Forced cell cycle exit and modulation of GABAA, CREB, and GSK3β signaling promote functional maturation of induced pluripotent stem cell-derived neurons

HD iPSC-derived neural progenitors accumulate in culture and are susceptible to BDNF withdrawal due to glutamate toxicity

(2015) Virginia B. Mattis et al.   HUMAN MOLECULAR GENETICS

Characterization of bipolar disorder patient-specific induced pluripotent stem cells from a family reveals neurodevelopmental and mRNA expression abnormalities

(2015) J M Madison et al.   MOLECULAR PSYCHIATRY

MECP2e1 isoform mutation affects the form and function of neurons derived from Rett syndrome patient iPS cells

(2015) Ugljesa Djuric et al.   NEUROBIOLOGY OF DISEASE

Neuronal medium that supports basic synaptic functions and activity of human neurons in vitro

(2015) Cedric Bardy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

N-butylidenephthalide Attenuates Alzheimer's Disease-Like Cytopathy in Down Syndrome Induced Pluripotent Stem Cell-Derived Neurons

(2015) Chia-Yu Chang et al.   Scientific Reports

Induced pluripotent stem cell (iPSC)-derived dopaminergic models of Parkinson's disease: Figure 1

(2015) Joel E. Beevers et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

A Comprehensive Library of Familial Human Amyotrophic Lateral Sclerosis Induced Pluripotent Stem Cells

(2015) Ying Li et al.   PLoS One

Generating Human Neurons In Vitro and Using Them to Understand Neuropsychiatric Disease

(2014) Sergiu P. Paşca et al.   Annual Review of Neuroscience

Maturation of AMPAR Composition and the GABAAR Reversal Potential in hPSC-Derived Cortical Neurons

(2014) M. R. Livesey et al.   JOURNAL OF NEUROSCIENCE

Induced Pluripotent Stem Cells for Disease Modeling and Drug Discovery in Neurodegenerative Diseases

(2014) Lei Cao et al.   MOLECULAR NEUROBIOLOGY

Induced Pluripotent Stem Cell (iPSC) Models of Bipolar Disorder

(2014) K Sue O'Shea et al.   NEUROPSYCHOPHARMACOLOGY

Physiological Characterisation of Human iPS-Derived Dopaminergic Neurons

(2014) Elizabeth M. Hartfield et al.   PLoS One

A Time Course Analysis of the Electrophysiological Properties of Neurons Differentiated from Human Induced Pluripotent Stem Cells (iPSCs)

(2014) Deborah Prè et al.   PLoS One

iPSC-Derived Forebrain Neurons from FXS Individuals Show Defects in Initial Neurite Outgrowth

(2014) Matthew E. Doers et al.   STEM CELLS AND DEVELOPMENT

iPS cell technologies: significance and applications to CNS regeneration and disease

(2014) Hideyuki Okano et al.   Molecular Brain

The Autism Spectrum Disorders Stem Cell Resource at Children's Hospital of Orange County: Implications for Disease Modeling and Drug Discovery

(2014) David J. Brick et al.   Stem Cells Translational Medicine

Human iPSC Neurons Display Activity-Dependent Neurotransmitter Secretion: Aberrant Catecholamine Levels in Schizophrenia Neurons

(2014) Vivian Hook et al.   Stem Cell Reports

Functional Maturation of hPSC-Derived Forebrain Interneurons Requires an Extended Timeline and Mimics Human Neural Development

(2013) Cory R. Nicholas et al.   Cell Stem Cell

In vitro neurogenesis: development and functional implications of iPSC technology

(2013) Claudia Compagnucci et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Function and Dysfunction of Presenilin

(2013) Jie Shen   Neurodegenerative Diseases

Stimulation of GABA-Induced Ca2+ Influx Enhances Maturation of Human Induced Pluripotent Stem Cell-Derived Neurons

(2013) David J. Rushton et al.   PLoS One

Multiple roles of Activin/Nodal, bone morphogenetic protein, fibroblast growth factor and Wnt/ -catenin signalling in the anterior neural patterning of adherent human embryonic stem cell cultures

(2013) G. Lupo et al.   Open Biology

Induced Pluripotent Stem Cells from Patients with Huntington's Disease Show CAG-Repeat-Expansion-Associated Phenotypes

(2012) The HD iPSC Consortium   Cell Stem Cell

Probing sporadic and familial Alzheimer’s disease using induced pluripotent stem cells

(2012) Mason A. Israel et al.   NATURE

Human cerebral cortex development from pluripotent stem cells to functional excitatory synapses

(2012) Yichen Shi et al.   NATURE NEUROSCIENCE

Mutant induced pluripotent stem cell lines recapitulate aspects of TDP-43 proteinopathies and reveal cell-specific vulnerability

(2012) B. Bilican et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Loss of Cdk2 and Cdk4 Induces a Switch from Proliferation to Differentiation in Neural Stem Cells

(2012) Shuhui Lim et al.   STEM CELLS

Coordinated Development of Voltage-Gated Na+ and K+ Currents Regulates Functional Maturation of Forebrain Neurons Derived from Human Induced Pluripotent Stem Cells

(2012) Mingke Song et al.   STEM CELLS AND DEVELOPMENT

CREB in adult neurogenesis - master and partner in the development of adult-born neurons?

(2011) Katharina Merz et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Activity-dependent calcium signaling and ERK-MAP kinases in neurons: A link to structural plasticity of the nucleus and gene transcription regulation

(2010) J. Simon Wiegert et al.   CELL CALCIUM

Small molecule BDNF mimetics activate TrkB signaling and prevent neuronal degeneration in rodents

(2010) Stephen M. Massa et al.   JOURNAL OF CLINICAL INVESTIGATION

Inhibition of Notch Signaling in Human Embryonic Stem Cell-Derived Neural Stem Cells Delays G1/S Phase Transition and Accelerates Neuronal Differentiation In Vitro and In Vivo

(2010) Lodovica Borghese et al.   STEM CELLS

Establishment of Axon-Dendrite Polarity in Developing Neurons

(2009) Anthony P. Barnes et al.   Annual Review of Neuroscience

GABA-cAMP Response Element-Binding Protein Signaling Regulates Maturation and Survival of Newly Generated Neurons in the Adult Hippocampus

(2009) R. Jagasia et al.   JOURNAL OF NEUROSCIENCE

NS21: Re-defined and modified supplement B27 for neuronal cultures

(2008) Yucui Chen et al.   JOURNAL OF NEUROSCIENCE METHODS

A cAMP-Dependent, Protein Kinase A-Independent Signaling Pathway Mediating Neuritogenesis through Egr1 in PC12 Cells

(2008) A. Ravni et al.   MOLECULAR PHARMACOLOGY

cAMP promotes neurite outgrowth and extension through protein kinase A but independently of Erk activation in cultured rat motoneurons

(2008) C. Aglah et al.   NEUROPHARMACOLOGY