Low Prevalence of Gram-Positive Isolates Showing Elevated Lefamulin MIC Results during the SENTRY Surveillance Program for 2015–2016 and Characterization of Resistance Mechanisms

In Vitro Activity of Lefamulin against Sexually Transmitted Bacterial Pathogens

(2018) Susanne Paukner et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Clonal Emergence of Invasive Multidrug-Resistant Staphylococcus epidermidis Deconvoluted via a Combination of Whole-Genome Sequencing and Microbiome Analyses

(2018) Xiqi Li et al.   CLINICAL INFECTIOUS DISEASES

ZAAPS programme results for 2016: an activity and spectrum analysis of linezolid using clinical isolates from medical centres in 42 countries

(2018) Rodrigo E Mendes et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Lefamulin: Review of a promising novel pleuromutilin antibiotic

(2018) Michael P. Veve et al.   PHARMACOTHERAPY

Mobile lincosamide resistance genes in staphylococci

(2018) Andrea T. Feßler et al.   PLASMID

Identification of a New Antimicrobial Resistance Gene Provides Fresh Insights Into Pleuromutilin Resistance in Brachyspira hyodysenteriae, Aetiological Agent of Swine Dysentery

(2018) Roderick M. Card et al.   Frontiers in Microbiology

Antibiotic Resistance ABC-F Proteins: Bringing Target Protection into the Limelight

(2018) Liam K. R. Sharkey et al.   ACS Infectious Diseases

Cross-resistance to lincosamides, streptogramins A and pleuromutilins in Streptococcus agalactiae isolates from the USA

(2017) Paulina A. Hawkins et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

First outbreak of colonization by linezolid- and glycopeptide-resistant Enterococcus faecium harbouring the cfr gene in a UK nephrology unit

(2017) T. Inkster et al.   JOURNAL OF HOSPITAL INFECTION

Detection and Genetic Environment of Pleuromutilin-Lincosamide-Streptogramin A Resistance Genes in Staphylococci Isolated from Pets

(2017) Fengru Deng et al.   Frontiers in Microbiology

In Vitro Activity of Lefamulin and Other Antimicrobial Agents Against Macrolide-Susceptible and Macrolide-Resistant Mycoplasma pneumoniae from the United States, Europe, and China

(2016) Ken B. Waites et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

In VitroActivity of Lefamulin Tested against Streptococcus pneumoniae with Defined Serotypes, Including Multidrug-Resistant Isolates Causing Lower Respiratory Tract Infections in the United States

(2016) Rodrigo E. Mendes et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

A novel pleuromutilin antibacterial compound, its binding mode and selectivity mechanism

(2016) Zohar Eyal et al.   Scientific Reports

Mutations in the Bacterial Ribosomal Protein L3 and Their Association with Antibiotic Resistance

(2015) Rasmus N. Klitgaard et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Incidence, management and outcomes of the first cfr-mediated linezolid-resistant Staphylococcus epidermidis outbreak in a tertiary referral centre in the Republic of Ireland

(2015) C. O'Connor et al.   JOURNAL OF HOSPITAL INFECTION

Structural insights into species-specific features of the ribosome from the pathogenStaphylococcus aureus

(2015) Zohar Eyal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of ABC transporter genes conferring combined pleuromutilin–lincosamide–streptogramin A resistance in bovine methicillin-resistant Staphylococcus aureus and coagulase-negative staphylococci

(2015) Sarah Wendlandt et al.   VETERINARY MICROBIOLOGY

Characterization ofsal(A), a Novel Gene Responsible for Lincosamide and Streptogramin A Resistance in Staphylococcus sciuri

(2014) Chloé Hot et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Linezolid update: Stable in vitro activity following more than a decade of clinical use and summary of associated resistance mechanisms

(2014) Rodrigo E. Mendes et al.   DRUG RESISTANCE UPDATES

Mutations in the 50S ribosomal subunit of Brachyspira hyodysenteriae associated with altered minimum inhibitory concentrations of pleuromutilins

(2014) Sonja Hillen et al.   VETERINARY MICROBIOLOGY

Detection and new genetic environment of the pleuromutilin-lincosamide-streptogramin A resistance gene lsa(E) in methicillin-resistant Staphylococcus aureus of swine origin

(2013) B. Li et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Antimicrobial activity of the novel pleuromutilin antibiotic BC-3781 against organisms responsible for community-acquired respiratory tract infections (CARTIs)

(2012) H. S. Sader et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

SPAdes: A New Genome Assembly Algorithm and Its Applications to Single-Cell Sequencing

(2012) Anton Bankevich et al.   JOURNAL OF COMPUTATIONAL BIOLOGY

New Transposon Tn6133in Methicillin-Resistant Staphylococcus aureus ST398 Containsvga(E), a Novel Streptogramin A, Pleuromutilin, and Lincosamide Resistance Gene

(2011) Sybille Schwendener et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Resistance to Linezolid Caused by Modifications at Its Binding Site on the Ribosome

(2011) Katherine S. Long et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Plasmid-borne vga(A)-encoding gene in methicillin-resistant Staphylococcus aureus ST398 recovered from swine and a swine farmer in the United States

(2011) Rodrigo E. Mendes et al.   DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE

Detection of the novel vga(E) gene in methicillin-resistant Staphylococcus aureus CC398 isolates from cattle and poultry

(2011) T. Hauschild et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Clinical Outbreak of Linezolid-Resistant Staphylococcus aureus in an Intensive Care Unit

(2010) Miguel Sánchez García   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Small plasmids carrying vga(A) or vga(C) genes mediate resistance to lincosamides, pleuromutilins and streptogramin A antibiotics in methicillin-resistant Staphylococcus aureus ST398 from swine

(2010) K. Kadlec et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Novel Ribosomal Mutations in Staphylococcus aureus Strains Identified through Selection with the Oxazolidinones Linezolid and Torezolid (TR-700)

(2009) J. B. Locke et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Mutations in Ribosomal Protein L3 Are Associated with Oxazolidinone Resistance in Staphylococci of Clinical Origin

(2009) J. B. Locke et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Single 23S rRNA mutations at the ribosomal peptidyl transferase centre confer resistance to valnemulin and other antibiotics inMycobacterium smegmatisby perturbation of the drug binding pocket

(2009) Katherine S. Long et al.   MOLECULAR MICROBIOLOGY

Linezolid and Tiamulin Cross-Resistance in Staphylococcus aureus Mediated by Point Mutations in the Peptidyl Transferase Center

(2008) K. Miller et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY