Nuclear factor-κB regulates the expression of multiple genes encoding liver transport proteins

Emerging roles of the corepressors NCoR1 and SMRT in homeostasis

(2013) A. Mottis et al.   GENES & DEVELOPMENT

SUMOylation of the Farnesoid X Receptor (FXR) Regulates the Expression of FXR Target Genes

(2013) Natarajan Balasubramaniyan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nuclear receptor co-repressors are required for the histone-deacetylase activity of HDAC3 in vivo

(2013) Seo-Hee You et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Histone H3K4 trimethylation by MLL3 as part of ASCOM complex is critical for NR activation of bile acid transporter genes and is downregulated in cholestasis

(2011) M. Ananthanarayanan et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Activation of bile salt nuclear receptor FXR is repressed by pro-inflammatory cytokines activating NF-κB signaling in the intestine

(2011) Raffaella M. Gadaleta et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

NF-κB, Inflammation, and Metabolic Disease

(2011) Rebecca G. Baker et al.   Cell Metabolism

Nuclear hormone receptor co-repressors: Structure and function

(2011) Peter J. Watson et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Hierarchies of NF-κB target-gene regulation

(2011) Stephen T Smale   NATURE IMMUNOLOGY

Principles of dimer-specific gene regulation revealed by a comprehensive characterization of NF-κB family DNA binding

(2011) Trevor Siggers et al.   NATURE IMMUNOLOGY

Regulation of FXR transcriptional activity in health and disease: Emerging roles of FXR cofactors and post-translational modifications

(2010) Jongsook Kim Kemper   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Genome-wide interrogation of hepatic FXR reveals an asymmetric IR-1 motif and synergy with LRH-1

(2010) Hansook Kim Chong et al.   NUCLEIC ACIDS RESEARCH

Organic Solute Transporter, OSTα-OSTβ: Its Role in Bile Acid Transport and Cholestasis

(2010) Carol Soroka et al.   SEMINARS IN LIVER DISEASE

Nuclear Receptor Regulation of the Adaptive Response of Bile Acid Transporters in Cholestasis

(2010) Martin Wagner et al.   SEMINARS IN LIVER DISEASE

Cooperative NCoR/SMRT interactions establish a corepressor-based strategy for integration of inflammatory and anti-inflammatory signaling pathways

(2009) S. Ghisletti et al.   GENES & DEVELOPMENT

Genome-wide tissue-specific farnesoid X receptor binding in mouse liver and intestine

(2009) Ann M. Thomas et al.   HEPATOLOGY

The Bile Acid Receptor FXR Is a Modulator of Intestinal Innate Immunity

(2009) P. Vavassori et al.   JOURNAL OF IMMUNOLOGY

Farnesoid X receptor antagonizes nuclear factor κB in hepatic inflammatory response

(2008) Yan-Dong Wang et al.   HEPATOLOGY

The p300 Acetylase Is Critical for Ligand-activated Farnesoid X Receptor (FXR) Induction of SHP

(2008) Sungsoon Fang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY