Article
Clinical Neurology
Nisha Gadgil, Guillermo Aldave, William E. Whitehead, Adam A. Dmytriw, Karen Chen, Darren Orbach, Ilko Maier, Daniel Behme, Kyle M. Fargen, Lucas Elijovich, David Dornbos, Alejandro Spiotta, Peter Kan
Summary: This study suggests that endovascular treatment may be a safe and effective option for pediatric patients with CVST who do not respond to systemic anticoagulation. Most patients had favorable outcomes at 90 days postprocedure.
PEDIATRIC NEUROLOGY
(2021)
Article
Gastroenterology & Hepatology
Ji Hoon Yu, Jeong Woo Lee, Jun-young Seo, Ju Sang Park, Sang Jong Park, Sang-Jung Kim, Eun Jeong Jang, Sang Woon Park, Jae Woo Yeon
Summary: This study retrospectively investigated the records of 156 patients treated with transarterial visceral embolization (TAE) and found that thrombocytopenia and larger ulcer size were risk factors for rebleeding after TAE. The AIMS65 score was a significant predictor of rebleeding after TAE.
SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY
(2023)
Review
Oncology
Yiqing Mao, Jiarong Lan
Summary: The geriatric nutritional risk index (GNRI) can serve as a valuable indicator for predicting the prognosis of colorectal cancer (CRC) patients undergoing surgery. Patients with low GNRI have poor overall and disease-free survival, as well as a higher risk of complications.
FRONTIERS IN ONCOLOGY
(2022)
Article
Clinical Neurology
Weizhi Qiu, Chubin Liu, Jinfu Ye, Gang Wang, Fuxing Yang, Zhigang Pan, Weipeng Hu, Hongzhi Gao
Summary: This study found that the age-to-initial GCS score ratio (AGR) is closely associated with the risk of gastrointestinal bleeding (GIB) in patients with primary intracerebral hemorrhage (ICH). A higher AGR can be used as an independent predictor for GIB following ICH.
FRONTIERS IN NEUROLOGY
(2023)
Article
Surgery
Lois G. Kim, Michael J. Sweeting, David Epstein, Maarit Venermo, Fiona E. Rohlffs, Roger M. Greenhalgh
Summary: Compared with the outcomes of the EVAR-1 trial, adherence to the EVAR-1 scan protocol in simulation models reduced AAA deaths and increased elective re-interventions. The European Society re-intervention guidelines provided the most clinically effective strategy, but with an increase in re-intervention rates. Annual ultrasound in primary care was the cheapest and most cost-effective strategy that reduced AAA-related deaths.
Review
Cardiac & Cardiovascular Systems
Mattia Galli, Renzo Laborante, Felicita Andreotti, Rocco Vergallo, Rocco Antonio Montone, Antonio Iaconelli, Carlo Trani, Francesco Burzotta, Filippo Crea, Domenico D'Amario
Summary: Percutaneous coronary intervention (PCI) is a relatively safe procedure, but is inevitably associated with short and mid-to-long term increased bleeding risk. Bleeding is an important prognostic factor and it is important to study strategies for reducing bleeding.
REVIEWS IN CARDIOVASCULAR MEDICINE
(2022)
Review
Clinical Neurology
Ahmad M. Tarawneh, Dritan Pasku, Nasir A. Quraishi
Summary: This study reviewed the incidence of complications and unplanned re-operations after surgery for metastatic spinal tumors, with surgical site infection being the main complication and a high re-operation rate observed.
EUROPEAN SPINE JOURNAL
(2021)
Article
Cardiac & Cardiovascular Systems
Kun Na, Miaohan Qiu, Ningxin Wei, Jiayin Li, Chenghui Yan, Jing Li, Yi Li, Yaling Han
Summary: This study investigated the feasibility of identifying high-risk acute coronary syndrome (ACS) patients who underwent percutaneous coronary intervention (PCI) and were at risk of both ischemia and bleeding (bi-risk) using the OPT-BIRISK criteria. The findings suggest that extended dual antiplatelet therapy (DAPT) may lower the risk of stroke without significantly increasing the risk of serious bleeding in bi-risk patients who remained event-free after a year of DAPT.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2023)
Article
Dentistry, Oral Surgery & Medicine
Ori Finfter, Refael Cohen, Aiham Hanut, Lilach Gavish, Yehuda Zadik
Summary: This study aimed to evaluate the efficacy of high-power laser photobiomodulation therapy for immediate pain relief in refractory oral mucositis patients. The results showed that 94% of patients experienced immediate pain reduction following the photobiomodulation therapy, with 61% experiencing a reduction of over 50% and 35% reporting complete elimination of initial pain. The analgesic benefit of the therapy lasted for an average of 6.0 +/- 5.1 days.
Article
Pediatrics
Alyssa D. Brown, Michael D. Traynor, D. Dean Potter, Michael B. Ishitani, Christopher R. Moir, Paul J. Galardy, Denise B. Klinkner
Summary: A lack of contemporary data about pediatric gastrointestinal ulcer disease was addressed by a retrospective study from 1990 to 2019, which found that immunosuppressed children were more likely to require surgical intervention for ulcers. The study also showed that immunosuppressed patients have more complications, longer hospital stays, and are more likely to need surgical intervention compared to immunocompetent patients. Immunosuppressed pediatric patients with ulcers may benefit from ulcer prophylaxis and early investigation of epigastric pain.
JOURNAL OF PEDIATRIC SURGERY
(2021)
Article
Clinical Neurology
Urs Fisch, Anja L. Junger, Sira M. Baumann, Saskia Semmlack, Gian Marco De Marchis, Sabina Hunziker, Stephan Ruegg, Stephan Marsch, Raoul Sutter
Summary: This study aimed to investigate the frequency of induced EEG burst suppression pattern during continuous IV anesthesia (IVAD) and its associated outcomes in adult patients treated for refractory status epilepticus (RSE). It was found that incomplete burst suppression occurred in 14% of patients without cerebral anoxia, while complete burst suppression occurred in 21% of patients. No association was found between burst suppression and outcomes in patients without cerebral anoxia, but in patients with cerebral anoxia, induced burst suppression was associated with persistent seizure termination and higher survival rate.
Article
Gastroenterology & Hepatology
Armin Kuellmer, Tobias Mangold, Dominik Bettinger, Lars Maruschke, Andreas Wannhoff, Karel Caca, Edris Wedi, Ali Seif Amir Hosseini, Tobias Kleemann, Thomas Schulz, Carlo Jung, Robert Thimme, Arthur Schmidt
Summary: OTSC treatment is superior to TAE treatment in refractory peptic ulcer bleeding, with lower ICU stay and in-hospital mortality rates.
UNITED EUROPEAN GASTROENTEROLOGY JOURNAL
(2021)
Article
Multidisciplinary Sciences
Dong Gyu Kim, Kwangsoon Kim, Ji-Eun Lee, Joon Ho, Jin Kyong Kim, Sang-Wook Kang, Jandee Lee, Jong Ju Jeong, Kee-Hyun Nam, Woong Youn Chung
Summary: This study investigated the feasibility of using a robotic system for re-do operation in locoregional recurrent thyroid cancer. The results showed that re-do robotic operation can be a feasible alternative with similar oncologic outcomes and superior cosmetic satisfaction.
SCIENTIFIC REPORTS
(2022)
Article
Medicine, General & Internal
Cristiano Spadaccio, David Rose, Antonio Nenna, Rebecca Taylor, Mohamad Nidal Bittar
Summary: In patients undergoing coronary artery bypass grafting (CABG), conservative management may be a safe and viable option for hemodynamically stable patients experiencing significant but non-critical bleeding. It may have advantages in terms of reducing postoperative morbidities and hospital stay.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Gastroenterology & Hepatology
Haijun Mou, Cheng Zou, Guoqing Shi, Sheng Wu, Rui Xie, Xuemei Liu, Jie Yang, Biguang Tuo
Summary: This study evaluated the efficacy and safety of endoscopic cyanoacrylate injection therapy for refractory high-risk peptic ulcer bleeding. The results showed that this therapy had a high successful hemostasis rate in conventional endoscopic therapy.
SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY
(2023)
Article
Surgery
Gisli Gunnar Jonsson, Niklas Marklund, Kaj Blennow, Henrik Zetterberg, Anders Wanhainen, David Lindstrom, Jacob Eriksson, Kevin Mani
Summary: This prospective observational study on patients undergoing cEVAR surgery showed an increase in CSF biomarkers post-surgery, indicating a potential method for detecting impending SCI. However, due to the small sample size and low event rate, specific correlation between elevated spinal fluid biomarkers and clinical symptoms of SCI was not established.
ANNALS OF VASCULAR SURGERY
(2022)
Article
Surgery
Karl Sorelius, Anders Wanhainen, Mia Furebring, Kevin Mani, T. Resch, R. Hultgren, C. M. Wahlgren, H. Roos, A. Ojersjo, D. Lindstrom, R. Vaccarino, B. Arvidsson, L. Bilos, A. Pirouzram, C. Arnerlov, G. Simo, M. Svensson, J. Magnusson, H. Astrand, M. Palm, M. Holsti, S. Mellander, D. Korman, K. Djavani-Gidlund, M. Huss, A. Bertszel, M. Docter, C. Drott, O. Nelzen, T. Wetterling, M. Chu, N-P Gilgen, P. Gillgren
Summary: This study aimed to examine the microbiological findings of surgically treated infective native aortic aneurysms (INAAs) in Sweden. The results showed that Staphylococcus aureus, Streptococcus species, and Salmonella species accounted for 50% of the identified pathogens. The study also found a 20% incidence of infection-related complications (IRCs), which were associated with high mortality.
ANNALS OF VASCULAR SURGERY
(2022)
Article
Surgery
Anne Burdess, Mario D'Oria, Kevin Mani, Gustaf Tegler, David Lindstrom, John Mogensen, Tilo Koelbel, Anders Wanhainen
Summary: The use of a novel, investigational, dissection-specific stent-graft (DSSG) for the treatment of chronic type B aortic dissection (CTBAD) with TEVAR is safe and feasible. The early real-world experience shows promising mid-term outcomes with low rates of distal stent-graft-induced new entry tears (dSINE) or unplanned re-interventions, and satisfactory aortic remodeling during follow-up. Longer follow-up is needed to draw firm conclusions.
ANNALS OF VASCULAR SURGERY
(2022)
Article
Surgery
Mario D'Oria, Jacob Budtz-Lilly, David Lindstrom, Goran Lundberg, Magnus Jonsson, Anders Wanhainen, Kevin Mani, Jon Unosson
Summary: The study showed that F-BEVAR is equally safe and feasible for patients with prior infrarenal repair compared to those without, but the former group had higher rates of TV-related endoleaks, leading to lower freedom from aneurysm sac shrinkage during follow-up.
JOURNAL OF ENDOVASCULAR THERAPY
(2022)
Review
Surgery
Carlota Fernandez Prendes, David Lindstrom, Kevin Mani, Gustaf Tegler, Anders Wanhainen
Summary: This study summarized the literature on in situ laser fenestration (ISLF), including experimental and clinical studies. Experimental studies suggested that the use of multifilament polyethylene terephthalate and noncompliant balloons for dilation is a durable technique for ISLF. Clinical studies showed promising short-term outcomes in arch and visceral vessel revascularization, with low rates of in-hospital mortality, stroke, and end-organ ischemia. However, the long-term durability of ISLF has not yet been determined, and it should be used with caution in selected symptomatic and urgent cases.
JOURNAL OF VASCULAR SURGERY
(2022)
Article
Surgery
Mario D'Oria, Anders Wanhainen, Kevin Mani, David Lindstrom
Summary: This study aimed to evaluate the frequency and type of adverse events that can occur during the waiting period for complex aortic endovascular repair. The study found that a substantial proportion of patients may experience adverse events, either related to aneurysm rupture or underlying comorbidities, during the waiting period. Efforts to decrease this risk could significantly improve outcomes.
JOURNAL OF VASCULAR SURGERY
(2022)
Article
Pathology
Whayoung Lee, Timothy Law, Yunxia Lu, Thomas K. Lee, Julio A. Ibarra
Summary: Mitotic rate is a key prognostic factor in invasive breast carcinoma, and the proposed 1 HPF method shows similar concordance and interobserver agreement as the conventional method, showing superior correlation in the score 1 group.
Article
Surgery
Ross Naylor, Barbara Rantner, Stefano Ancetti, Gert J. de Borst, Marco De Carlo, Alison Halliday, Stavros K. Kakkos, Hugh S. Markus, Dominick J. H. McCabe, Henrik Sillesen, Jos C. van den Berg, Melina Vega de Ceniga, Maarit A. Venermo, Frank E. G. Vermassen
EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY
(2023)
Editorial Material
Gastroenterology & Hepatology
Yunxia Lu
Review
Health Care Sciences & Services
Andrea Xodo, Mario D'Oria, Bernardo Mendes, Luca Bertoglio, Kevin Mani, Mauro Gargiulo, Jacob Budtz-Lilly, Michele Antonello, Gian Franco Veraldi, Fabio Pilon, Domenico Milite, Cristiano Calvagna, Filippo Griselli, Jacopo Taglialavoro, Silvia Bassini, Anders Wanhainen, David Lindstrom, Enrico Gallitto, Luca Mezzetto, Davide Mastrorilli, Sandro Lepidi, Randall DeMartino
Summary: The development and application of complex endovascular techniques have revolutionized the field of vascular surgery, especially in the treatment of juxtarenal abdominal aortic aneurysm, pararenal abdominal aortic aneurysm, or thoracoabdominal aortic aneurysm. It is crucial to prevent and manage complications before and after surgery to improve clinical outcomes.
JOURNAL OF PERSONALIZED MEDICINE
(2022)
Article
Surgery
Matthew Joe Grima, Anders Wanhainen, David Lindstrom
Summary: This study evaluated the application of in situ laser fenestration (ISLF) in common aortic endografts and bridging stent-grafts. The results showed that Dacron endografts responded well to the ISLF technology, and optimal deployment of the bridging stents was achieved after inflation and/or flaring with high-pressure balloons. Further research with different commercially-available bridging stent-grafts and endografts is recommended to assess the durability of in situ fenestration (ISF) and bridging stents in ISF.
JOURNAL OF ENDOVASCULAR THERAPY
(2022)
Article
Surgery
Gianmarco Zuccon, Anders Wanhainen, David Lindstrom, Gustaf Tegler, Matthew Joe Grima, Kevin Mani
Summary: This study evaluated the outcomes of fenestrated endovascular aortic repair procedures at Uppsala university hospital using a simplified bare-wire Target vessel (SMART) technique. The results showed that the SMART technique is a safe alternative to standard FEVARs with excellent technical results and acceptable target vessel patency in the mid-term, while reducing the risk for introducer-induced lower limb ischemia, complications, and morbidity.
JOURNAL OF ENDOVASCULAR THERAPY
(2022)
Article
Surgery
Anastasia Dean, Anders Wanhainen, Kevin Mani, Marek Kuzniar, Matthew Grima, Gianmarco Zuccon, David Lindstrom
Summary: This study examined the use of in situ laser fenestration (ISLF) in the treatment of emergent aortic pathology. The results showed that ISLF is a promising new technique that can achieve excellent technical outcomes in experienced aortic centers, even during the learning curve. It is a feasible option for complex aortic pathology in the acute setting when open surgery is not feasible.
ANNALS OF VASCULAR SURGERY
(2023)
Article
Public, Environmental & Occupational Health
Bingya Ma, Yunxia Lu
Summary: This retrospective study found that gastrointestinal cancer patients belonging to racial minorities have a higher risk of COVID-19-related hospitalization or emergency room visits compared to white patients. However, no significant racial disparities were found in 30-day all-cause mortality and mechanical ventilation rate. Vaccination status is a crucial factor associated with the prognosis of gastrointestinal cancer patients among different race/ethnicity groups.
JOURNAL OF RACIAL AND ETHNIC HEALTH DISPARITIES
(2023)
Article
Surgery
Gisli Gunnar Jonsson, Maysam Shehab, Anders Wanhainen, Kevin Mani, Marek Kuzniar, David Lindstrom
Summary: The aim of this study was to develop an optimized design of an endograft suitable for over 90% of juxtarenal and pararenal abdominal aortic aneurysms.
JOURNAL OF ENDOVASCULAR THERAPY
(2023)