CFTR silencing in pancreatic β-cells reveals a functional impact on glucose-stimulated insulin secretion and oxidative stress response

Glycaemic regulation and insulin secretion are abnormal in cystic fibrosis pigs despite sparing of islet cell mass

(2015) Aliye Uc et al.   CLINICAL SCIENCE

CFTR and Anoctamin 1 (ANO1) contribute to cAMP amplified exocytosis and insulin secretion in human and murine pancreatic beta-cells

(2014) Anna Edlund et al.   BMC Medicine

Revisiting CFTR inhibition: a comparative study of CFTRinh-172 and GlyH-101 inhibitors

(2014) N Melis et al.   BRITISH JOURNAL OF PHARMACOLOGY

Evidence for a Causal Relationship Between Early Exocrine Pancreatic Disease and Cystic Fibrosis–Related Diabetes: A Mendelian Randomization Study

(2014) David Soave et al.   DIABETES

Glucose-induced electrical activities and insulin secretion in pancreatic islet β-cells are modulated by CFTR

(2014) Jing Hui Guo et al.   Nature Communications

Insulin secretion improves in cystic fibrosis following ivacaftor correction of CFTR: a small pilot study

(2013) Melena D Bellin et al.   PEDIATRIC DIABETES

Iron-Ascorbate-Mediated Lipid Peroxidation Causes Epigenetic Changes in the Antioxidant Defense in Intestinal Epithelial Cells: Impact on Inflammation

(2013) Sabrina Yara et al.   PLoS One

CFTR Is Involved in the Fine Tuning of Intracellular Redox Status

(2012) Christophe Duranton et al.   AMERICAN JOURNAL OF PATHOLOGY

S-Glutathionylation signaling in cell biology: Progress and prospects

(2012) Anna Pastore et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Chloride transport in functionally active phagosomes isolated from Human neutrophils

(2012) Martha L. Aiken et al.   FREE RADICAL BIOLOGY AND MEDICINE

Parathyroid hormone (PTH) rapidly enhances CFTR-mediated HCO3− secretion in intestinal epithelium-like Caco-2 monolayer: a novel ion regulatory action of PTH

(2011) Suparerk Laohapitakworn et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Update in Cystic Fibrosis 2010

(2011) Peter J. Mogayzel et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Recommendations for the classification of diseases as CFTR-related disorders

(2011) C. Bombieri et al.   Journal of Cystic Fibrosis

Persistent fat malabsorption in cystic fibrosis; lessons from patients and mice

(2011) M. Wouthuyzen-Bakker et al.   Journal of Cystic Fibrosis

Self-inducible secretion of glucagon-like peptide-1 (GLP-1) that allows MIN6 cells to maintain insulin secretion and insure cell survival

(2011) Koji Nakashima et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Cystic Fibrosis Related Diabetes (CFRD)-The End Stage of Progressive Insulin Deficiency

(2011) Shihab Hameed et al.   PEDIATRIC PULMONOLOGY

Increased Oxidative Stress Induces Apoptosis in Human Cystic Fibrosis Cells

(2011) Mathilde Rottner et al.   PLoS One

Recent trends in cystic fibrosis-related diabetes

(2011) Brandon M Nathan et al.   Current Opinion in Endocrinology Diabetes and Obesity

Effects of Gender and Age at Diagnosis on Disease Progression in Long-term Survivors of Cystic Fibrosis

(2010) Jerry A. Nick et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

The iron chelator, desferrioxamine, reduces inflammation and atherosclerotic lesion development in experimental mice

(2010) Wei-Jian Zhang et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

CFTR Depletion Results in Changes in Fatty Acid Composition and Promotes Lipogenesis in Intestinal Caco 2/15 Cells

(2010) Geneviève Mailhot et al.   PLoS One

Oxidative Stress and Mitochondrial Functions in the Intestinal Caco-2/15 Cell Line

(2010) Rame Taha et al.   PLoS One

Mitochondrial fusion proteins: Dual regulators of morphology and metabolism

(2010) Antonio Zorzano et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Efficacy and Safety of a New Formulation of Pancrelipase (Ultrase MT20) in the Treatment of Malabsorption in Exocrine Pancreatic Insufficiency in Cystic Fibrosis

(2010) Michael W. Konstan et al.   Gastroenterology Research and Practice

CFTR knockdown stimulates lipid synthesis and transport in intestinal Caco-2/15 cells

(2009) Geneviève Mailhot et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Cystic Fibrosis-Related Diabetes: Current Trends in Prevalence, Incidence, and Mortality

(2009) A. Moran et al.   DIABETES CARE

Role of Oxidative Stress in Pancreatic Inflammation

(2008) Po Sing Leung et al.   ANTIOXIDANTS & REDOX SIGNALING

Iron overload following red blood cell transfusion and its impact on disease severity

(2008) Caroline P. Ozment et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Mitochondrial Reactive Oxygen Species Are Obligatory Signals for Glucose-Induced Insulin Secretion

(2008) C. Leloup et al.   DIABETES

Glucolipotoxicity: Fuel Excess and β-Cell Dysfunction

(2008) Vincent Poitout et al.   ENDOCRINE REVIEWS

Oxidative stress and cystic fibrosis-related diabetes: A pilot study in children

(2008) Thierry Ntimbane et al.   Journal of Cystic Fibrosis

Lipid profile, fatty acid composition and pro- and anti-oxidant status in pediatric patients with attention-deficit/hyperactivity disorder

(2008) Schohraya Spahis et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS