Journal
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
Volume 58, Issue 20, Pages 6545-6548Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/anie.201901848
Keywords
allenes; asymmetric synthesis; chirality transfer; cross-coupling; palladium
Categories
Funding
- Deutsche Forschungsgemeinschaft (DFG)
Ask authors/readers for more resources
An enantiospecific palladium-catalyzed decarboxylative coupling of acyclic ,-alkynoic acids with various aryl iodides to chiral tetrasubstituted allenes is described. The coupling reaction comprises a decarboxylative -palladation of ,-disubstituted carboxylic acids to provide the tetrasubstituted allenes with complete point-to-axial chirality transfer in excellent yields.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
