Article
Chemistry, Multidisciplinary
Jinghao Yang, Wei Zhou, Jiaming Hu, Ruohan Jiang, Guangai Sun, Jie Zhao, Fei Wang, Fang Fang, Yun Song, Dalin Sun
Summary: All-solid-state alkali ion batteries are a future trend in battery technology, and can provide low-cost metal fluoride electrode materials if certain problems can be resolved. A liquid metal activation strategy is proposed, in which liquid Ga elements are generated in situ and doped into the LiF crystal structure. This strategy significantly increases the lithium-ion storage capacity of MnF2 by 87% and enhances the sodium-ion storage capacity of FeF3 by 33%.
ADVANCED MATERIALS
(2023)
Review
Electrochemistry
Meng Li, Hui Liu, Ligang Feng
Summary: Fluoridation has been found to play a significant role in the fabrication of oxygen evolution reaction catalysts, affecting structure transformation, surface engineering, electronic state tuning, and the formation and exposure of active phases. Various types of fluorine-containing catalysts have been developed, showing efficient active phase formation due to fluorine etching effect. This review discusses the advancements, challenges, and potential impacts of using fluoridation in catalyst fabrication for water-splitting reactions, aiming to provide guidance for the scientific community.
ELECTROCHEMISTRY COMMUNICATIONS
(2021)
Article
Materials Science, Multidisciplinary
Wen Liu, Sen Ma, Bingxin Wan, Yong Li, Rui Guo, Chao Wu, Shangde Ma, Haijuan Pei, Jingying Xie
Summary: For almost half a century, lithium/carbon fluorides (Li/CFx) batteries have been considered irreversible in liquid electrolyte, but they still have attractive features. Different metal/CFx batteries, including Li/CFx, Na/CFx, Mg/CFx, Al/CFx, and K/CFx batteries, have been developed. This review introduces the progress made in rechargeable metal/CFx batteries and proposes design rules for their development.
APPLIED MATERIALS TODAY
(2023)
Article
Chemistry, Multidisciplinary
Jieun Lee, Seung Ho Choi, Gahyeon Im, Kyu-Joon Lee, Taegeun Lee, Jihoon Oh, Nohjoon Lee, Hyuntae Kim, Yunsung Kim, Sangheon Lee, Jang Wook Choi
Summary: Anode-less electrodes in all-solid-state batteries have competitive energy densities and improved cycle life, but the composite matrices of these electrodes inhibit lithium-ion diffusion. This study utilizes the conversion reaction of metal fluorides, which induces alloying reactions with lithium ions and improves the uniformity and sustainability of lithium (de)plating.
ADVANCED MATERIALS
(2022)
Article
Chemistry, Applied
Qi-Wei Li, Xin-Yue Zhang, Lu Lu, Zi-Qian Wu, Ji Li, Gui-Zhi Li, Kai Sun, Shang-Dong Yang, Bin Yang
Summary: A TFAA/DMSO/NaF-based system has been developed for efficient fluorination of P(O)-H and P(O)-OH compounds. This novel method provides direct and compatible access to a variety of fluorophosphonates and phosphonofluoridates without the use of highly toxic and expensive fluorination reagents.
ADVANCED SYNTHESIS & CATALYSIS
(2022)
Article
Plant Sciences
Siarhei A. Dabravolski, Stanislav Isayenkov
Summary: Soil salinity is a major factor affecting the growth of agricultural crops. The evolution of plant Na+/K+-P-ATPases shows significant differences in domain architecture and subunit composition depending on plant taxa and environmental salinity. The gradual replacement of the Na+-binding site with the Ca2+-binding site during evolution is observed in various organisms.
Review
Chemistry, Physical
Lidong Sun, Yu Li, Wei Feng
Summary: This review discusses the potential and advantages of conversion-type metal fluorides as cathode materials for next-generation rechargeable batteries, as well as the issues and solutions, providing guidance for the development of MF cathode-based batteries.
Article
Materials Science, Multidisciplinary
Samuel J. Baxter, Jose Mendez-Arroyo, Jim Enterkin, Paul M. Alvey, Camille May, Clay Cox, Jianhua Yao
Summary: The highly porous and crystalline nature of MOFs has attracted attention for various applications in the energy industry. They have modular structures that allow modification of molecular and microstructural properties. This paper presents a thermal stability analysis of ligand-substituted MOF-808 derivatives, identifying the effects of structural changes on thermal cycling stability. The results show significant negative thermal expansion in MOF-808-SO4, suggesting that targeted ligand modifications can greatly impact the thermal stability and expansion of MOFs.
ACS MATERIALS LETTERS
(2022)
Article
Chemistry, Applied
Chen Chen, Jie Ding, Liying Liu, Yujie Huang, Bolin Zhu
Summary: The presented palladium-catalyzed domino cyclization/phosphorylation of gem-dibromoolefins utilizes H-phosphinates and secondary phosphine oxides as phosphine sources. Various phosphorylated heteroaromatics are obtained in moderate to good yields with broad functional group compatibility. This protocol enables multiple bond-forming events including C-X (X=O, N, S) and C-P bonds using readily available starting materials, and can be easily applied to large-scale preparation and late-stage functionalization.
ADVANCED SYNTHESIS & CATALYSIS
(2022)
Article
Chemistry, Physical
Tao Zhao, Dazhong Zhong, Lu Tian, Genyan Hao, Guang Liu, Jinping Li, Qiang Zhao
Summary: Designing high-efficiency electrocatalysts is crucial for addressing energy shortage and environmental pollution. In this study, Co8FeS8@CoFe-MOF/NF heterojunction arrays were fabricated by embedding sulfides into MOF nanosheets, which acted as a multifunctional electrocatalyst. The introduction of sulfide not only adjusted the electronic structure and surface properties, but also increased the active area for enhanced catalytic activity. The synthesized Co8FeS8@CoFe-MOF/NF exhibited excellent OER performance and UOR performance at low potentials. Moreover, the assembled two-electrode system demonstrated efficient overall water splitting and urea electrolysis.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2023)
Article
Biochemistry & Molecular Biology
Genesis Mantilla, Maria C. Perez-Gordones, Soledad Cisneros-Montufar, Gustavo Benaim, Juan-Carlos Navarro, Marta Mendoza, Jose R. Ramirez-Iglesias
Summary: This study analyzed the CaMBD of multiple Ca2+-ATPases and identified specific patterns and amino acid selections in different species. The results demonstrated a conserved mechanism for maintaining calcium homeostasis across evolution and provided insights for detecting potential CaMBDs.
JOURNAL OF MEMBRANE BIOLOGY
(2023)
Article
Chemistry, Multidisciplinary
Albert Dautov, Kotstantin Kotlyar, Denis Butusov, Ivan Novikov, Aliya Khafizova, Artur Karimov
Summary: This work investigates the synthesis of AlF(3) and one-dimensional structures based on AlF(3) through the reaction of initial aluminum with aqueous hydrofluoric acid solution. The morphology and surface of the obtained samples are analyzed using scanning electron microscopy and atomic force microscopy. Whiskers of one-dimensional structures are synthesized under the given conditions. Quantitative energy-dispersive X-ray spectroscopy is used for analysis.
Article
Materials Science, Multidisciplinary
Qing Shi, Qiao Liu, Yapeng Zheng, Yaqian Dong, Lin Wang, Hantao Liu, Weiyou Yang
Summary: Developed through one-step carbonization of a mixture of ZIF-67 and MPSA, bifunctional ORR/OER electrocatalysts based on CoxP@NPC can be rationally designed and fabricated in a controlled manner. Among these catalysts, Co2P@NPC exhibits the best bifunctional ORR/OER activity, leading to a zinc-air battery with high power density and stability.
ENERGY & ENVIRONMENTAL MATERIALS
(2022)
Article
Chemistry, Physical
Yuxiao Gao, Ying Zhao, Hongru Liu, Mingyu Shao, Zhi Chen, Tianyi Ma, Zexing Wu, Lei Wang
Summary: In this study, a Ru-Re3P4/NPC catalyst with porous nanostructure was prepared using a low-toxic material, which successfully regulated the electrocatalytic activity and improved the efficiency of the hydrogen evolution reaction.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2022)
Article
Chemistry, Multidisciplinary
Xiang Ma, Saurav Bhattacharya, Talha Nisar, Anja B. Mueller, Veit Wagner, Nikolai Kuhnert, Ulrich Kortz
Summary: We present the synthesis and structural characterization of the first Pd-IV-containing polyoxopalladate(ii) complex. This discrete mixed-valent polyoxopalladate(iv/ii) features a central Pd-IV ion surrounded by a six-membered Pd-II-oxo ring capped by six dimethylarsinate groups. The structure was analyzed using various techniques in the solid state, solution, and gas phase.
CHEMICAL COMMUNICATIONS
(2023)
Article
Pharmacology & Pharmacy
M. Ontiveros, D. Rinaldi, M. Marder, M. V. Espelt, I. Mangialavori, M. Vigil, J. P. Rossi, M. Ferreira-Gomes
BIOCHEMICAL PHARMACOLOGY
(2019)
Article
Chemistry, Medicinal
Damijan Knez, Natalia Colettis, Luca G. Iacovino, Matej Sova, Anja Pislar, Janez Konc, Samo Lesnik, Josefina Higgs, Fabiola Kamecki, Irene Mangialavori, Ana Dolsak, Simon Zakelj, Jurij Trontelj, Janko Kos, Claudia Binda, Mariel Marder, Stanislav Gobec
JOURNAL OF MEDICINAL CHEMISTRY
(2020)
Article
Physiology
Dylan J. Meyer, Sharan Bijlani, Marilina de Sautu, Kerri Spontarelli, Victoria C. Young, Craig Gatto, Pablo Artigas
JOURNAL OF GENERAL PHYSIOLOGY
(2020)
Article
Biochemistry & Molecular Biology
Nicolas A. Saffioti, Marilina de Sautu, Ana Sol Riesco, Mariela S. Ferreira-Gomes, Juan Pablo F. C. Rossi, Irene C. Mangialavori
Summary: The study investigated the structural changes of PMCA during the reaction cycle, revealing that calmodulin binds to E2P-like states and conformational changes occur during dephosphorylation. It was found that the hydrophobicity in the nucleotide-binding pocket decreases and the Ca2+ binding site becomes inaccessible to the extracellular medium. Finally, a model describing the conformational changes during the Ca2+ transport of PMCA was proposed.
BIOCHEMICAL JOURNAL
(2021)
Article
Biochemistry & Molecular Biology
Nicolas A. Saffioti, Natalia Lauri, Lucia Cane, Rodolfo Gonzalez-Lebrero, Karina Alleva, Isabelle Mouro-Chanteloup, Mariano A. Ostuni, Vanesa Herlax, Pablo Julio Schwarzbaum
Summary: In this study, we investigated the mechanism of action of alpha-hemolysin (HlyA) from E. coli in human erythrocytes. We found that HlyA induces erythrocyte swelling and hemolysis, which is enhanced by purinergic signaling. We proposed a mathematical model to explain the kinetics of HlyA activity and gained new insights into the signaling and cytotoxicity mediated by HlyA in erythrocytes.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Cell Biology
Pablo Carabias, Maria Espelt, Maria L. Bacigalupo, Paola Rojas, Luciana Sarrias, Ayelen Rubin, Nicolas A. Saffioti, Maria T. Elola, Juan P. Rossi, Carlota Wolfenstein-Todel, Gabriel A. Rabinovich, Maria F. Troncoso
Summary: GAL1, abundantly expressed in the tumor microenvironment, may promote chemoresistance in HCC cells by modulating P-gp protein expression.
CELL DEATH & DISEASE
(2022)
Article
Biochemical Research Methods
Nicolas Andres Saffioti, Cora Lilia Alvarez, Zaher Bazzi, Maria Virginia Gentilini, Gabriel Eduardo Gondolesi, Pablo Julio Schwarzbaum, Julieta Schachter
Summary: Intestinal epithelial cells play crucial roles in nutrient absorption, electrolyte secretion, and food digestion. The release of extracellular ATP from these cells can act as a warning signal to activate the immune defense against pathogens. The regulation of extracellular ATP is a complex network of reactions involving intracellular ATP release and the activity of ectoenzymes.
PLOS COMPUTATIONAL BIOLOGY
(2023)
Article
Multidisciplinary Sciences
Debora E. Rinaldi, Mallku Q. Ontiveros, Nicolas A. Saffioti, Maximiliano A. Vigil, Irene C. Mangialavori, Rolando C. Rossi, Juan P. Rossi, Maria V. Espelt, Mariela S. Ferreira-Gomes
Summary: Flavonoids in green tea, especially EGCG, have various effects on cellular processes such as apoptosis and oxidative stress. Studies have shown that EGCG is a potent inhibitor of PMCA activity, affecting calcium homeostasis in living cells.
Review
Biotechnology & Applied Microbiology
Nicolas Andres Saffioti, Elisabetta Ada Cavalcanti-Adam, Diego Pallarola
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2020)
Article
Toxicology
Mariela S. Ferreira-Gomes, Irene C. Mangialavori, Mallku Q. Ontiveros, Debora E. Rinaldi, Jorge Martiarena, Sandra V. Verstraeten, Juan Pablo F. C. Rossi
ARCHIVES OF TOXICOLOGY
(2018)
Article
Biochemistry & Molecular Biology
Philipp Grad, Katarina Edwards, Lars Gedda, Victor Agmo Hernandez
Summary: This study investigates the effects of polyethylene glycol-(PEG) modified lipids and gangliosides on the Ca2+ induced interaction between liposomes composed of palmitoyl-oleoyl phosphatidylethanolamine (POPE) and palmitoyl-oleoyl phosphatidylserine (POPS) at physiological ionic strength. The results show that naked liposomes tend to adhere, rupture, and collapse on each other's surfaces upon addition of Ca2+, eventually resulting in the formation of large multilamellar aggregates and bilayer sheets. However, the presence of gangliosides or PEGylated lipids leads to the formation of small, long-lived bilayer fragments/disks. PEGylated lipids seem to be more effective than gangliosides at stabilizing these structures. The study suggests that direct liposome-liposome fusion is not the dominating process triggered by Ca2+ in the systems studied.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
(2024)
Article
Biochemistry & Molecular Biology
Saurabh Saraswat, Archana Chugh
Summary: Cell penetrating peptides (CPP) are important tools for intracellular delivery of molecules. In this study, a novel marine-derived CPP from Engraulis japonicus, called Engraulisin, was reported. Engraulisin demonstrated successful cellular uptake and selective antimicrobial activity against Methicillin-resistant Staphylococcus aureus (MRSA), making it a potential candidate for drug delivery.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
(2024)
Article
Biochemistry & Molecular Biology
Emanuela Efodili, Ashlynn Knight, Maryem Mirza, Cedric Briones, Il-Hyung Lee
Summary: This study demonstrates the spontaneous transfer of small membrane-bound peptides between a supported lipid bilayer and giant unilamellar vesicles in vitro. The transfer occurs through the formation of hemi-fusion stalks and is limited to small peptides due to the highly curved structure of the stalk. This system provides a synthetic platform for studying peptide trafficking between synthetic membranes.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
(2024)
Article
Biochemistry & Molecular Biology
Yueqi Niu, Si Jia Chen, Jeffery B. Klauda
Summary: Macrophage membranes in the activated state are more tightly packed, exhibit increased chain order across lipid species, and form specific lipid clusters. These findings provide physiologically accurate models for future computational studies of macrophage membranes and their proteins.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
(2024)
Article
Biochemistry & Molecular Biology
Niki Baccile, Vincent Chaleix, Ingo Hoffmann
Summary: This study measured the bending rigidity of self-assembled structures formed by a new biobased glucolipid bioamphiphile using neutron spin-echo (NSE) technology. The results showed that the bending rigidity of these structures is lower or higher compared to phospholipid membranes, providing a new theoretical basis for the application of these new molecular systems.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
(2024)
Article
Biochemistry & Molecular Biology
Alain Bolano Alvares, Pablo E. A. Rodriguez, Gerardo D. Fidelio
Summary: The behavior of amphiphilic molecules at the air/water interface was studied to evaluate the arrangement formed in a confined area. The surface properties of zwitterionic DPPC lipid and A beta(1-40) amyloid peptide in mixed films were investigated at different temperatures. DPPC undergoes a phase transition depending on temperature and lateral pressure, which allows for the study of its influence on amyloid structure formation.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
(2024)
Article
Biochemistry & Molecular Biology
Lukasz Plachta, Marzena Mach, Magdalena Kowalska, Pawel Wydro
Summary: Resveratrol, a popular phytoalexin found in grapes and red wine, has beneficial effects on the cardiovascular system, exhibits antiviral, antibacterial, and antifungal properties, and may have therapeutic effects against cancer. This study investigates the interaction of resveratrol with model cell membranes, demonstrating changes in their physicochemical parameters and highlighting the role of cholesterol content in resveratrol incorporation. The findings suggest that the molecular mechanism of action of resveratrol may involve interactions with lipid rafts.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
(2024)
Article
Biochemistry & Molecular Biology
Edurne Rujas, Beatriz Apellaniz, Johana Torralba, David Andreu, Jose M. M. Caaveiro, Shixia Wang, Shan Lu, Jose L. Nieva
Summary: This study investigates the role of fusion peptide and Trp-rich membrane proximal external region in HIV-1 fusion and demonstrates that liposome-based formulations containing FP-MPER hybrid peptides can induce the production of specific neutralizing antibodies in rabbits. The results support the use of liposomes as vaccine carriers and the inclusion of lipid membranes in immunogens to elicit specific humoral responses.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
(2024)
Article
Biochemistry & Molecular Biology
Dailin Li, Dingyuan Shi, Lei Wang
Summary: G protein-gated inwardly rectifying potassium (GIRK) channels play a significant role in regulating cell excitability. This study investigated the ion permeation mechanism in GIRK2 mutants using molecular dynamic simulations and QM/MM methods. The results revealed the importance of a multi-ion distribution for ion conduction.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
(2024)
Article
Biochemistry & Molecular Biology
Max J. den Uijl, Arnold J. M. Driessen
Summary: Membrane protein insertion into and translocation across the bacterial cytoplasmic membrane are essential processes facilitated by the Sec translocon. The phospholipid dependence of membrane protein insertion has remained mostly unknown. This study reveals that the insertion of the mannitol permease MtlA into the membrane depends on the presence of phosphatidylglycerol and is stimulated by phosphatidylethanolamine.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
(2024)
Article
Biochemistry & Molecular Biology
Patrick Allen, Adam C. Smith, Vernon Benedicto, Abbas Abdulhasan, Vasanthy Narayanaswami, Enrico Tapavicza
Summary: We explore the stability, size, and structure of nanodiscs formed by the N-terminal domain of apolipoprotein E3 and a variable number of 1,2-dimyristoyl-sn-glycero-3-phosphocholine molecules. Our simulations suggest that nanodiscs containing 240 to 420 DMPC molecules are stable. The antiparallel configuration shows more protein-protein interactions and ionic contacts, as well as greater stability and rigidity compared to the parallel configuration.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
(2024)
Article
Biochemistry & Molecular Biology
Patrick M. Keating, Nicholas P. Schifano, Xinrui Wei, Matthew Y. Kong, Jinwoo Lee
Summary: Lassa virus (LASV) infection is dependent on the fusion of its viral membrane with the host cell membrane, and our study reveals that this fusion process involves pH-dependent conformational changes in the transmembrane domain of LASV. These findings provide valuable insights into the fusion mechanism of LASV and can be utilized in the design of therapeutics to combat Lassa virus infections and prevent its potential spread.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
(2024)
Article
Biochemistry & Molecular Biology
Ashley L. Bennett, Kristen N. Cranford, Austin L. Bates, Christopher R. Sabatini, Hee-Seung Lee
Summary: This study employed molecular dynamics simulations to elucidate the binding, folding, and insertion details of TP10W in the cell membrane. The simulations revealed that TP10W can translocate across the lipid membrane as a monomer, and the charged amino acid side chains can move between lipid leaflets. Comparison with point mutated variants demonstrated significant conformational changes due to charge distribution.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
(2024)
Article
Biochemistry & Molecular Biology
Jessica H. van Wonderen, Jason C. Crack, Marcus J. Edwards, Thomas A. Clarke, Gerhard Saalbach, Carlo Martins, Julea N. Butt
Summary: Electrogenic bacteria transfer excess respiratory electrons to metal oxide particles and electrodes through the MtrCAB complex. The crystal structure of MtrCAB from S. baltica OS185 was resolved, and liquid chromatography mass spectrometry was used to determine the mass values of the three proteins in purified MtrCAB complexes.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
(2024)
Review
Biochemistry & Molecular Biology
Yi-Ming Chen, Ching-Tai Lu, Chia-Wen Wang, Wolfgang B. Fischer
Summary: A series of dye ligands were ranked based on docking experiments, selecting the most suitable ligands for binding with different proteins. Additionally, a comparison study was conducted on a series of repurposing drugs and known antivirals.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
(2024)