TAM receptor tyrosine kinase function and the immunopathology of liver disease

Galectin-3 is expressed in the myocardium very early post–myocardial infarction

(2015) Satwat Hashmi et al.   CARDIOVASCULAR PATHOLOGY

Galectin-3 and post-myocardial infarction cardiac remodeling

(2015) Wouter C. Meijers et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Patients With Acute-on-Chronic Liver Failure Have Increased Numbers of Regulatory Immune Cells Expressing the Receptor Tyrosine Kinase MERTK

(2015) Christine Bernsmeier et al.   GASTROENTEROLOGY

Postmortem serum protein growth arrest-specific 6 levels in sepsis-related deaths

(2015) Cristian Palmiere et al.   INTERNATIONAL JOURNAL OF LEGAL MEDICINE

Gas6/Axl pathway is activated in chronic liver disease and its targeting reduces fibrosis via hepatic stellate cell inactivation

(2015) Cristina Bárcena et al.   JOURNAL OF HEPATOLOGY

The Mechanism of Interferon Refractoriness During Hepatitis C Virus Infection and Its Reversal with a Peroxisome Proliferator-Activated Receptor α Agonist

(2015) Scott A. Read et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Hepatitis C Virus Driven AXL Expression Suppresses the Hepatic Type I Interferon Response

(2015) Scott A. Read et al.   PLoS One

Axl as a mediator of cellular growth and survival

(2015) Haley Axelrod et al.   Oncotarget

TAM receptors, Gas6, and protein S: roles in inflammation and hemostasis

(2014) J. H. M. van der Meer et al.   BLOOD

Receptor Tyrosine Kinases, TYRO3, AXL, and MER, Demonstrate Distinct Patterns and Complex Regulation of Ligand-induced Activation

(2014) Wen-I Tsou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Axl Receptor Blockade Ameliorates Pulmonary Pathology Resulting from Primary Viral Infection and Viral Exacerbation of Asthma

(2014) T. Shibata et al.   JOURNAL OF IMMUNOLOGY

The E3 ligase Cbl-b and TAM receptors regulate cancer metastasis via natural killer cells

(2014) Magdalena Paolino et al.   NATURE

Diversification of TAM receptor tyrosine kinase function

(2014) Anna Zagórska et al.   NATURE IMMUNOLOGY

Cellular Mechanisms of Tissue Fibrosis. 5. Novel insights into liver fibrosis

(2013) Ariane Mallat et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Immunodominance and functional alterations of tumor-associated antigen-specific CD8+T-cell responses in hepatocellular carcinoma

(2013) Tobias Flecken et al.   HEPATOLOGY

T Cell-Derived Protein S Engages TAM Receptor Signaling in Dendritic Cells to Control the Magnitude of the Immune Response

(2013) Eugenio A. Carrera Silva et al.   IMMUNITY

Breakdown of immune homeostasis in the testis of mice lacking Tyro3, Axl and Mer receptor tyrosine kinases

(2013) Yue Zhang et al.   IMMUNOLOGY AND CELL BIOLOGY

MerTK inhibition in tumor leukocytes decreases tumor growth and metastasis

(2013) Rebecca S. Cook et al.   JOURNAL OF CLINICAL INVESTIGATION

TAM Receptors Affect Adult Brain Neurogenesis by Negative Regulation of Microglial Cell Activation

(2013) R. Ji et al.   JOURNAL OF IMMUNOLOGY

Development of a Spontaneous Liver Disease Resembling Autoimmune Hepatitis in Mice Lacking Tyro3, Axl and Mer Receptor Tyrosine Kinases

(2013) Nan Qi et al.   PLoS One

The TIM and TAM Families of Phosphatidylserine Receptors Mediate Dengue Virus Entry

(2012) Laurent Meertens et al.   Cell Host & Microbe

Efficient Clearance of Early Apoptotic Cells by Human Macrophages Requires M2c Polarization and MerTK Induction

(2012) G. Zizzo et al.   JOURNAL OF IMMUNOLOGY

Preventing cleavage of Mer promotes efferocytosis and suppresses acute lung injury in bleomycin treated mice

(2012) Ye-Ji Lee et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Gas6 deficiency prevents liver inflammation, steatohepatitis, and fibrosis in mice

(2011) Agnès Fourcot et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Epithelial cell-directed efferocytosis in the post-partum mammary gland is necessary for tissue homeostasis and future lactation

(2011) Melissa Sandahl et al.   BMC DEVELOPMENTAL BIOLOGY

Galectin-3 is a new MerTK-specific eat-me signal

(2011) Nora B. Caberoy et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Targeting Axl and Mer Kinases in Cancer

(2011) A. Verma et al.   MOLECULAR CANCER THERAPEUTICS

Cancer Immunoediting: Integrating Immunity's Roles in Cancer Suppression and Promotion

(2011) R. D. Schreiber et al.   SCIENCE

TAM receptor signaling and autoimmune disease

(2010) Carla V Rothlin et al.   CURRENT OPINION IN IMMUNOLOGY

Sertoli Cell-Initiated Testicular Innate Immune Response through Toll-Like Receptor-3 Activation Is Negatively Regulated by Tyro3, Axl, and Mer Receptors

(2010) Bing Sun et al.   ENDOCRINOLOGY

Growth arrest-specific protein 6 is hepatoprotective against murine ischemia/reperfusion injury

(2010) Laura Llacuna et al.   HEPATOLOGY

Find-me and eat-me signals in apoptotic cell clearance: progress and conundrums

(2010) Kodi S. Ravichandran   JOURNAL OF EXPERIMENTAL MEDICINE

Proinflammatory Clearance of Apoptotic Neutrophils Induces an IL-12lowIL-10high Regulatory Phenotype in Macrophages

(2010) A. A. Filardy et al.   JOURNAL OF IMMUNOLOGY

Impaired Apoptotic Cell Clearance in the Germinal Center by Mer-Deficient Tingible Body Macrophages Leads to Enhanced Antibody-Forming Cell and Germinal Center Responses

(2010) Z. S. M. Rahman et al.   JOURNAL OF IMMUNOLOGY

Differential expression of Axl in hepatocellular carcinoma and correlation with tumor lymphatic metastasis

(2010) Ling He et al.   MOLECULAR CARCINOGENESIS

Generation and phenotypic analysis of protein S-deficient mice

(2009) F. Saller et al.   BLOOD

Mer receptor tyrosine kinase is a novel therapeutic target in pediatric B-cell acute lymphoblastic leukemia

(2009) R. M. A. Linger et al.   BLOOD

Apoptotic Cells Promote Their Own Clearance and Immune Tolerance through Activation of the Nuclear Receptor LXR

(2009) Noelia A-Gonzalez et al.   IMMUNITY

Immune tolerance: What is unique about the liver

(2009) Gisa Tiegs et al.   JOURNAL OF AUTOIMMUNITY

Lack of Protein S in mice causes embryonic lethal coagulopathy and vascular dysgenesis

(2009) Tal Burstyn-Cohen et al.   JOURNAL OF CLINICAL INVESTIGATION

Receptor tyrosine kinase AXL is induced by chemotherapy drugs and overexpression of AXL confers drug resistance in acute myeloid leukemia

(2008) Chih-Chen Hong et al.   CANCER LETTERS

AXL Is a Potential Target for Therapeutic Intervention in Breast Cancer Progression

(2008) Y.-X. Zhang et al.   CANCER RESEARCH

Axl promotes cell invasion by inducing MMP-9 activity through activation of NF-κB and Brg-1

(2008) K-Y Tai et al.   ONCOGENE

Vaccinia Virus Uses Macropinocytosis and Apoptotic Mimicry to Enter Host Cells

(2008) J. Mercer et al.   SCIENCE