Article
Chemistry, Applied
Stepan M. Korobkov, Kirill P. Birin, Aslan Yu. Tsivadze
Summary: The influence of porphyrin substituents and solvent effect on their photoactivity and photostability were studied and discussed in detail. Results showed non-linear dependence between photosensitizer and singlet oxygen concentration, and an empirical correlation between HOMO energies and observed rate constants.
Article
Chemistry, Analytical
Rajannya Sen, Liang Li, Alexander V. Zhdanov, Rafael D. L. Gaspar, Dmitri B. Papkovsky
Summary: This study evaluated four different detection platforms for phosphorescence lifetime (PLT) measurements. The results showed that the Victor 2 fluorescence reader produced stable but inaccurate readings at low PLT values, while the Cary Eclipse luminescence spectrometer was able to partly correct this issue. The Tpx3Cam camera-based macroscope and the confocal laser-scanning FLIM/PLIM microscope provided more accurate and informative PLT data.
SENSORS AND ACTUATORS B-CHEMICAL
(2022)
Article
Chemistry, Applied
Xue Li, Xinyu Cai, Qingzhi Zeng, Xueyan Ren, Qingjun Kong
Summary: Stilbenes, such as resveratrol, can effectively quench singlet oxygen (1O2). In this study, the quenching activities of different stilbenes were analyzed and compared, and it was found that catechol and carbon-carbon double bonds were key structures for quenching 1O2. This research provides insights for screening stilbenes with higher activities and the development of novel food-related antioxidants and functional foods.
Article
Chemistry, Analytical
Mozhgan Samandarsangari, Daria O. Kozina, Victor V. Sokolov, Anastasia D. Komarova, Marina V. Shirmanova, Ilya S. Kritchenkov, Sergey P. Tunik
Summary: In this study, new phosphorescent iridium complexes were synthesized with water-soluble and biocompatible properties. The major photophysical characteristics were determined by two cyclometallating ligands based on 2-pyridine-benzothiophene. The use of various diimine ligands influenced the quantum yield of phosphorescence and the sensitivity to oxygen. The complexes demonstrated low toxicity and good water solubility.
Article
Chemistry, Analytical
Fang Wang, Longfei Chen, Jiaomeng Zhu, Xuejia Hu, Yi Yang
Summary: The intelligent dissolved oxygen sensor presented in this study is based on phosphorescence quenching, with a high sensitivity oxygen-sensing membrane prepared on microfluidic channels. It offers continuous, intelligent, and real-time analysis of dissolved oxygen, achieving low detection limit, high sensitivity, and short response time. By combining optofluidics and electronics, the sensor provides a miniaturized and intelligent detection platform for practical oxygen analysis in various fields.
Article
Chemistry, Multidisciplinary
Jin Li, Lei Wang, Jinrong Li, Yujie Shao, Ziang Liu, Guangzhe Li, Engin U. Akkaya
Summary: Naphthalene endoperoxides are convenient sources of singlet oxygen but their potential as ground-state molecular oxygen carriers remains largely unexplored. A compound with a bimodular design, incorporating an endoperoxide and a physical quencher of singlet oxygen, produces exclusively ground-state molecular oxygen. This compound shows potential as a highly tunable and targetable oxygen carrier in cell culture experiments, enhancing and sustaining cell proliferation.
CHEMISTRY-A EUROPEAN JOURNAL
(2022)
Article
Chemistry, Multidisciplinary
Rania E. Morsi, Denis Gentili, Franco Corticelli, Vittorio Morandi, Alberto Figoli, Francesca Russo, Francesco Galiano, Giovanna Angela Gentilomi, Francesca Bonvicini, Ilse Manet, Barbara Ventura
Summary: The development of polymeric fabrics with photoinduced antibacterial activity is crucial for various applications. In this study, cellulose acetate membranes were prepared with the addition of additives, including a photosensitizer (TPP), a surfactant (Pluronic F-127), and graphene oxide (GO). The combination of these three additives exhibited excellent antibacterial properties.
Article
Optics
Lixin Zang, Huibin Wang, Zongxue Wang, Shumin Wang, Miaomiao Yu, Qi Kang, Guizheng Zou, Huimin Zhao
Summary: This study reveals the competition between the triplet state of metalloporphyrins and surrounding oxygen, and regulates the phosphorescence intensity and singlet oxygen generation efficiency by using imidazole as a triplet protector.
JOURNAL OF LUMINESCENCE
(2022)
Article
Chemistry, Multidisciplinary
Tingting Xu, Chen Wang, Sijie Jiang, Tingting Yang, Xueming Wu
Summary: An effective approach to biotransform luteolin glycosides in hydrophilic organic solvents was developed using Bacillus cereus A46 cells. The addition of DMSO greatly enhanced the solubility of luteolin and regulated the formation of the desired product of luteolin 7-O-beta-glucoside.
Article
Engineering, Environmental
Limiao Cai, Qian Yao, Xiaodong Du, Jiayi Zhong, Haijian Lu, Xueqin Tao, Jiangmin Zhou, Zhi Dang, Guining Lu
Summary: A 1O2 system using FFA as a probe was constructed to discuss the quenching, interference elimination, and pollutant degradation ability of 1O2. The results revealed the influence of quencher dosage and ability on quenching, and provided a method to judge the interruption of 1O2 production.
JOURNAL OF HAZARDOUS MATERIALS
(2023)
Article
Materials Science, Ceramics
Lixia Yang, Yating Fu, Weilun Cheng, Di Peng, Zhaofeng Chen, Lirong Luo, Xiaofeng Zhao, Yingzheng Liu, Zongde Kou
Summary: This study investigates the phosphorescence properties of YSZ: Eu3+, Er3+ phosphors as a function of oxygen partial pressure and temperature. The results show that the phosphorescence intensity and lifetime of Eu3+ bands are sensitive to both oxygen partial pressure and temperature when temperature exceeds 400°C. In contrast, the phosphorescence intensity and lifetime of Er3+ bands are temperature-sensitive but oxygen-insensitive. Two measurement strategies are proposed including an intensity ratio method and a lifetime method.
CERAMICS INTERNATIONAL
(2023)
Article
Chemistry, Multidisciplinary
Kiho Nishioka, Mizuki Tanaka, Hayato Fujimoto, Toru Amaya, Sensuke Ogoshi, Mamoru Tobisu, Shuji Nakanishi
Summary: In addition to sufficient tolerance against superoxide radical attack, other factors also play a crucial role in the cyclability of Li-O2 batteries. The use of N,N-dimethylacetamide-based electrolyte can enhance the cyclability by quenching O-1(2) and forming highly decomposable Li2O2.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2022)
Article
Chemistry, Analytical
Mozhgan Samandarsangari, Ilya S. Kritchenkov, Daria O. Kozina, Anastasia D. Komarova, Marina V. Shirmanova, Sergey P. Tunik
Summary: The design, synthesis, and investigation of new molecular oxygen probes for bioimaging, based on phosphorescent transition metal complexes, have been studied. Three new iridium complexes with different ligands have been synthesized and characterized. These complexes exhibited phosphorescence and showed potential for use in bioimaging experiments. Furthermore, they were found to be internalized into cancer cells and localized in mitochondria and lysosomes.
Article
Spectroscopy
Honglin Zhang, Ting Liu, Xiyu Zhang, Hua Zhao, Yangdong Zheng, Feng Qin, Zhiguo Zhang, Tianqi Sheng, Ye Tian
Summary: The phosphorescence properties of PtOEP-C6/Poly (St-co-TFEMA) were investigated to accurately determine the oxygen content, revealing a strong temperature sensitivity. The correlation between oxygen content and phosphorescence intensity ratio can be accurately described by the Stern-Volmer equation, and a temperature correction method was developed using the obtained monotonic quenching constant K-SV. Additionally, the temperature quenching mechanism of PtOEP was clarified through time-resolved spectroscopy, showing that the enhanced quenching effect of oxygen by temperature is the cause of the temperature sensitivity in phosphorescence.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2021)
Article
Health Care Sciences & Services
Steffen Hackbarth, Rayhanul Islam, Vladimir Subr, Tomas Etrych, Jun Fang
Summary: This study investigates the impact of illumination intensity on singlet oxygen generation in tumor tissue. The results reveal that excessive illumination hinders singlet oxygen production, while lower intensity illumination can generate singlet oxygen in areas beyond blood vessels and walls. This finding has significant implications for tumor diagnosis using photosensitizers.
JOURNAL OF PERSONALIZED MEDICINE
(2022)
Article
Optics
A. S. Kozlov, O. N. Egorova, O. Medvedkov, A. A. Krasnovsky
Summary: The study observed population of the chemically active singlet state of molecular oxygen through direct laser excitation, using a chemical trapping method and spectroscopic analysis to monitor the generation of singlet oxygen. The results are important for both spectroscopy of oxygen and mechanistic studies of biological and therapeutic action of laser radiation.
Article
Optics
A. S. Benditkis, A. S. Kozlov, S. E. Goncharov, A. A. Krasnovsky
Summary: The study focused on IR phosphorescence and chemical trapping of oxygen in aerated organic solvents under laser irradiation, comparing the absorption spectra of dissolved oxygen molecules at different excitation wavelengths. The experiments revealed the presence of complexes that were more photoactive than oxygen molecules themselves. Phosphorescence of singlet oxygen was weaker under excitation at 690 nm compared to 765 nm, with linear dependence on excitation power and enhancement in solvents containing heavy atoms. The data provided evidence that the phosphorescence at 690 nm was due to excitation of the Fraunhofer band B in the oxygen absorption spectrum, with estimated molar absorption coefficients in aerated solvents lacking heavy atoms.
JOURNAL OF THE OPTICAL SOCIETY OF AMERICA B-OPTICAL PHYSICS
(2021)
Article
Biochemistry & Molecular Biology
Antonina Klimenko, Elvira E. Rodina, Denis Silachev, Maria Begun, Valentina A. Babenko, Anton S. Benditkis, Anton S. Kozlov, Alexander A. Krasnovsky, Yuri S. Khotimchenko, Vladimir L. Katanaev
Summary: Photodynamic therapy (PDT) is a powerful anticancer treatment that relies on the use of photosensitizers. This study identifies ETPA as a major metabolite of the North Pacific brittle stars and demonstrates its strong phototoxicity against cancer cell lines in vitro. In a mouse model of glioblastoma, ETPA injection combined with red laser irradiation induces necrotic ablation of the brain tumor.
Article
Optics
P. N. Antokhin, V. G. Arshinova, M. Yu Arshinov, B. D. Belan, S. B. Belan, L. P. Golobokova, D. K. Davydov, G. A. Ivlev, A. Kozlov, A. S. Kozlov, V. Otmakhov, T. M. Rasskazchikova, D. Simonenkov, G. N. Tolmachev, A. Fofonov
Summary: Airborne sensing data are used to study the change in air composition during the transition from the troposphere to the stratosphere. The study shows significant differences in the concentrations of different gases and particles, as well as variations in composition between different atmospheric layers.
ATMOSPHERIC AND OCEANIC OPTICS
(2021)
Article
Physics, Multidisciplinary
A. A. Krasnovsky, A. S. Kozlov, A. S. Benditkis
Summary: The results of studies on the photochemical activity and phosphorescence of oxygen molecules upon direct laser excitation in aerated organic solvents and water are summarized in this paper. The absorption spectra of dissolved oxygen in these media, obtained at normal pressure and temperature in the range of 600-1300 nm, are of fundamental importance for understanding the spectroscopy of molecular oxygen and its role as a photoreceptor triggering the biological action of laser radiation.
RUSSIAN PHYSICS JOURNAL
(2022)
Editorial Material
Biophysics
Larissa A. Koppel, Alexander A. Krasnovsky Jr
BIOPHYSICAL REVIEWS
(2022)
Article
Biochemistry & Molecular Biology
Alexander M. Firsov, Juergen Pfeffermann, Anton S. Benditkis, Tatyana I. Rokitskaya, Anton S. Kozlov, Elena A. Kotova, Alexander A. Krasnovsky, Peter Pohl, Yuri N. Antonenko
Summary: The goal of developing chemical compounds that can mimic the functions of biological molecular machineries has resulted in the creation of various artificial molecular motors (AMMs). These photoexcited monomolecular unidirectionally-rotating AMMs have been seen as potentially useful in pharmaceutical applications due to their ability to permeabilize biological membranes. However, the mechanical properties of lipid membranes cast doubt on the proposed drilling activity of AMMs. In this study, it was discovered that singlet oxygen released by a photoexcited molecular drill could oxidize unsaturated lipids in giant unilamellar vesicles, while liposomes made of saturated lipids remained unaffected. Further experiments showed that rather than mechanically destroying ion channels in lipid membranes, the AMMs photoinactivated them. This study suggests that the envisioned therapeutic and pharmaceutical applications of AMMs rely more on their photodynamic activity than their nanomechanical drilling abilities.
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY
(2023)
Article
Optics
I. S. Andreeva, O. A. Baturina, A. S. Safatov, N. A. Solovyanova, T. Y. Alikina, L. Puchkova, M. E. Rebus, G. A. Buryak, S. E. Olkin, A. S. Kozlov, M. R. Kabilov
Summary: Microorganisms in atmospheric aerosols were analyzed in four sites with different anthropogenic load in Novosibirsk. The study found that spore-forming bacteria of the genus Bacillus and cocci of the genera Staphylococcus and Micrococcus were predominant in winter samples, while the concentrations and diversity of different bacteria, actinomycetes, and fungi sharply increased in spring-summer and autumn samples. Furthermore, a significant number of antibiotic-resistant hemolytic spore-forming bacteria and staphylococci with enzymes contributing to the development of infectious processes were identified.
ATMOSPHERIC AND OCEANIC OPTICS
(2022)
Article
Optics
M. Yu Arshinov, V. G. Arshinova, B. D. Belan, D. K. Davydov, G. A. Ivlev, A. S. Kozlov, L. Kuibida, T. M. Rasskazchikova, D. Simonenkov, G. N. Tolmachev, A. Fofonov
Summary: The anomalous vertical distribution of organic aerosol on September 14, 2018, was analyzed based on aircraft sounding data, showing a significant increase in maximal concentration in the boundary layer compared to previous measurements. The contribution of aerosols from different origins to total concentration in different tropospheric layers was estimated, with potential sources identified in boreal forests and industrial infrastructure.
ATMOSPHERIC AND OCEANIC OPTICS
(2021)