Intracellular ascorbate tightens the endothelial permeability barrier through Epac1 and the tubulin cytoskeleton

Intracellular Ascorbate Prevents Endothelial Barrier Permeabilization by Thrombin

(2015) William H. Parker et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ascorbate reverses high glucose- and RAGE-induced leak of the endothelial permeability barrier

(2014) M. Elizabeth Meredith et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

A derivative of ascorbic acid modulates cAMP production

(2013) B. Bordignon et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The leading role of microtubules in endothelial barrier dysfunction: Disassembly of peripheral microtubules leaves behind the cytoskeletal reorganization

(2013) Irina B. Alieva et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

5-Cyano-6-oxo-1,6-dihydro-pyrimidines as potent antagonists targeting exchange proteins directly activated by cAMP

(2012) Haijun Chen et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Cilostazol Strengthens Barrier Integrity in Brain Endothelial Cells

(2012) Shoji Horai et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Epac: Defining a New Mechanism for cAMP Action

(2010) Martijn Gloerich et al.   Annual Review of Pharmacology and Toxicology

Regulation of Endothelial Permeability via Paracellular and Transcellular Transport Pathways

(2010) Yulia Komarova et al.   Annual Review of Physiology

Nitric oxide mediates tightening of the endothelial barrier by ascorbic acid

(2010) James M. May et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Ascorbic acid prevents increased endothelial permeability caused by oxidized low density lipoprotein

(2010) James M. May et al.   FREE RADICAL RESEARCH

Transfer of ascorbic acid across the vascular endothelium: mechanism and self-regulation

(2009) James M. May et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

EPAC proteins transduce diverse cellular actions of cAMP

(2009) Gillian Borland et al.   BRITISH JOURNAL OF PHARMACOLOGY

Advanced glycation end products increase endothelial permeability through the RAGE/Rho signaling pathway

(2009) Akiko Hirose et al.   FEBS LETTERS

Rac GTPase is a hub for protein kinase A and Epac signaling in endothelial barrier protection by cAMP

(2009) Anna A. Birukova et al.   MICROVASCULAR RESEARCH

Regulation of Endothelial Junctional Permeability

(2008) Emily Vandenbroucke et al.   Annals of the New York Academy of Sciences

Role of Epac1, an Exchange Factor for Rap GTPases, in Endothelial Microtubule Dynamics and Barrier Function

(2008) Seema Sehrawat et al.   MOLECULAR BIOLOGY OF THE CELL