Plasma amino acid and metabolite signatures tracking diabetes progression in the UCD-T2DM rat model

Whey Protein Supplementation Does Not Alter Plasma Branched-Chained Amino Acid Profiles but Results in Unique Metabolomics Patterns in Obese Women Enrolled in an 8-Week Weight Loss Trial

(2015) Brian D Piccolo et al.   JOURNAL OF NUTRITION

Effect of Insulin Sensitizer Therapy on Amino Acids and Their Metabolites

(2015) Brian A. Irving et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Global Biochemical Profiling Identifies β-Hydroxypyruvate as a Potential Mediator of Type 2 Diabetes in Mice and Humans

(2014) Sheng Zhang et al.   DIABETES

1,5-Anhydroglucitol in Saliva Is a Noninvasive Marker of Short-Term Glycemic Control

(2014) Dennis O. Mook-Kanamori et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Metabolic profiling in diabetes

(2014) Karsten Suhre   JOURNAL OF ENDOCRINOLOGY

Serum and Adipose Tissue Amino Acid Homeostasis in the Metabolically Healthy Obese

(2014) Flavia Badoud et al.   JOURNAL OF PROTEOME RESEARCH

Branched-chain amino acids in metabolic signalling and insulin resistance

(2014) Christopher J. Lynch et al.   Nature Reviews Endocrinology

Improved Metabolic Health Alters Host Metabolism in Parallel with Changes in Systemic Xeno-Metabolites of Gut Origin

(2014) Caitlin Campbell et al.   PLoS One

Regulation of adipose branched-chain amino acid catabolism enzyme expression and cross-adipose amino acid flux in human obesity

(2013) Denise E. Lackey et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Biomarkers for Type 2 Diabetes and Impaired Fasting Glucose Using a Nontargeted Metabolomics Approach

(2013) C. Menni et al.   DIABETES

2-Aminoadipic acid is a biomarker for diabetes risk

(2013) Thomas J. Wang et al.   JOURNAL OF CLINICAL INVESTIGATION

Branched chain and aromatic amino acids change acutely following two medical therapies for type 2 diabetes mellitus

(2013) Geoffrey A. Walford et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Leucine and Protein Metabolism in Obese Zucker Rats

(2013) Pengxiang She et al.   PLoS One

Increased Plasma Citrulline in Mice Marks Diet-Induced Obesity and May Predict the Development of the Metabolic Syndrome

(2013) Manuela Sailer et al.   PLoS One

Interplay between Lipids and Branched-Chain Amino Acids in Development of Insulin Resistance

(2012) Christopher B. Newgard   Cell Metabolism

Identification of Serum Metabolites Associated With Risk of Type 2 Diabetes Using a Targeted Metabolomic Approach

(2012) A. Floegel et al.   DIABETES

Early Metabolic Markers of the Development of Dysglycemia and Type 2 Diabetes and Their Physiological Significance

(2012) E. Ferrannini et al.   DIABETES

Circulating Metabolite Predictors of Glycemia in Middle-Aged Men and Women

(2012) P. Wurtz et al.   DIABETES CARE

Novel biomarkers for pre-diabetes identified by metabolomics

(2012) Rui Wang-Sattler et al.   Molecular Systems Biology

Emerging Perspectives on Essential Amino Acid Metabolism in Obesity and the Insulin-Resistant State

(2012) Sean H. Adams   Advances in Nutrition

Branched-chain amino acid levels are associated with improvement in insulin resistance with weight loss

(2011) S. H. Shah et al.   DIABETOLOGIA

Metabolite profiles and the risk of developing diabetes

(2011) Thomas J Wang et al.   NATURE MEDICINE

Differential Metabolic Impact of Gastric Bypass Surgery Versus Dietary Intervention in Obese Diabetic Subjects Despite Identical Weight Loss

(2011) B. Laferrere et al.   Science Translational Medicine

Regulation of hepatic branched-chain α-keto acid dehydrogenase kinase in a rat model for type 2 diabetes mellitus at different stages of the disease

(2010) Masao Doisaki et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

α-Hydroxybutyrate Is an Early Biomarker of Insulin Resistance and Glucose Intolerance in a Nondiabetic Population

(2010) Walter E. Gall et al.   PLoS One

Metabolic Footprint of Diabetes: A Multiplatform Metabolomics Study in an Epidemiological Setting

(2010) Karsten Suhre et al.   PLoS One

Plasma Metabolomic Profiles Reflective of Glucose Homeostasis in Non-Diabetic and Type 2 Diabetic Obese African-American Women

(2010) Oliver Fiehn et al.   PLoS One

Clinical Application of Incretin-Based Therapy: Therapeutic Potential, Patient Selection and Clinical Use

(2009) David M. Kendall et al.   AMERICAN JOURNAL OF MEDICINE

Metabonomics research of diabetic nephropathy and type 2 diabetes mellitus based on UPLC–oaTOF-MS system

(2009) Jie Zhang et al.   ANALYTICA CHIMICA ACTA

A Branched-Chain Amino Acid-Related Metabolic Signature that Differentiates Obese and Lean Humans and Contributes to Insulin Resistance

(2009) Christopher B. Newgard et al.   Cell Metabolism

Plasma Acylcarnitine Profiles Suggest Incomplete Long-Chain Fatty Acid β-Oxidation and Altered Tricarboxylic Acid Cycle Activity in Type 2 Diabetic African-American Women

(2009) Sean H. Adams et al.   JOURNAL OF NUTRITION

Metabonomic Variations in the Drug-Treated Type 2 Diabetes Mellitus Patients and Healthy Volunteers

(2009) Yuqian Bao et al.   JOURNAL OF PROTEOME RESEARCH

Mechanisms of human insulin resistance and thiazolidinedione-mediated insulin sensitization

(2009) D. D. Sears et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Development and characterization of a novel rat model of type 2 diabetes mellitus: the UC Davis type 2 diabetes mellitus UCD-T2DM rat

(2008) Bethany P. Cummings et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Assessment of PLSDA cross validation

(2008) Johan A. Westerhuis et al.   Metabolomics