models of Infection

(2015) Trudy H. Grossman et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Antimicrobial resistance: a global multifaceted phenomenon

(2015) Francesca Prestinaci et al.   Pathogens and Global Health

Activity of Eravacycline against Enterobacteriaceae and Acinetobacter baumannii, Including Multidrug-Resistant Isolates, from New York City

(2014) Marie Abdallah et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Tetracycline antibiotics and resistance mechanisms

(2014) Fabian Nguyen et al.   BIOLOGICAL CHEMISTRY

Multidrug-resistant and extensively drug-resistant Gram-negative pathogens: current and emerging therapeutic approaches

(2014) Ilias Karaiskos et al.   EXPERT OPINION ON PHARMACOTHERAPY

Phase 2, Randomized, Double-Blind Study of the Efficacy and Safety of Two Dose Regimens of Eravacycline versus Ertapenem for Adult Community-Acquired Complicated Intra-Abdominal Infections

(2013) Joseph S. Solomkin et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Antibacterial Activity of Eravacycline (TP-434), a Novel Fluorocycline, against Hospital and Community Pathogens

(2013) J. A. Sutcliffe et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Target- and Resistance-Based Mechanistic Studies with TP-434, a Novel Fluorocycline Antibiotic

(2012) Trudy H. Grossman et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Fluorocyclines. 2. Optimization of the C-9 Side-Chain for Antibacterial Activity and Oral Efficacy

(2011) Roger B. Clark et al.   JOURNAL OF MEDICINAL CHEMISTRY

Fluorocyclines. 1. 7-Fluoro-9-pyrrolidinoacetamido-6-demethyl-6-deoxytetracycline: A Potent, Broad Spectrum Antibacterial Agent

(2011) Xiao-Yi Xiao et al.   JOURNAL OF MEDICINAL CHEMISTRY