Sirt3 protects mitochondrial DNA damage and blocks the development of doxorubicin-induced cardiomyopathy in mice

Regulation of the mPTP by SIRT3-mediated deacetylation of CypD at lysine 166 suppresses age-related cardiac hypertrophy

(2016) Angela V. Hafner et al.   Aging-US

Sirtuin-3 (SIRT3) Protein Attenuates Doxorubicin-induced Oxidative Stress and Improves Mitochondrial Respiration in H9c2 Cardiomyocytes

(2015) Kyle G. Cheung et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Honokiol blocks and reverses cardiac hypertrophy in mice by activating mitochondrial Sirt3

(2015) Vinodkumar B. Pillai et al.   Nature Communications

Cardiotoxicity of doxorubicin is mediated through mitochondrial iron accumulation

(2014) Yoshihiko Ichikawa et al.   JOURNAL OF CLINICAL INVESTIGATION

SIRT3 Deacetylates and Activates OPA1 To Regulate Mitochondrial Dynamics during Stress

(2013) Sadhana A. Samant et al.   MOLECULAR AND CELLULAR BIOLOGY

The Maintenance of Mitochondrial DNA Integrity--Critical Analysis and Update

(2013) M. Alexeyev et al.   Cold Spring Harbor Perspectives in Biology

Interaction of Sirt3 with OGG1 contributes to repair of mitochondrial DNA and protects from apoptotic cell death under oxidative stress

(2013) Y Cheng et al.   Cell Death & Disease

Regulation of DNA glycosylases and their role in limiting disease

(2012) Harini Sampath et al.   FREE RADICAL RESEARCH

SIRT3 Protein Deacetylates Isocitrate Dehydrogenase 2 (IDH2) and Regulates Mitochondrial Redox Status

(2012) Wei Yu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Calorie Restriction and SIRT3 Trigger Global Reprogramming of the Mitochondrial Protein Acetylome

(2012) Alexander S. Hebert et al.   MOLECULAR CELL

Identification of the molecular basis of doxorubicin-induced cardiotoxicity

(2012) Sui Zhang et al.   NATURE MEDICINE

8-Oxoguanine DNA Glycosylase (OGG1) Deficiency Increases Susceptibility to Obesity and Metabolic Dysfunction

(2012) Harini Sampath et al.   PLoS One

Metabolic regulation by SIRT3: implications for tumorigenesis

(2012) Lydia W.S. Finley et al.   TRENDS IN MOLECULAR MEDICINE

Characterization of DNA with an 8-oxoguanine modification

(2011) Sreelekha K. Singh et al.   NUCLEIC ACIDS RESEARCH

Endurance exercise rescues progeroid aging and induces systemic mitochondrial rejuvenation in mtDNA mutator mice

(2011) A. Safdar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Calorie Restriction Reduces Oxidative Stress by SIRT3-Mediated SOD2 Activation

(2010) Xiaolei Qiu et al.   Cell Metabolism

DNA Topoisomerases and Their Poisoning by Anticancer and Antibacterial Drugs

(2010) Yves Pommier et al.   CHEMISTRY & BIOLOGY

8-Oxo-7,8-dihydroguanine: Links to gene expression, aging, and defense against oxidative stress

(2010) Zsolt Radak et al.   FREE RADICAL BIOLOGY AND MEDICINE

Limitations in doxorubicin production from Streptomyces peucetius

(2010) Sailesh Malla et al.   MICROBIOLOGICAL RESEARCH

Sirt3-Mediated Deacetylation of Evolutionarily Conserved Lysine 122 Regulates MnSOD Activity in Response to Stress

(2010) Randa Tao et al.   MOLECULAR CELL

Age-Dependent Down-Regulation of Mitochondrial 8-Oxoguanine DNA Glycosylase in SAM-P/8 Mouse Brain and Its Effect on Brain Aging

(2009) Feng Tian et al.   REJUVENATION RESEARCH

SIRT3 Is a Stress-Responsive Deacetylase in Cardiomyocytes That Protects Cells from Stress-Mediated Cell Death by Deacetylation of Ku70

(2008) N. R. Sundaresan et al.   MOLECULAR AND CELLULAR BIOLOGY