SCN1A gain of function in early infantile encephalopathy

Dynamic action potential clamp predicts functional separation in mild familial and severe de novo forms ofSCN2Aepilepsy

(2018) Géza Berecki et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Not all SCN1A epileptic encephalopathies are Dravet syndrome

(2017) Lynette G. Sadleir et al.   NEUROLOGY

Voltage-gated sodium channels assemble and gate as dimers

(2017) Jérôme Clatot et al.   Nature Communications

The complete structure of an activated open sodium channel

(2017) Altin Sula et al.   Nature Communications

Dravet Syndrome: Diagnosis and Long-Term Course

(2016) Mary B. Connolly   CANADIAN JOURNAL OF NEUROLOGICAL SCIENCES

BluePyOpt: Leveraging Open Source Software and Cloud Infrastructure to Optimise Model Parameters in Neuroscience

(2016) Werner Van Geit et al.   Frontiers in Neuroinformatics

Reconstruction and Simulation of Neocortical Microcircuitry

(2015) Henry Markram et al.   CELL

Microcircuits and their interactions in epilepsy: is the focus out of focus?

(2015) Jeanne T Paz et al.   NATURE NEUROSCIENCE

The neocortical microcircuit collaboration portal: a resource for rat somatosensory cortex

(2015) Srikanth Ramaswamy et al.   Frontiers in Neural Circuits

Genetic determinants of common epilepsies: a meta-analysis of genome-wide association studies

(2014)   LANCET NEUROLOGY

On the mechanisms underlying the depolarization block in the spiking dynamics of CA1 pyramidal neurons

(2012) Daniela Bianchi et al.   JOURNAL OF COMPUTATIONAL NEUROSCIENCE

Fast spiking interneuron control of seizure propagation in a cortical slice model of focal epilepsy

(2012) Mario Cammarota et al.   JOURNAL OF PHYSIOLOGY-LONDON

Autistic-like behaviour in Scn1a +/− mice and rescue by enhanced GABA-mediated neurotransmission

(2012) Sung Han et al.   NATURE

Specific deletion of NaV1.1 sodium channels in inhibitory interneurons causes seizures and premature death in a mouse model of Dravet syndrome

(2012) C. S. Cheah et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Insights into pathophysiology and therapy from a mouse model of Dravet syndrome

(2011) John C. Oakley et al.   EPILEPSIA

Genotype-phenotype associations in SCN1A-related epilepsies

(2011) S. M. Zuberi et al.   NEUROLOGY

Effective Stimuli for Constructing Reliable Neuron Models

(2011) Shaul Druckmann et al.   PLoS Computational Biology

Three groups of interneurons account for nearly 100% of neocortical GABAergic neurons

(2010) Bernardo Rudy et al.   Developmental Neurobiology

NaV1.1 channels and epilepsy

(2010) William A. Catterall et al.   JOURNAL OF PHYSIOLOGY-LONDON

Prediction by Modeling That Epilepsy May Be Caused by Very Small Functional Changes in Ion Channels

(2009) Evan A. Thomas et al.   ARCHIVES OF NEUROLOGY

Cell-Type-Dependent Molecular Composition of the Axon Initial Segment

(2009) A. Lorincz et al.   JOURNAL OF NEUROSCIENCE

NEURON and Python

(2009) Michael Hines   Frontiers in Neuroinformatics

How do mutant Nav1.1 sodium channels cause epilepsy?

(2008) David S. Ragsdale   BRAIN RESEARCH REVIEWS