Circadian oscillator proteins across the kingdoms of life: structural aspects

CRY1 interacts directly with HBI1 to regulate its transcriptional activity and photomorphogenesis in Arabidopsis

(2018) Sheng Wang et al.   JOURNAL OF EXPERIMENTAL BOTANY

Conformational rearrangements of the C1 ring in KaiC measure the timing of assembly with KaiB

(2018) Atsushi Mukaiyama et al.   Scientific Reports

Structures of the cyanobacterial circadian oscillator frozen in a fully assembled state

(2017) Joost Snijder et al.   SCIENCE

Structural basis of the day-night transition in a bacterial circadian clock

(2017) Roger Tseng et al.   SCIENCE

The CNT1 Domain of Arabidopsis CRY1 Alone Is Sufficient to Mediate Blue Light Inhibition of Hypocotyl Elongation

(2015) Sheng-Bo He et al.   Molecular Plant

Atomic-scale origins of slowness in the cyanobacterial circadian clock

(2015) J. Abe et al.   SCIENCE

A protein fold switch joins the circadian oscillator to clock output in cyanobacteria

(2015) Y.-G. Chang et al.   SCIENCE

Exchange of ADP with ATP in the CII ATPase domain promotes autophosphorylation of cyanobacterial clock protein KaiC

(2014) T. Nishiwaki-Ohkawa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An electromagnetic field disrupts negative geotaxis in Drosophila via a CRY-dependent pathway

(2014) Giorgio Fedele et al.   Nature Communications

Cell Type-Specific Functions of Period Genes Revealed by Novel Adipocyte and Hepatocyte Circadian Clock Models

(2014) Chidambaram Ramanathan et al.   PLoS Genetics

Genetic Analysis of Circadian Responses to Low Frequency Electromagnetic Fields in Drosophila melanogaster

(2014) Giorgio Fedele et al.   PLoS Genetics

Structures of Drosophila Cryptochrome and Mouse Cryptochrome1 Provide Insight into Circadian Function

(2013) Anna Czarna et al.   CELL

Crystal structure of mammalian cryptochrome in complex with a small molecule competitor of its ubiquitin ligase

(2013) Shannon Nangle et al.   CELL RESEARCH

Cooperative KaiA–KaiB–KaiC Interactions Affect KaiB/SasA Competition in the Circadian Clock of Cyanobacteria

(2013) Roger Tseng et al.   JOURNAL OF MOLECULAR BIOLOGY

Two Antagonistic Clock-Regulated Histidine Kinases Time the Activation of Circadian Gene Expression

(2013) Andrian Gutu et al.   MOLECULAR CELL

SCFFBXL3 ubiquitin ligase targets cryptochromes at their cofactor pocket

(2013) Weiman Xing et al.   NATURE

Updated structure of Drosophila cryptochrome

(2013) Colin Levy et al.   NATURE

Robust and tunable circadian rhythms from differentially sensitive catalytic domains

(2013) C. Phong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of Per1 and the mineralocorticoid receptor in the coordinate regulation of αENaC in renal cortical collecting duct cells

(2013) Jacob Richards et al.   Frontiers in Physiology

Dephosphorylation of the Core Clock Protein KaiC in the Cyanobacterial KaiABC Circadian Oscillator Proceeds via an ATP Synthase Mechanism

(2012) Martin Egli et al.   BIOCHEMISTRY

LOV Domain-Containing F-Box Proteins: Light-Dependent Protein Degradation Modules in Arabidopsis

(2012) Shogo Ito et al.   Molecular Plant

Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists

(2012) Laura A. Solt et al.   NATURE

Regulation of circadian behaviour and metabolism by REV-ERB-α and REV-ERB-β

(2012) Han Cho et al.   NATURE

Peroxiredoxins are conserved markers of circadian rhythms

(2012) Rachel S. Edgar et al.   NATURE

A Triple Helix-Loop-Helix/Basic Helix-Loop-Helix Cascade Controls Cell Elongation Downstream of Multiple Hormonal and Environmental Signaling Pathways in Arabidopsis

(2012) M.-Y. Bai et al.   PLANT CELL

A Triantagonistic Basic Helix-Loop-Helix System Regulates Cell Elongation in Arabidopsis

(2012) M. Ikeda et al.   PLANT CELL

EARLY FLOWERING4 Recruitment of EARLY FLOWERING3 in the Nucleus Sustains the Arabidopsis Circadian Clock

(2012) E. Herrero et al.   PLANT CELL

Arabidopsis circadian clock protein, TOC1, is a DNA-binding transcription factor

(2012) J. M. Gendron et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Unwinding the differences of the mammalian PERIOD clock proteins from crystal structure to cellular function

(2012) N. Kucera et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of Small Molecule Activators of Cryptochrome

(2012) T. Hirota et al.   SCIENCE

Crystal Structure of the Heterodimeric CLOCK:BMAL1 Transcriptional Activator Complex

(2012) N. Huang et al.   SCIENCE

Altered sleep and behavioral activity phenotypes in PER3-deficient mice

(2011) Sibah Hasan et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

The Cyanobacterial Circadian System: From Biophysics to Bioevolution

(2011) Carl Hirschie Johnson et al.   Annual Review of Biophysics

The Cryptochromes: Blue Light Photoreceptors in Plants and Animals

(2011) Inês Chaves et al.   Annual Review of Plant Biology

LUX ARRHYTHMO Encodes a Nighttime Repressor of Circadian Gene Expression in the Arabidopsis Core Clock

(2011) Anne Helfer et al.   CURRENT BIOLOGY

Temporal Repression of Core Circadian Genes Is Mediated through EARLY FLOWERING 3 in Arabidopsis

(2011) Laura E. Dixon et al.   CURRENT BIOLOGY

Light input and processing in the circadian clock of Neurospora

(2011) Tobias Schafmeier et al.   FEBS LETTERS

Quantitative Analyses of Cryptochrome-mBMAL1 Interactions

(2011) Anna Czarna et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Circadian Rhythm Gene Period 3 Is an Inhibitor of the Adipocyte Cell Fate

(2011) Maria Jose Costa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of the Activity and Cellular Localization of the Circadian Clock Protein FRQ

(2011) Joonseok Cha et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cryptochromes mediate rhythmic repression of the glucocorticoid receptor

(2011) Katja A. Lamia et al.   NATURE

The ELF4–ELF3–LUX complex links the circadian clock to diurnal control of hypocotyl growth

(2011) Dmitri A. Nusinow et al.   NATURE

Structure of full-length Drosophila cryptochrome

(2011) Brian D. Zoltowski et al.   NATURE

A Reduced-Function Allele Reveals ThatEARLY FLOWERING3Repressive Action on the Circadian Clock Is Modulated by Phytochrome Signals inArabidopsis

(2011) Elsebeth Kolmos et al.   PLANT CELL

Flexibility of the C-terminal, or CII, ring of KaiC governs the rhythm of the circadian clock of cyanobacteria

(2011) Y.-G. Chang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genome-Wide and Phase-Specific DNA-Binding Rhythms of BMAL1 Control Circadian Output Functions in Mouse Liver

(2011) Guillaume Rey et al.   PLOS BIOLOGY

Phytochrome three-dimensional structures and functions

(2010) Jon Hughes   BIOCHEMICAL SOCIETY TRANSACTIONS

Kinetics of Conformational Changes of the FKF1-LOV Domain upon Photoexcitation

(2010) Yusuke Nakasone et al.   BIOPHYSICAL JOURNAL

Photoadaptation in Neurospora by Competitive Interaction of Activating and Inhibitory LOV Domains

(2010) Erik Malzahn et al.   CELL

Phytochrome: structural basis for its functions

(2010) Akira Nagatani   CURRENT OPINION IN PLANT BIOLOGY

PRR5 regulates phosphorylation, nuclear import and subnuclear localization of TOC1 in the Arabidopsis circadian clock

(2010) Lei Wang et al.   EMBO JOURNAL

Tracking and visualizing the circadian ticking of the cyanobacterial clock protein KaiC in solution

(2010) Yoriko Murayama et al.   EMBO JOURNAL

The mammalian clock component PERIOD2 coordinates circadian output by interaction with nuclear receptors

(2010) I. Schmutz et al.   GENES & DEVELOPMENT

Cryptochrome mediates circadian regulation of cAMP signaling and hepatic gluconeogenesis

(2010) Eric E Zhang et al.   NATURE MEDICINE

Structure of Rev-erbα bound to N-CoR reveals a unique mechanism of nuclear receptor–co-repressor interaction

(2010) Caroline A Phelan et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Physiology of Circadian Entrainment

(2010) Diego A. Golombek et al.   PHYSIOLOGICAL REVIEWS

Ambient temperature response establishes ELF3 as a required component of the core Arabidopsis circadian clock

(2010) B. Thines et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The KaiA protein of the cyanobacterial circadian oscillator is modulated by a redox-active cofactor

(2010) T. L. Wood et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Physical interaction between VIVID and white collar complex regulates photoadaptation in Neurospora

(2010) C.-H. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular mechanism of the Neurospora circadian oscillator

(2010) Jinhu Guo et al.   Protein & Cell

The Circadian System in Higher Plants

(2009) Stacey L. Harmer   Annual Review of Plant Biology

Serine/Threonine Phosphatases: Mechanism through Structure

(2009) Yigong Shi   CELL

Integrating ELF4 into the circadian system through combined structural and functional studies

(2009) Elsebeth Kolmos et al.   HFSP Journal

Sequential and Compartment-specific Phosphorylation Controls the Life Cycle of the Circadian CLOCK Protein

(2009) Hsiu-Cheng Hung et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Generation of a Novel Allelic Series of Cryptochrome Mutants via Mutagenesis Reveals Residues Involved in Protein-Protein Interaction and CRY2-Specific Repression

(2009) E. V. McCarthy et al.   MOLECULAR AND CELLULAR BIOLOGY

Mechanism-based tuning of a LOV domain photoreceptor

(2009) Brian D Zoltowski et al.   Nature Chemical Biology

CIRCADIAN CLOCK ASSOCIATED1 and LATE ELONGATED HYPOCOTYL Function Synergistically in the Circadian Clock of Arabidopsis

(2009) S. X. Lu et al.   PLANT PHYSIOLOGY

Posttranslational Regulation of CIRCADIAN CLOCK ASSOCIATED1 in the Circadian Oscillator of Arabidopsis

(2009) E. Yakir et al.   PLANT PHYSIOLOGY

Intramolecular Regulation of Phosphorylation Status of the Circadian Clock Protein KaiC

(2009) Yao Xu et al.   PLoS One

Structures of KaiC Circadian Clock Mutant Proteins: A New Phosphorylation Site at T426 and Mechanisms of Kinase, ATPase and Phosphatase

(2009) Rekha Pattanayek et al.   PLoS One

Functional motifs in the (6-4) photolyase crystal structure make a comparative framework for DNA repair photolyases and clock cryptochromes

(2009) K. Hitomi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

AMPK Regulates the Circadian Clock by Cryptochrome Phosphorylation and Degradation

(2009) K. A. Lamia et al.   SCIENCE

A Role for the PERIOD:PERIOD Homodimer in the Drosophila Circadian Clock

(2009) Johannes Landskron et al.   PLOS BIOLOGY

Cryptochrome Mediates Light-Dependent Magnetosensitivity of Drosophila's Circadian Clock

(2009) Taishi Yoshii et al.   PLOS BIOLOGY

Structural and Functional Analyses of PAS Domain Interactions of the Clock Proteins Drosophila PERIOD and Mouse PERIOD2

(2009) Sven Hennig et al.   PLOS BIOLOGY

The Structural Basis of Gas-Responsive Transcription by the Human Nuclear Hormone Receptor REV-ERBβ

(2009) Keith I Pardee et al.   PLOS BIOLOGY

Light Activation of the LOV Protein Vivid Generates a Rapidly Exchanging Dimer†‡

(2008) Brian D. Zoltowski et al.   BIOCHEMISTRY

Higher plants use LOV to perceive blue light

(2008) Emilie Demarsy et al.   CURRENT OPINION IN PLANT BIOLOGY

The nuclear receptors Rev-erbs and RORs integrate circadian rhythms and metabolism

(2008) Hélène Duez et al.   Diabetes & Vascular Disease Research

Dual KaiC-based oscillations constitute the circadian system of cyanobacteria

(2008) Y. Kitayama et al.   GENES & DEVELOPMENT

Post-translational Regulation of theArabidopsisCircadian Clock through Selective Proteolysis and Phosphorylation of Pseudo-response Regulator Proteins

(2008) Sumire Fujiwara et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Interlocked feedback loops of the circadian clock of Neurospora crassa

(2008) Michael Brunner et al.   MOLECULAR MICROBIOLOGY

The genetics of mammalian circadian order and disorder: implications for physiology and disease

(2008) Joseph S. Takahashi et al.   NATURE REVIEWS GENETICS

PBEQ-Solver for online visualization of electrostatic potential of biomolecules

(2008) Sunhwan Jo et al.   NUCLEIC ACIDS RESEARCH

Cyanobacteriochromes: a new superfamily of tetrapyrrole-binding photoreceptors in cyanobacteria

(2008) Masahiko Ikeuchi et al.   PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES

Interactions between circadian and hormonal signalling in plants

(2008) Fiona C. Robertson et al.   PLANT MOLECULAR BIOLOGY

Network Discovery Pipeline Elucidates Conserved Time-of-Day–Specific cis-Regulatory Modules

(2008) Todd P. Michael et al.   PLoS Genetics

The structure of a complete phytochrome sensory module in the Pr ground state

(2008) L.-O. Essen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Crystal structure of Pseudomonas aeruginosa bacteriophytochrome: Photoconversion and signal transduction

(2008) X. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The day/night switch in KaiC, a central oscillator component of the circadian clock of cyanobacteria

(2008) Y.-I. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural Insights into a Circadian Oscillator

(2008) C. H. Johnson et al.   SCIENCE

BIOCHEMISTRY: Metamorphic Proteins

(2008) A. G. Murzin   SCIENCE

Photoexcited CRY2 Interacts with CIB1 to Regulate Transcription and Floral Initiation in Arabidopsis

(2008) H. Liu et al.   SCIENCE

Human and Drosophila Cryptochromes Are Light Activated by Flavin Photoreduction in Living Cells

(2008) Nathalie Hoang et al.   PLOS BIOLOGY

Redundant Function of REV-ERBα and β and Non-Essential Role for Bmal1 Cycling in Transcriptional Regulation of Intracellular Circadian Rhythms

(2008) Andrew C. Liu et al.   PLoS Genetics