Genomic Accumulation of Retrotransposons Was Facilitated by Repressive RNA-Binding Proteins: A Hypothesis

A LINE1-Nucleolin Partnership Regulates Early Development and ESC Identity

(2018) Michelle Percharde et al.   CELL

Integrated analysis sheds light on evolutionary trajectories of young transcription start sites in the human genome

(2018) Cai Li et al.   GENOME RESEARCH

Dissection of affinity captured LINE-1 macromolecular complexes

(2018) Martin S Taylor et al.   eLife

Dynamic evolution of regulatory element ensembles in primate CD4+ T cells

(2018) Charles G. Danko et al.   Nature Ecology & Evolution

Hijacking Oogenesis Enables Massive Propagation of LINE and Retroviral Transposons

(2018) Lu Wang et al.   CELL

Heteromeric RNP Assembly at LINEs Controls Lineage-Specific RNA Processing

(2018) Jan Attig et al.   CELL

Uridylation by TUT4/7 Restricts Retrotransposition of Human LINE-1s

(2018) Zbigniew Warkocki et al.   CELL

Alu insertion variants alter mRNA splicing

(2018) Lindsay M Payer et al.   NUCLEIC ACIDS RESEARCH

Similar Evolutionary Trajectories for Retrotransposon Accumulation in Mammals

(2017) Reuben M. Buckley et al.   Genome Biology and Evolution

Selective silencing of euchromatic L1s revealed by genome-wide screens for L1 regulators

(2017) Nian Liu et al.   NATURE

DHX9 suppresses RNA processing defects originating from the Alu invasion of the human genome

(2017) Tuğçe Aktaş et al.   NATURE

KRAB zinc-finger proteins contribute to the evolution of gene regulatory networks

(2017) Michaël Imbeault et al.   NATURE

Complexity and conservation of regulatory landscapes underlie evolutionary resilience of mammalian gene expression

(2017) Camille Berthelot et al.   Nature Ecology & Evolution

Control of HIV-1 gene expression by SR proteins

(2016) Charlotte Mahiet et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Identification of the long, edited dsRNAome of LPS-stimulated immune cells

(2016) Matthew G. Blango et al.   GENOME RESEARCH

Regulatory activities of transposable elements: from conflicts to benefits

(2016) Edward B. Chuong et al.   NATURE REVIEWS GENETICS

ADAR1 restricts LINE-1 retrotransposition

(2016) Elisa Orecchini et al.   NUCLEIC ACIDS RESEARCH

Regulatory evolution of innate immunity through co-option of endogenous retroviruses

(2016) E. B. Chuong et al.   SCIENCE

Splicing repression allows the gradual emergence of new Alu-exons in primate evolution

(2016) Jan Attig et al.   eLife

Restricting retrotransposons: a review

(2016) John L. Goodier   Mobile DNA

Isoforms of RNA-Editing Enzyme ADAR1 Independently Control Nucleic Acid Sensor MDA5-Driven Autoimmunity and Multi-organ Development

(2015) Kathleen Pestal et al.   IMMUNITY

Retrotransposition and Crystal Structure of an Alu RNP in the Ribosome-Stalling Conformation

(2015) Valentina Ahl et al.   MOLECULAR CELL

A 3′ Poly(A) Tract Is Required for LINE-1 Retrotransposition

(2015) Aurélien J. Doucet et al.   MOLECULAR CELL

Evidence for cooperative tandem binding of hnRNP C RRMs in mRNA processing

(2015) Zuzana Cieniková et al.   RNA

RNA editing by ADAR1 prevents MDA5 sensing of endogenous dsRNA as nonself

(2015) B. J. Liddicoat et al.   SCIENCE

Uridylation by TUT4 and TUT7 Marks mRNA for Degradation

(2014) Jaechul Lim et al.   CELL

Stable C0T-1 Repeat RNA Is Abundant and Is Associated with Euchromatic Interphase Chromosomes

(2014) Lisa L. Hall et al.   CELL

Dodging two bullets with one dsRNA-binding protein

(2014) Reyad A Elbarbary et al.   CELL CYCLE

Evolutionally dynamic L1 regulation in embryonic stem cells

(2014) N. Castro-Diaz et al.   GENES & DEVELOPMENT

MOV10 Is a 5′ to 3′ RNA Helicase Contributing to UPF1 mRNA Target Degradation by Translocation along 3′ UTRs

(2014) Lea H. Gregersen et al.   MOLECULAR CELL

An evolutionary arms race between KRAB zinc-finger genes ZNF91/93 and SVA/L1 retrotransposons

(2014) Frank M. J. Jacobs et al.   NATURE

Deep transcriptome profiling of mammalian stem cells supports a regulatory role for retrotransposons in pluripotency maintenance

(2014) Alexandre Fort et al.   NATURE GENETICS

Genome-wide analysis of Alu editability

(2014) L. Bazak et al.   NUCLEIC ACIDS RESEARCH

The RNA-Editing Enzyme ADAR1 Controls Innate Immune Responses to RNA

(2014) Niamh M. Mannion et al.   Cell Reports

Affinity Proteomics Reveals Human Host Factors Implicated in Discrete Stages of LINE-1 Retrotransposition

(2013) Martin S. Taylor et al.   CELL

Direct Competition between hnRNP C and U2AF65 Protects the Transcriptome from the Exonization of Alu Elements

(2013) Kathi Zarnack et al.   CELL

STAU1 binding 3' UTR IRAlus complements nuclear retention to protect cells from PKR-mediated translational shutdown

(2013) R. A. Elbarbary et al.   GENES & DEVELOPMENT

β-Thalassemia Due to Intronic LINE-1 Insertion in theβ-GlobinGene (HBB): Molecular Mechanisms Underlying Reduced Transcript Levels of theβ-GlobinL1Allele

(2013) Lucie Lanikova et al.   HUMAN MUTATION

Mapping the LINE1 ORF1 protein interactome reveals associated inhibitors of human retrotransposition

(2013) John L. Goodier et al.   NUCLEIC ACIDS RESEARCH

Genome-wide analysis of Staufen-associated mRNAs identifies secondary structures that confer target specificity

(2013) John D. Laver et al.   NUCLEIC ACIDS RESEARCH

The Placental Mammal Ancestor and the Post-K-Pg Radiation of Placentals

(2013) M. A. O'Leary et al.   SCIENCE

ADAR Regulates RNA Editing, Transcript Stability, and Gene Expression

(2013) Isabel X. Wang et al.   Cell Reports

Transposable Elements Re-Wire and Fine-Tune the Transcriptome

(2013) Michael Cowley et al.   PLoS Genetics

Active Transposition in Genomes

(2012) Cheng Ran Lisa Huang et al.   Annual Review of Genetics

The Poly(A)-Binding Protein Nuclear 1 Suppresses Alternative Cleavage and Polyadenylation Sites

(2012) Mathias Jenal et al.   CELL

TRIM28 repression of retrotransposon-based enhancers is necessary to preserve transcriptional dynamics in embryonic stem cells

(2012) H. M. Rowe et al.   GENOME RESEARCH

RNA Targets and Specificity of Staufen, a Double-stranded RNA-binding Protein inCaenorhabditis elegans

(2012) Jacqueline Baca LeGendre et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

APOBEC3G Inhibits MicroRNA-mediated Repression of Translation by Interfering with the Interaction between Argonaute-2 and MOV10

(2012) Chao Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Poly(A) Binding Protein C1 Is Essential for Efficient L1 Retrotransposition and Affects L1 RNP Formation

(2012) L. Dai et al.   MOLECULAR AND CELLULAR BIOLOGY

hnRNPL and nucleolin bind LINE-1 RNA and function as host factors to modulate retrotransposition

(2012) Suresh Peddigari et al.   NUCLEIC ACIDS RESEARCH

Endogenous MOV10 inhibits the retrotransposition of endogenous retroelements but not the replication of exogenous retroviruses

(2012) Shetal Arjan-Odedra et al.   Retrovirology

MOV10 RNA Helicase Is a Potent Inhibitor of Retrotransposition in Cells

(2012) John L. Goodier et al.   PLoS Genetics

Coevolution of retroelements and tandem zinc finger genes

(2011) J. H. Thomas et al.   GENOME RESEARCH

Gene regulation by SINES and inosines: biological consequences of A-to-I editing of Alu element inverted repeats

(2010) Ling-Ling Chen et al.   CELL CYCLE

KAP1 controls endogenous retroviruses in embryonic stem cells

(2010) Helen M. Rowe et al.   NATURE

iCLIP reveals the function of hnRNP particles in splicing at individual nucleotide resolution

(2010) Julian König et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Transposable elements in gene regulation and in the evolution of vertebrate genomes

(2009) Guillaume Bourque   CURRENT OPINION IN GENETICS & DEVELOPMENT

Endogenous retroviral LTRs as promoters for human genes: A critical assessment

(2009) Carla J. Cohen et al.   GENE

Transposable elements in disease-associated cryptic exons

(2009) Igor Vorechovsky   HUMAN GENETICS

Altered Nuclear Retention of mRNAs Containing Inverted Repeats in Human Embryonic Stem Cells: Functional Role of a Nuclear Noncoding RNA

(2009) Ling-Ling Chen et al.   MOLECULAR CELL

Retroviral promoters in the human genome

(2008) Andrew B. Conley et al.   BIOINFORMATICS

Alu element-mediated gene silencing

(2008) Ling-Ling Chen et al.   EMBO JOURNAL

Transposable elements and the evolution of regulatory networks

(2008) Cédric Feschotte   NATURE REVIEWS GENETICS

Phylogenetic analysis of mRNA polyadenylation sites reveals a role of transposable elements in evolution of the 3′-end of genes

(2008) Ju Youn Lee et al.   NUCLEIC ACIDS RESEARCH

Exon creation and establishment in human genes

(2008) André Corvelo et al.   GENOME BIOLOGY