MyD88-dependent signaling in non-parenchymal cells promotes liver carcinogenesis

The immunology of hepatocellular carcinoma

(2018) Marc Ringelhan et al.   NATURE IMMUNOLOGY

The contribution of toll-like receptor signaling to the development of liver fibrosis and cancer in hepatocyte-specific TAK1-deleted mice

(2017) Isabelle Jingyi Song et al.   INTERNATIONAL JOURNAL OF CANCER

Hepatocellular carcinoma

(2016) Josep M. Llovet et al.   Nature Reviews Disease Primers

Kupffer Cells Undergo Fundamental Changes during the Development of Experimental NASH and Are Critical in Initiating Liver Damage and Inflammation

(2016) D. T. Reid et al.   PLoS One

Lack of gp130 expression in hepatocytes attenuates tumor progression in the DEN model

(2015) M Hatting et al.   Cell Death & Disease

Cancer incidence and mortality worldwide: Sources, methods and major patterns in GLOBOCAN 2012

(2014) Jacques Ferlay et al.   INTERNATIONAL JOURNAL OF CANCER

Toll-like receptor 4 activity protects against hepatocellular tumorigenesis and progression by regulating expression of DNA repair protein Ku70 in mice

(2013) Ziyan Wang et al.   HEPATOLOGY

Toll-like receptors in alcoholic liver disease, non-alcoholic steatohepatitis and carcinogenesis

(2013) Yoon Seok Roh et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Antioxidant N-Acetylcysteine Attenuates Hepatocarcinogenesis by Inhibiting ROS/ER Stress in TLR2 Deficient Mouse

(2013) Heng Lin et al.   PLoS One

MyD88 and its divergent toll in carcinogenesis

(2013) Rosalba Salcedo et al.   TRENDS IN IMMUNOLOGY

Promotion of Hepatocellular Carcinoma by the Intestinal Microbiota and TLR4

(2012) Dianne H. Dapito et al.   CANCER CELL

Experimental and natural infections in MyD88- and IRAK-4-deficient mice and humans

(2012) Horst von Bernuth et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Sterile Inflammation in the Liver

(2012) Paul Kubes et al.   GASTROENTEROLOGY

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Pharmacological inhibition of the chemokine CCL2 (MCP-1) diminishes liver macrophage infiltration and steatohepatitis in chronic hepatic injury

(2011) Christer Baeck et al.   GUT

Role of innate immunity and the microbiota in liver fibrosis: crosstalk between the liver and gut

(2011) Ekihiro Seki et al.   JOURNAL OF PHYSIOLOGY-LONDON

MyD88-dependent pathway accelerates the liver damage of Concanavalin A-induced hepatitis

(2010) Keisuke Ojiro et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Toll-Like Receptor 9 Promotes Steatohepatitis by Induction of Interleukin-1β in Mice

(2010) Kouichi Miura et al.   GASTROENTEROLOGY

Endotoxin accumulation prevents carcinogen-induced apoptosis and promotes liver tumorigenesis in rodents

(2010) Le-Xing Yu et al.   HEPATOLOGY

MyD88 Deficiency Leads to Decreased NK Cell Gamma Interferon Production and T Cell Recruitment duringChlamydia muridarumGenital Tract Infection, but a Predominant Th1 Response and Enhanced Monocytic Inflammation Are Associated with Infection Resolution

(2010) Uma M. Nagarajan et al.   INFECTION AND IMMUNITY

Proliferative and Nonproliferative Lesions of the Rat and Mouse Hepatobiliary System

(2010) Bob Thoolen et al.   TOXICOLOGIC PATHOLOGY

Current Views of Toll-Like Receptor Signaling Pathways

(2010) Masahiro Yamamoto et al.   Gastroenterology Research and Practice

Hepatocyte-specific NEMO deletion promotes NK/NKT cell– and TRAIL-dependent liver damage

(2009) Naiara Beraza et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Toll-like Receptors Activate Innate and Adaptive Immunity by using Dendritic Cell-Intrinsic and -Extrinsic Mechanisms

(2008) Baidong Hou et al.   IMMUNITY

Demonstration of inflammation-induced cancer and cancer immunoediting during primary tumorigenesis

(2008) J. B. Swann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA