The garlic compound ajoene covalently binds vimentin, disrupts the vimentin network and exerts anti-metastatic activity in cancer cells

Vimentin Diversity in Health and Disease

(2018) Frida Danielsson et al.   Cells

Vimentin Modulates Infectious Internalization of Human Papillomavirus 16 Pseudovirions

(2017) Georgia Schäfer et al.   JOURNAL OF VIROLOGY

Diallyl trisulfides, a natural histone deacetylase inhibitor, attenuate HIF-1α synthesis, and decreases breast cancer metastasis

(2017) Zhonghong Wei et al.   MOLECULAR CARCINOGENESIS

The Cytotoxicity of the Ajoene Analogue BisPMB in WHCO1 Oesophageal Cancer Cells Is Mediated by CHOP/GADD153

(2017) Vuyolwethu Siyo et al.   MOLECULES

The cytotoxicity of garlic-related disulphides and thiosulfonates in WHCO1 oesophageal cancer cells is dependent on S-thiolation and not production of ROS

(2016) Muneerah Smith et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Garlic and Onions: Their Cancer Prevention Properties

(2015) H. L. Nicastro et al.   Cancer Prevention Research

The basics of thiols and cysteines in redox biology and chemistry

(2015) Leslie B. Poole   FREE RADICAL BIOLOGY AND MEDICINE

The garlic compound ajoene targets protein folding in the endoplasmic reticulum of cancer cells

(2015) Catherine H. Kaschula et al.   MOLECULAR CARCINOGENESIS

Diallyl disulfide inhibits growth and metastatic potential of human triple-negative breast cancer cells through inactivation of the β-catenin signaling pathway

(2015) Jing Huang et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Glutathione-Garlic Sulfur Conjugates: Slow Hydrogen Sulfide Releasing Agents for Therapeutic Applications

(2015) Ashif Bhuiyan et al.   MOLECULES

Vimentin filament organization and stress sensing depend on its single cysteine residue and zinc binding

(2015) Dolores Pérez-Sala et al.   Nature Communications

The Immunomodulation and Anti-Inflammatory Effects of Garlic Organosulfur Compounds in Cancer Chemoprevention

(2014) Georgia Schäfer et al.   Anti-Cancer Agents in Medicinal Chemistry

Diallyl Disulfide Suppresses SRC/Ras/ERK Signaling-Mediated Proliferation and Metastasis in Human Breast Cancer by Up-Regulating miR-34a

(2014) Xiangsheng Xiao et al.   PLoS One

Epithelial to mesenchymal transition inducing transcription factors and metastatic cancer

(2014) Mousumi Tania et al.   TUMOR BIOLOGY

Jaguar: A high-performance quantum chemistry software program with strengths in life and materials sciences

(2013) Art D. Bochevarov et al.   INTERNATIONAL JOURNAL OF QUANTUM CHEMISTRY

Protein and ligand preparation: parameters, protocols, and influence on virtual screening enrichments

(2013) G. Madhavi Sastry et al.   JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN

Anti-Proliferative Activity of Synthetic Ajoene Analogues on Cancer Cell-Lines

(2012) Catherine H. Kaschula et al.   Anti-Cancer Agents in Medicinal Chemistry

Structure–activity studies on the anti-proliferation activity of ajoene analogues in WHCO1 oesophageal cancer cells

(2012) Catherine H. Kaschula et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Analysis of the nuclear proteome of the resurrection plant Xerophyta viscosa in response to dehydration stress using iTRAQ with 2DLC and tandem mass spectrometry

(2012) Kamal Omer Abdalla et al.   Journal of Proteomics

A Garlic Derivative, S-allylcysteine (SAC), Suppresses Proliferation and Metastasis of Hepatocellular Carcinoma

(2012) Kevin T. P. Ng et al.   PLoS One

S-allylmercaptocysteine effectively inhibits the proliferation of colorectal cancer cells under in vitro and in vivo conditions

(2011) Desen Liang et al.   CANCER LETTERS

Vimentin in cancer and its potential as a molecular target for cancer therapy

(2011) Arun Satelli et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Reversible and irreversible protein glutathionylation: biological and clinical aspects

(2011) Arthur JL Cooper et al.   Expert Opinion on Drug Metabolism & Toxicology

Oxidative species and S-glutathionyl conjugates in the apoptosis induction by allyl thiosulfate

(2011) Ridvan Nepravishta et al.   FEBS Journal

Protein S-glutathiolation: Redox-sensitive regulation of protein function

(2011) Bradford G. Hill et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Vimentin induces changes in cell shape, motility, and adhesion during the epithelial to mesenchymal transition

(2010) Melissa G. Mendez et al.   FASEB JOURNAL

S-Glutathiolation in life and death decisions of the cell

(2010) Isabella Dalle-Donne et al.   FREE RADICAL RESEARCH

Plasticity of Intermediate Filament Subunits

(2010) Robert Kirmse et al.   PLoS One

Orchestrating Redox Signaling Networks through Regulatory Cysteine Switches

(2009) Candice E. Paulsen et al.   ACS Chemical Biology

Intermediate filaments exchange subunits along their length and elongate by end-to-end annealing

(2009) Gülsen Çolakoğlu et al.   JOURNAL OF CELL BIOLOGY

Protein S-glutathionylation: a regulatory device from bacteria to humans

(2009) Isabella Dalle-Donne et al.   TRENDS IN BIOCHEMICAL SCIENCES

Rhodanese-thioredoxin system and allyl sulfur compounds

(2008) Renato Sabelli et al.   FEBS Journal

Conformational Preferences and pKaValue of Cysteine Residue

(2008) Joo Yun Lee et al.   JOURNAL OF PHYSICAL CHEMISTRY B