Malignant hyperthermia-associated mutations in the S2-S3 cytoplasmic loop of type 1 ryanodine receptor calcium channel impair calcium-dependent inactivation

The EF-hand Ca2+Binding Domain Is Not Required for Cytosolic Ca2+Activation of the Cardiac Ryanodine Receptor

(2015) Wenting Guo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Two Regions of the Ryanodine Receptor Calcium Channel Are Involved in Ca2+-Dependent Inactivation

(2014) Angela C. Gomez et al.   BIOCHEMISTRY

Structure of a mammalian ryanodine receptor

(2014) Ran Zalk et al.   NATURE

Structure of the rabbit ryanodine receptor RyR1 at near-atomic resolution

(2014) Zhen Yan et al.   NATURE

Architecture and conformational switch mechanism of the ryanodine receptor

(2014) Rouslan G. Efremov et al.   NATURE

Pathogenic Mechanisms in Centronuclear Myopathies

(2014) Heinz Jungbluth et al.   Frontiers in Aging Neuroscience

Skeletal Muscle Ryanodine Receptor Mutations Associated with Malignant Hyperthermia Showed Enhanced Intensity and Sensitivity to Triggering Drugs when Expressed in Human Embryonic Kidney Cells

(2013) Keisaku Sato et al.   ANESTHESIOLOGY

Mapping domains and mutations on the skeletal muscle ryanodine receptor channel

(2012) Jean H. Hwang et al.   TRENDS IN MOLECULAR MEDICINE

Mice expressing T4826I-RYR1 are viable but exhibit sex- and genotype-dependent susceptibility to malignant hyperthermia and muscle damage

(2011) Benjamin Yuen et al.   FASEB JOURNAL

Gene Dose Influences Cellular and Calcium Channel Dysregulation in Heterozygous and Homozygous T4826I-RYR1 Malignant Hyperthermia-susceptible Muscle

(2011) Genaro C. Barrientos et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ryanodine receptors

(2011) E Michelle Capes et al.   Skeletal Muscle

Functional Studies of RYR1 Mutations in the Skeletal Muscle Ryanodine Receptor Using Human RYR1 Complementary DNA

(2010) Keisaku Sato et al.   ANESTHESIOLOGY

Identification and Biochemical Characterization of a Novel Ryanodine Receptor Gene Mutation Associated with Malignant Hyperthermia

(2009) Ayuk A. Anderson et al.   ANESTHESIOLOGY

Ryanodine Receptor Structure: Progress and Challenges

(2008) Susan L. Hamilton et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Calcium-dependent Inactivation Terminates Calcium Release in Skeletal Muscle of Amphibians

(2008) Eduardo Ríos et al.   JOURNAL OF GENERAL PHYSIOLOGY