Journal
BIOTECHNOLOGY AND BIOENGINEERING
Volume 116, Issue 7, Pages 1594-1603Publisher
WILEY
DOI: 10.1002/bit.26966
Keywords
Bacillus sp; SJ-10; macroalgae; marine renewable resource; poly gamma-d-glutamic acid; Ulva sp
Categories
Funding
- Korea Institute of Marine Science & Technology promotion [20140418]
- Korea Institute of Marine Science & Technology Promotion (KIMST) [201404182] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
- National Research Foundation of Korea [21A20130012185] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
Ask authors/readers for more resources
Numerous studies on poly gamma-d-glutamicacid (gamma-PGA) production have investigated terrestrial renewable sources for reducing production costs, but there are no studies using waste marine resources so far. We aimed to develop a cost-effective production method of gamma-d-PGA by Bacillus sp. SJ-10 using green macroalgae (Ulva sp.) as a major substrate without hydrolysis pretreatment. The SJ-10 was shown to not only cause immediate tissue degradation of the Ulva membrane but also grew well as a sole substrate. The gamma-d-PGA yield was 6.29 +/- 0.34 g/L under optimized conditions via the response surface method, and the produced gamma-d-PGA had a thermal decomposition temperature of 310 degrees C and molecular weight of 250-1780 kDa. The calculated cost efficiency for the final yield was 32% when compared with complex media. Therefore, the present study provided a strategy for promoting an ecofriendly and cost-effective means to produce gamma-d-PGA via a marine renewable resource.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available