Article
Chemistry, Applied
Abdul Hadi Mahmud, Nurul Mahira Salahuddin, Abdul Mutalib Md Jani, Noor Fitrah Abu Bakar, Siti Aimi Sarah Zainal Abidin, Zainiharyati Mohd Zain, Kim-Fatt Low
Summary: A voltammetric immunosensor was developed for detecting porcine serum albumin (PSA) in raw meat products adulterated with pork. The study utilized nanoporous alumina (NPA) millirods as the biorecognition platform, which were covalently bioconjugated with anti-PSA antibodies. The PSA was then tagged with gold nanoparticles as the signaling probe and quantified using voltammetric analysis. The immunosensor showed high specificity and sensitivity, with a limit of detection of 50 pg/mL. Real-world applicability was successfully validated using pork/beef adulterated mixtures with a limit of detection of 0.05% (w/w).
Article
Nanoscience & Nanotechnology
Sivaranjani Devarakonda, Baskar Ganapathysubramanian, Pranav Shrotriya
Summary: The study presents an experimental and computational approach for developing a highly sensitive and responsive label-free biosensor based on aptamer-functionalized transparent electrode. The sensor shows sensitive and specific thrombin protein detection with a high signal-to-noise ratio. Computational and experimental results indicate that the sensing response is due to modified ionic transport under the combined influence of steric hindrance and surface charge modification.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Electrochemistry
Sivaranjani Devarakonda, Sungu Kim, Baskar Ganapathysubramanian, Pranav Shrotriya
Summary: Monitoring electrochemical impedance changes in functionalized nanochannels can be used for chemical and biological sensors. By modeling ionic current and predicting impedance changes, sensor performance can be evaluated and portable diagnostic devices can be designed.
ELECTROCHIMICA ACTA
(2022)
Article
Biochemistry & Molecular Biology
Pornsuda Maraming, Nang Noon Shean Aye, Patcharee Boonsiri, Sakda Daduang, Onanong Buhome, Jureerut Daduang
Summary: Polydopamine nanoparticles (PDA-NPs)-functionalized electrochemical aptasensor was developed for the rapid, sensitive, and cost-effective detection of glycated albumin (GA). The aptasensor showed a broad linearity for GA detection in a clinically relevant range, with low detection limit, good reproducibility, and practicality. Furthermore, the aptasensor demonstrated high selectivity towards GA and potential clinical application in serum samples.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Chemistry, Multidisciplinary
Man Zhu, Fan Xu, Siyuan Miao, Chongyu Xie, Hui Li, Shaoguang Li, Fan Xia
Summary: This study reports the design of an E-AB biosensor with dual recognition sites for rapid detection of thrombin. The biosensor showed faster response time and good performance in terms of dynamic range and specificity.
Article
Nanoscience & Nanotechnology
Kamila Malecka, Elena E. Ferapontova
Summary: Thrombin is a central biomarker in cardiovascular diseases and Alzheimer's disease development, but its electroanalysis is complicated by low physiological concentrations and nonspecific binding. A new electrochemical method was developed to detect femtomolar levels of thrombin in serum and CSF using G4-hemin DNAzyme, which is simple, sensitive, and selective, providing a new tool for ultrasensitive electrocatalytic assays.
ACS APPLIED MATERIALS & INTERFACES
(2021)
Article
Biochemistry & Molecular Biology
Romualdo Troisi, Nicole Balasco, Andreas Santamaria, Luigi Vitagliano, Filomena Sica
Summary: This study investigates the simultaneous binding of two aptamers, NU172 and HD22, to human alpha-thrombin using a structural and dynamics approach. The crystal structure of the ternary complex formed by thrombin with NU172 and HD22_27mer provides insights into the cooperative binding at the two exosites and inspires the design of novel bivalent thrombin inhibitors. The study demonstrates a clear evidence of the synergic action of the two aptamers, with the binding of one aptamer influencing the flexibility and conformation of the other exosite.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Chemistry, Analytical
Yahui Wang, Hongfang Zhang
Summary: Exosome is a potential biomarker for tumor diagnosis. An electrochemical aptasensor for exosome detection was developed using a sandwich-structured nanoporous membrane. The specific probes on one side of the membrane captured the tumor-derived exosomes, while the other side allowed for electrochemical detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2023)
Article
Nanoscience & Nanotechnology
Yanna Lin, Yulong Xu, Yanzhi Xing, Nazhen Liu, Xuwei Chen
Summary: The 3DOM SiO2@ZIF-8-TBA composite, with its ordered macroporous structure, demonstrates high selectivity and superior adsorption capacity towards thrombin. Recovering the retained thrombin with 1.0% NH3·H2O shows a recovery efficiency of 92.3%. The composite-based adsorption/desorption processes have no impact on the conformation of thrombin, as confirmed by circular dichroism spectra.
ACS APPLIED NANO MATERIALS
(2021)
Article
Biochemistry & Molecular Biology
Min-Cheol Lim, Eun Seob Lim, Jeong-A Lim, Sung-Wook Choi, Hyun-Joo Chang
Summary: Aptamer-based methods are more efficient in detecting pesticides due to their high thermal stability, low molecular weight, easy modification, and low cost. In this study, the SELEX process combined with NGS was used to select aptamers specific to the pesticide diazinon. The frequency of specific nucleotide sequences obtained after SELEX rounds was directly analyzed using NGS, eliminating the need for time-consuming cloning process. The selected aptamers showed high binding affinity to diazinon and demonstrated potential for further applications.
APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY
(2022)
Article
Chemistry, Analytical
Hongyuan Cui, Xueqi Fu, Lin Yang, Shu Xing, Xiao-Feng Wang
Summary: The fluorescence resonance energy transfer (FRET) aptasensor constructed with two-dimensional titanium carbides (MXenes) shows high sensitivity and specificity for quantitative detection of thrombin, with a detection limit of 5.27 pM. Among three different aptamers, HD22 exhibits the most sensitivity in detecting thrombin in human plasma, and the Ti3C2 MXene-based sensor can accurately detect thrombin in human serum. These results indicate a great potential of Ti3C2 MXene-based FRET aptasensor in clinical diagnosis.
Article
Chemistry, Analytical
Hui Ma, Shaoqing Lu, Qinghua Xie, Tao Wang, Haifeng Lu, Li Yu
Summary: A liquid crystals sensing platform was demonstrated to detect thrombin based on aptamer recognition, showing changes in optical appearance due to electrostatic interactions. By observing the optical changes of liquid crystals, thrombin could be analyzed with low cost and simple operation.
MICROCHEMICAL JOURNAL
(2021)
Review
Chemistry, Analytical
Zahra Salmasi, Nadiyeh Rouhi, Hossein Safarpour, Nozhat Zebardast, Hamed Zare
Summary: Thrombin, a key protein involved in hemostasis and tissue adhesion, is important in clinical detection. Aptasensors and nanoaptasensors based on DNAzymes have shown promise in accurate thrombin detection. This article reviews the progress made in DNAzyme-based aptasensors and nanoaptasensors for thrombin detection, and discusses the challenges and prospects in this field.
CRITICAL REVIEWS IN ANALYTICAL CHEMISTRY
(2022)
Article
Engineering, Chemical
Yanna Lin, Yulong Xu, Yanzhi Xing, Nazhen Liu, Xuwei Chen
Summary: This study develops a smart gating membrane using membrane separation technique for the selective separation and extraction of thrombin from complex matrices. The membrane exhibits temperature-controlled size-screening effect and excellent thrombin capturing specificity, resulting in high separation efficiency and preserved biological activity of thrombin.
JOURNAL OF MEMBRANE SCIENCE
(2023)
Article
Engineering, Chemical
Jinglei Liu, Tianfei Chu, Mengmeng Cheng, Yan Su, Guizheng Zou, Shifeng Hou
Summary: An efficient chiral separation membrane was fabricated using bovine serum albumin (BSA) modified graphene oxide (GO) through EDC/NHS coupling chemistry. The BSA modified membrane successfully separated Phe racemate, achieving up to 96.1% excess enantiomer (ee) in the osmotic solution under optimal conditions. The addition of BSA not only increased the spacing in the membrane, but also created chiral channels for selective transport of L-Phe, resulting in high flux and selectivity. The microstructure of BSA was found to be crucial for the chiral separation performance of the membrane, as unfolding of its helical and globular three-dimensional structures weakened or eliminated the separation performance. Molecular docking simulation experiments supported this conclusion.
JOURNAL OF MEMBRANE SCIENCE
(2023)
Article
Chemistry, Physical
Prashant Gargh, Abhishek Sarkar, Yu Hui Lui, Sheng Shen, Chao Hu, Shan Hu, Ikenna C. Nlebedim, Pranav Shrotriya
Summary: The study shows that lithium plating damages the solid electrolyte interface but reforms during relaxation, causing impedance changes in batteries. Additionally, the measured capacity loss is linearly correlated with impedance changes, suggesting impedance monitoring can be used for predicting the health status of Li-ion batteries.
JOURNAL OF POWER SOURCES
(2021)
Article
Materials Science, Multidisciplinary
Menglei Zhao, Jian Guo, Jingnan Zhao, Zhiquan Guo, Pranav Shrotriya, Yuanchen Cui, Zeng Yang
Summary: This study focuses on the preparation of superhydrophobic surfaces on metal by nanosecond laser etching and heat treatment. It was found that heat treatment can promote the transition from superhydrophilic to superhydrophobic surface and shorten the transition time. The optimal process parameters are a heating temperature of 150 degrees C and heating time of 1.5 hours.
JOURNAL OF MATERIALS ENGINEERING AND PERFORMANCE
(2022)
Article
Nanoscience & Nanotechnology
Sivaranjani Devarakonda, Baskar Ganapathysubramanian, Pranav Shrotriya
Summary: The study presents an experimental and computational approach for developing a highly sensitive and responsive label-free biosensor based on aptamer-functionalized transparent electrode. The sensor shows sensitive and specific thrombin protein detection with a high signal-to-noise ratio. Computational and experimental results indicate that the sensing response is due to modified ionic transport under the combined influence of steric hindrance and surface charge modification.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Materials Science, Multidisciplinary
Abhishek Sarkar, Pranav Shrotriya, Ikenna C. Nlebedim
Summary: This study investigates the impact of temperature on the performance of lithium batteries with graphite anodes, using a degradation model to evaluate the effects of charging rates, operating temperatures, and electrode design parameters on performance fade. The results predict severe capacity loss due to lithium plating at low temperatures, and rapid capacity loss due to accelerated SEI formation at high temperatures. Simulation results are used to identify optimal operating conditions and electrode design parameters for improving battery performance.
COMPUTATIONAL MATERIALS SCIENCE
(2022)
Article
Electrochemistry
Sivaranjani Devarakonda, Sungu Kim, Baskar Ganapathysubramanian, Pranav Shrotriya
Summary: Monitoring electrochemical impedance changes in functionalized nanochannels can be used for chemical and biological sensors. By modeling ionic current and predicting impedance changes, sensor performance can be evaluated and portable diagnostic devices can be designed.
ELECTROCHIMICA ACTA
(2022)
Article
Chemistry, Medicinal
Meric Ozturk, Marit Nilsen-Hamilton, Muslum Ilgu
Summary: Neurological diseases are a major global health concern affecting over a billion people, with limited diagnosis and treatment options available. Aptamers, as small nucleic acid molecules that are easy to modify chemically, hold promise for future diagnostics and therapeutics for these diseases.
Review
Chemistry, Analytical
Agnivo Gosai, Kamil Reza Khondakar, Xiao Ma, Md Azahar Ali
Summary: Biosensors have the potential to transform personalized medicine and environmental monitoring, with functional graphene being a popular choice for sensing material due to its ease of synthesis, high functionality, and large surface area for sensitive applications. The review highlights the current state-of-the-art biosensors based on graphene, emphasizing on the mechanism of sensing and future prospects in healthcare and environmental monitoring, particularly in additive manufacturing technologies like 3D printing.
Article
Biochemistry & Molecular Biology
Sharif Anisuzzaman, Ivan M. Geraskin, Muslum Ilgu, Lee Bendickson, George A. Kraus, Marit Nilsen-Hamilton
Summary: The interaction between nucleic acids and molecular targets involves structural reorganization. Understanding this interaction is important for drug development. Polyfluorophenyl modifications have been found to enhance the ability of small molecule drugs to disrupt local RNA structures and promote remodeling.
Article
Chemistry, Physical
Abhishek Sarkar, Pranav Shrotriya, Ikenna C. Nlebedim
Summary: Interfacial reaction mechanisms at the anode/separator interface play a crucial role in the performance and safety of lithium-ion batteries during fast charging. The study investigates the evolution and interactions of aging mechanisms at the anode/separator interface in lithium cobalt oxide/graphite pouch cells charged at variable rates. It is found that fast charging leads to incremental lithium loss and capacity fade, but the magnitude of capacity fade reduces with the number of cycles. XPS and SEM analyses reveal electrolyte decomposition, increase in lithium concentration, dendritic lithium growth on the anode surface, and film fracture as the mechanisms involved.
ACS APPLIED ENERGY MATERIALS
(2022)
Article
Engineering, Environmental
Abhishek Sarkar, Pranav Shrotriya, Ikenna C. Nlebedim
Summary: This article introduces a process of lithium recovery using lithium plating, which allows for the extraction of metallic lithium at room temperature using water. Experimental results show a 37% improvement in lithium recovery rate with fast charging. This process also enables the recovery of high-purity graphite and transition metal oxides.
Article
Biochemistry & Molecular Biology
Dilini Singappuli-Arachchige, Shuren Feng, Lijun Wang, Pierre E. Palo, Samuel O. Shobade, Michelle Thomas, Marit Nilsen-Hamilton
Summary: Magnetosomes of magnetotactic bacteria contain magnetic nanocrystals enclosed in vesicles. Mms6, a single magnetosome protein, has been found to direct the crystallization of magnetite nanoparticles in vitro. This study shows that Mms6 acts as a ferric reductase, reducing Fe3+ to Fe2+ to promote magnetite formation. The structure and multimeric state of Mms6 play a role in its iron reduction ability and iron binding characteristics.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Biochemical Research Methods
Niloofar Yousefi, Mehdi Yazdani-Jahromi, Aida Tayebi, Elayaraja Kolanthai, Craig J. Neal, Tanumoy Banerjee, Agnivo Gosai, Ganesh Balasubramanian, Sudipta Seal, Ozlem Ozmen Garibay
Summary: In this study, a deep learning-based framework called BindingSite-AugmentedDTA is proposed to improve the prediction of drug-target affinity. The framework reduces the search space of potential-binding sites, enhances prediction performance, and provides interpretability. Computational results and experimental validation support the potential of this framework in drug repurposing.
BRIEFINGS IN BIOINFORMATICS
(2023)
Article
Biochemistry & Molecular Biology
Soma Banerjee, Mahsa Askary Hemmat, Shambhavi Shubham, Agnivo Gosai, Sivaranjani Devarakonda, Nianyu Jiang, Charith Geekiyanage, Jacob A. Dillard, Wendy Maury, Pranav Shrotriya, Monica H. Lamm, Marit Nilsen-Hamilton
Summary: The Ebola virus glycoprotein (GP) gene produces several mRNAs that generate different proteins, including a transmembrane protein and two secreted glycoproteins. Three structurally distinct aptamers were selected to bind with the secreted glycoprotein (sGP) and the transmembrane protein (GP1,2). These aptamers showed high affinity and selectivity for sGP and GP1,2 and could detect them with high sensitivity in the presence of serum.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Meeting Abstract
Biochemistry & Molecular Biology
Soma Banerjee, Jan Hoinka, Agnivo Gosai, Zhichen Zhu, Sivaranjani Devarakonda, Charith Geekiyanage, Shambhavi Shubham, Nicholas Lennemann, Jake Dillard, Natalie Ruggio
Article
Biophysics
Reza Khodadadi, Manouchehr Eghbal, Hamideh Ofoghi, Alireza Balaei, Ali Tamayol, Karen Abrinia, Amir Sanati-Nezhad, Mohamadmahdi Samandari
Summary: This paper introduces an integrated portable centrifugal microfluidic system that automates cell and fluid manipulation for complete blood counting (CBC) analysis at the point-of-care (POC). The system utilizes a specially designed microfluidic disc for cell separation, solution metering and mixing, and cell counting, and is equipped with a custom script for automated quantification of cells. The proposed method shows a strong correlation with the gold standard hematology analyzer for various blood parameters. The portable system offers simplicity, affordability, and low power consumption, making it a potential solution for improving healthcare delivery in resource-limited settings and remote areas.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Nabil H. Bhuiyan, Joon S. Shim
Summary: Developing herd immunity is crucial for changing the course of the COVID-19 pandemic. An AI-driven point-of-care testing platform has been proposed for analyzing the body's response to SARS-CoV-2, and it has been successfully used for quantifying viral proteins and antibodies in blood samples. A data-receptive web-based dashboard system has also been developed for real-time analysis of herd immunity progress.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Alexiane Godain, Timothy M. Vogel, Pascal Fongarland, Naoufel Haddour
Summary: This study provides comprehensive insights into the intricate relationship between shear stress and electroactive biofilms in microbial fuel cells, highlighting the pivotal role of shear stress in influencing the growth kinetics, electrical performance, and physical structure of the biofilms. The study also emphasizes the complexities of extracellular electron transfer mechanisms and the need for complementary metaproteomic analyses.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Linjie Wang, Yixin Chen, Yang Ji, Shujun Zheng, Fei Wang, Caolong Li
Summary: A paper-based biosensor incorporating surface-enhanced Raman spectroscopy (SERS) and colorimetric detection has been developed for efficient quantification of intracellular glutathione (GSH). The biosensor exhibits excellent selectivity, stability, and precision, with low detection limits in both SERS and colorimetric modes. It has been successfully utilized for intracellular GSH detection and validated against a commercial GSH assay kit.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Quan Zhou, Jing Wang, Zhen Zhang, Alain Wuethrich, Richard J. Lobb, Matt Trau
Summary: This study presents a biosensor for sensitive detection of EMT-associated biomarkers on extracellular vesicles (EVs) surfaces during targeted therapy. Through longitudinal monitoring of patients, the biosensor shows its ability to identify the EMT-like phenotype switching on circulating EVs during the development of resistance.
BIOSENSORS & BIOELECTRONICS
(2024)
Review
Biophysics
Pratika Rai, Sabrina N. Hoba, Celine Buchmann, Robert J. Subirana-Slotos, Christian Kersten, Tanja Schirmeister, Kristina Endres, Bernd Bufe, Alexey Tarasov
Summary: Proteases have been proposed as potential biomarkers for various pathological conditions. The development of protease biosensors offers a more efficient way to investigate dysregulated proteases. This review article presents different optical and electrochemical detection methods for designing biosensors for all major protease families.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Chengxin Liu, Xu Shen, Li Yan, Runlian Qu, Yue Wang, Yaqin He, Zixuan Zhan, Piaopiao Chen, Feng Lin
Summary: In this study, a homogeneous rapid electrochemical aptasensor was developed to quantitatively detect CTCs in lung cancer patients. The aptasensor utilized a DNA nanosphere structure and a complementary aptamer to specifically detect mucin 1 as a marker for CTCs. The assay exhibited high specificity and sensitivity, and the results were consistent with other detection methods.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Danni Xue, Xing Dai, Jialong Zhao, Jiayao Zhang, Huan Liu, Kui Liu, Tao Xu, Chenjie Gu, Xingfei Zhou, Tao Jiang
Summary: In this study, a dual-enhancement SERS substrate based on Ti3C2TX and Ag nanocubes was fabricated for precise quantification of ritonavir and ibrutinib in serum. The formation of numerous electromagnetic hotspots between Ag nanocubes facilitated effective photo-induced charge transfer. The composite substrate showed excellent sensitivity, achieving low detection limits and high recoveries, making it promising for monitoring and identification of clinical blood drug concentration.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Tenghua Zhang, Zihui Xie, Xiaohe Zheng, Yuxin Liang, Yao Lu, Hankang Zhong, Feiyang Qian, Yuqing Zhu, Ruiting Sun, Yan Sheng, Jiaming Hu
Summary: This study reports a technology based on cationic lipid-polymer hybrid nanoparticles for efficient extracellular vesicle (EV) enrichment and in-situ detection of internal microRNAs. The technology demonstrates high EV enrichment efficiency and sensitive internal RNA detection, making it potentially useful for early pancreatic cancer diagnosis.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Wenjie Dai, Gaoxu Chen, Xiaoyan Wang, Shujun Zhen, Chengzhi Huang, Lei Zhan, Yuanfang Li
Summary: In this study, a novel metal organic gel (MOG) with dual electrochemiluminescence (ECL) properties was prepared by simple mixing. The MOG exhibited strong and stable anodic and cathodic ECL signals. By utilizing this MOG, an ECL resonance energy transfer (ECL-RET) biosensor was constructed for ultrasensitive detection of a specific gene. The study developed a straightforward technique for obtaining a single luminescent material with dual signals and expanded the analytical application of MOGs in the realm of ECL.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Lais Canniatti Brazaca, Amanda Hikari Imamura, Rodrigo Vieira Blasques, Jessica Rocha Camargo, Bruno Campos Janegitz, Emanuel Carrilho
Summary: The use of microfluidic paper-based analytical devices (muPADs) for medical diagnosis is a growing trend due to their low cost, easy use, simple manufacturing, and potential for application in low-resource settings. This review focuses on the advances in muPADs for medical diagnostics, discussing their use in detecting various biomarkers in common human biofluids. The challenges of biomarker detection in each sample are examined, along with innovative techniques to overcome these limitations. The commercialization difficulties of muPADs are also considered, along with future trends such as wearable devices and integrated platforms.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Minghong Jian, Xudong Sun, Hua Zhang, Xiaotong Li, Shasha Li, Zhenxin Wang
Summary: Matrix metalloproteinases (MMPs) are attractive biomarkers for cancer diagnosis and treatment, but their low abundance in biological samples, especially in the early stages of tumors, makes it challenging to precisely analyze MMP activities. In this study, a peptide microarray-based metal-enhanced fluorescence assay (PMMEFA) is proposed as a sensitive and specific method to simultaneously detect MMP-1, -2, -3, -7, -9, and -13 activities. The PMMEFA showed excellent sensitivity and was capable of detecting MMP activities in various matrices.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Kyung Ho Kim, Eunsu Ryu, Zinah Hilal Khaleel, Sung Eun Seo, Lina Kim, Yong Ho Kim, Hyun Gyu Park, Oh Seok Kwon
Summary: We have developed a novel strategy for discriminative detection of SARS-CoV-2 variants using the plasmonic photothermal effect of gold nanofilms and digital polymerase chain reaction (dPCR) technology. With this method, we were able to detect the delta and omicron variants with high sensitivity within 25 minutes from COVID-19 patients' clinical samples, making it a rapid and accurate point-of-care testing tool.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Zepeng Kang, Yuanming Wang, Haiyan Song, Xueli Wang, Job Zhang, Zhiguang Zhu
Summary: By designing a wearable and flexible lactic-acid/O2 EBFC with an air-breathing biocathode, the limitations of biocathode are effectively solved. The optimal performance conditions are determined through experiments, and the EBFC is successfully applied to power a low-power device.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Huayun Chen, Zhiheng You, Yuhui Hong, Xiao Wang, Mingming Zhao, Yushi Luan, Yibin Ying, Yixian Wang
Summary: This study developed a colorimetric sensor array using gas-responsive two-dimensional metal-organic framework (MOF) composites for highly sensitive detection of volatile organic compounds (VOCs). The dye/Zn-2(bim)(4) composites-based sensor arrays showed enhanced sensitivity and anti-interference properties. The findings demonstrate the potential use of dye/Zn-2(bim)(4) sensor arrays for early perception of plant diseases.
BIOSENSORS & BIOELECTRONICS
(2024)
