Recurrent Loss-of-Function Mutations Reveal Costs to OAS1 Antiviral Activity in Primates

Title
Recurrent Loss-of-Function Mutations Reveal Costs to OAS1 Antiviral Activity in Primates
Authors
Keywords
oligoadenylate synthetase 1, OAS1, RNase L, rapid evolution, polymorphism, primates, loss-of-function mutation, yeast, double-stranded RNA, dsRNA
Journal
Cell Host & Microbe
Volume 25, Issue 2, Pages 336-343.e4
Publisher
Elsevier BV
Online
2019-02-01
DOI
10.1016/j.chom.2019.01.001

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