Cardiovascular toxicities associated with immune checkpoint inhibitors

T cell checkpoint regulators in the heart

(2019) Nir Grabie et al.   CARDIOVASCULAR RESEARCH

OUP accepted manuscript

(2018)   CARDIOVASCULAR RESEARCH

Vasculitis associated with immune checkpoint inhibitors—a systematic review

(2018) Anisha Daxini et al.   CLINICAL RHEUMATOLOGY

Management of Immune-Related Adverse Events in Patients Treated With Immune Checkpoint Inhibitor Therapy: American Society of Clinical Oncology Clinical Practice Guideline

(2018) Julie R. Brahmer et al.   JOURNAL OF CLINICAL ONCOLOGY

Cardiac Toxicity in Patients Treated With Immune Checkpoint Inhibitors

(2018) Carlo G. Tocchetti et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Myocarditis in Patients Treated With Immune Checkpoint Inhibitors

(2018) Syed S. Mahmood et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

PD-1 Modulates Radiation-Induced Cardiac Toxicity through Cytotoxic T Lymphocytes

(2018) Shisuo Du et al.   Journal of Thoracic Oncology

Increased reporting of fatal immune checkpoint inhibitor-associated myocarditis

(2018) Javid J Moslehi et al.   LANCET

Cancer immunotherapy efficacy and patients' sex: a systematic review and meta-analysis

(2018) Fabio Conforti et al.   LANCET ONCOLOGY

Preliminary results for avelumab plus axitinib as first-line therapy in patients with advanced clear-cell renal-cell carcinoma (JAVELIN Renal 100): an open-label, dose-finding and dose-expansion, phase 1b trial

(2018) Toni K Choueiri et al.   LANCET ONCOLOGY

Cardiorenal complications of immune checkpoint inhibitors

(2018) Krishna Sury et al.   Nature Reviews Nephrology

Cancer immunotherapy using checkpoint blockade

(2018) Antoni Ribas et al.   SCIENCE

Takotsubo-Like Syndrome in Cancer Patients Treated With Immune Checkpoint Inhibitors

(2018) Stephane Ederhy et al.   JACC-Cardiovascular Imaging

Ipilimumab induced digital vasculitis

(2018) Amrita Padda et al.   Journal for ImmunoTherapy of Cancer

Immune checkpoint inhibitors and cardiovascular toxicity

(2018) Alexander R Lyon et al.   LANCET ONCOLOGY

Fatal Toxic Effects Associated With Immune Checkpoint Inhibitors

(2018) Daniel Y. Wang et al.   JAMA Oncology

Immune Checkpoint Inhibitor Toxicity in 2018

(2018) Douglas B. Johnson et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Cardiovascular toxicities associated with immune checkpoint inhibitors: an observational, retrospective, pharmacovigilance study

(2018) Joe-Elie Salem et al.   LANCET ONCOLOGY

Pharmacovigilating cardiotoxicity of immune checkpoint inhibitors

(2018) Gilda Varricchi et al.   LANCET ONCOLOGY

Prevalence of immune-related systemic adverse events in patients treated with anti-Programmed cell Death 1/anti-Programmed cell Death-Ligand 1 agents: A single-centre pharmacovigilance database analysis

(2017) Sébastien Le Burel et al.   EUROPEAN JOURNAL OF CANCER

New-onset third-degree atrioventricular block because of autoimmune-induced myositis under treatment with anti-programmed cell death-1 (nivolumab) for metastatic melanoma

(2017) Juliane Behling et al.   MELANOMA RESEARCH

Immunoinhibitory checkpoint deficiency in medium and large vessel vasculitis

(2017) Hui Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Acquired IFNγ resistance impairs anti-tumor immunity and gives rise to T-cell-resistant melanoma lesions

(2017) Antje Sucker et al.   Nature Communications

Plasma brain natriuretic peptide levels are elevated in patients with cancer

(2017) Sachiko Bando et al.   PLoS One

Left Ventricular Dysfunction After Treatment With Ipilimumab for Metastatic Melanoma

(2016) Mary E. Roth et al.   AMERICAN JOURNAL OF THERAPEUTICS

Cancer immunotherapy: the beginning of the end of cancer?

(2016) Sofia Farkona et al.   BMC Medicine

Nivolumab-Induced Pericardial Tamponade: A Case Report and Discussion

(2016) Igal Kushnir et al.   CARDIOLOGY

Pericardial effusion with tamponade physiology induced by nivolumab

(2016) Jennifer Nesfeder et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Apical takotsubo syndrome in a patient with metastatic breast carcinoma on novel immunotherapy

(2016) Robert D. Anderson et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Polymyalgia Rheumatica and Giant Cell Arteritis

(2016) Frank Buttgereit et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Fulminant Myocarditis with Combination Immune Checkpoint Blockade

(2016) Douglas B. Johnson et al.   NEW ENGLAND JOURNAL OF MEDICINE

Induction of autoimmune disease by deletion of CTLA-4 in mice in adulthood

(2016) Katrin Klocke et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rapid granulomatosis with polyangiitis induced by immune checkpoint inhibition

(2016) Rob R. H. van den Brom et al.   RHEUMATOLOGY

Intestinal microbiome analyses identify melanoma patients at risk for checkpoint-blockade-induced colitis

(2016) Krista Dubin et al.   Nature Communications

Primary Resistance to PD-1 Blockade Mediated by JAK1/2 Mutations

(2016) Daniel Sanghoon Shin et al.   Cancer Discovery

Treatment of the Immune-Related Adverse Effects of Immune Checkpoint Inhibitors

(2016) Claire F. Friedman et al.   JAMA Oncology

Cardiotoxicity associated with CTLA4 and PD1 blocking immunotherapy

(2016) Lucie Heinzerling et al.   Journal for ImmunoTherapy of Cancer

Cardiac troponin testing in idiopathic inflammatory myopathies and systemic sclerosis-spectrum disorders: biomarkers to distinguish between primary cardiac involvement and low-grade skeletal muscle disease activity

(2015) Michael Hughes et al.   ANNALS OF THE RHEUMATIC DISEASES

2015 ESC Guidelines for the diagnosis and management of pericardial diseases

(2015) Yehuda Adler et al.   EUROPEAN HEART JOURNAL

Combined Nivolumab and Ipilimumab or Monotherapy in Untreated Melanoma

(2015) James Larkin et al.   NEW ENGLAND JOURNAL OF MEDICINE

Acute heart failure due to autoimmune myocarditis under pembrolizumab treatment for metastatic melanoma

(2015) Heinz Läubli et al.   Journal for ImmunoTherapy of Cancer

Apical ballooning and cardiomyopathy in a melanoma patient treated with ipilimumab: a case of takotsubo-like syndrome

(2015) Benjamin P Geisler et al.   Journal for ImmunoTherapy of Cancer

Upregulation of Programmed Death-1 and Its Ligand in Cardiac Injury Models: Interaction with GADD153

(2015) Babak Baban et al.   PLoS One

VISTA Is an Immune Checkpoint Molecule for Human T Cells

(2014) J. L. Lines et al.   CANCER RESEARCH

The immune checkpoint inhibitors: where are we now?

(2014) Rachel M. Webster   NATURE REVIEWS DRUG DISCOVERY

Retinal vasculitis and ocular vitreous metastasis following complete response to PD-1 inhibition in a patient with metastatic cutaneous melanoma

(2014) Joshua S Manusow et al.   Journal for ImmunoTherapy of Cancer

Current state of knowledge on aetiology, diagnosis, management, and therapy of myocarditis: a position statement of the European Society of Cardiology Working Group on Myocardial and Pericardial Diseases

(2013) A. L. P. Caforio et al.   EUROPEAN HEART JOURNAL

Tim-3 Expression Defines Regulatory T Cells in Human Tumors

(2013) Jing Yan et al.   PLoS One

Drug-Associated Polymyalgia Rheumatica/Giant Cell Arteritis Occurring in Two Patients After Treatment With Ipilimumab, an Antagonist of CTLA-4

(2013) Barbara L. Goldstein et al.   Arthritis & Rheumatology

Update on Myocarditis

(2012) Ingrid Kindermann et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Colocalization of Inflammatory Response with B7-H1 Expression in Human Melanocytic Lesions Supports an Adaptive Resistance Mechanism of Immune Escape

(2012) J. M. Taube et al.   Science Translational Medicine

PD-1 deficiency results in the development of fatal myocarditis in MRL mice

(2010) Jian Wang et al.   INTERNATIONAL IMMUNOLOGY

BSR and BHPR guidelines for the management of giant cell arteritis

(2010) B. Dasgupta et al.   RHEUMATOLOGY

Cardiovascular Magnetic Resonance in Myocarditis: A JACC White Paper

(2009) Matthias G. Friedrich et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

The surface protein TIGIT suppresses T cell activation by promoting the generation of mature immunoregulatory dendritic cells

(2008) Xin Yu et al.   NATURE IMMUNOLOGY