Article
Chemistry, Analytical
A. Muthurasu, V. Ganesh
Summary: Nitrogen-doped carbon dots prepared with Rhodamine B as a donor molecule showed emission color tuning from blue to red, utilized for ratiometric sensing of mercury ion. The photoluminescence properties of N-CDs were effectively quenched by Hg2+ ions, leading to the development of a cheap and selective sensing matrix for the detection of toxic metal ions such as mercury (Hg2+).
ANALYTICAL METHODS
(2021)
Article
Chemistry, Physical
Chuan Huang, Qinbin Zhang, Yichuan Zhang, Mingming Guo
Summary: Nitrogen and phosphorus co-doped carbonized polymer dots (Arg-CPDs) have been synthesized by a facile and rapid microwave heating method using arginine and phosphoric acid as precursors. The Arg-CPDs exhibit bright blue fluorescence in aqueous solution and yellow green phosphorescence in solid state, with the phosphorescence visible to the naked eye for about 4 seconds. The phosphorescence lifetime of Arg-CPDs is 149 ms and 667 ms under ambient conditions and low temperature (77 K), respectively, showing typical phosphorescent properties. Potential applications of the Arg-CPDs in information protection and encryption are demonstrated.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2023)
Article
Spectroscopy
Zi-Bo Ma, Yan Zhang, Xing-Hui Ren, Xi-Wen He, Wen-You Li, Yu-Kui Zhang
Summary: The study successfully achieved dual-reverse-signal ratiometric fluorescence detection of malachite green using synergistic effect of fluorescence resonance energy transfer (FRET) and inner filter effect (IFE), demonstrating low detection limit, rapid response, and satisfactory recoveries in real water samples, making it a promising method for MG detection.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2022)
Article
Chemistry, Multidisciplinary
Meicheng Lu, Congjie Pan, Xuezhen Qin, Mingxia Wu
Summary: Blue fluorescent silicon nanoparticles (SiNPs) with favorable properties were prepared using a one-step hydrothermal method. A novel ratiometric fluorescence method for Vitamin B2 (VB2) detection was established based on the fluorescence behavior of SiNPs in the presence of VB2. Additionally, a simple paper sensor based on SiNPs enabled visual quantitative analysis of VB2 with the support of color recognition software on a smartphone.
Article
Chemistry, Applied
Lingfei Liu, Minjie Qian, Zhen-quan Yang, Lixia Xiao, Xiaojuan Gong, Qin Hu
Summary: This work presents the development of a facial ratiometric fluorescence nanorpobe (RFP) based on gadolinium and nitrogen co-doped CDs for the visual detection of folic acid (FA). The RFP achieved high sensitivity and selectivity towards FA, and a smartphone-assisted visual sensing platform and a paper-based analytical device were developed. The proposed sensing platform demonstrated promising potential as a portable method for on-site analysis of FA.
Article
Spectroscopy
Xin Li, Liuxi Zhao, Yuhan Wu, Ao Zhou, Xuanfeng Jiang, Yuan Zhan, Zhengguang Sun
Summary: Novel orange fluorescent nitrogen and boron co-doped carbon dots (NB-CDs) were synthesized by one-pot solvothermal method, and were found to possess excellent optical properties and high selectivity for the detection of Ce4+ and Al3+.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2022)
Article
Chemistry, Analytical
Guangming Li, Hang Gao, Ningning Wang, Zhaohui Li, Huangxian Ju
Summary: This study proposed a simple and sensitive method for ratiometric fluorescent detection of nucleic acids by controlling the pH-dependent adsorption of dye-labeled DNA on polymer dots. The method showed promising application in bioanalysis with excellent performance and good extendability.
ANALYTICA CHIMICA ACTA
(2022)
Article
Multidisciplinary Sciences
Xiang Zhang, Yu Gu, Yun Zhang, Guo-Yin Yu, Zhi-Peng Liao, Hui-Fang Wu, Chuan-Guo Shi
Summary: In this study, dual-emissive N-GOQDs fluorescent probes were successfully developed for monitoring intracellular pH. These probes possess bright fluorescence, high stability, and good biocompatibility.
Article
Biochemistry & Molecular Biology
Yutong Li, Xinhui Gu, Jiayin Zhao, Fengna Xi
Summary: In this study, a novel ratiometric fluorescence sensing platform based on carbon dots (CDs) as both luminophores and nanozymes was constructed for the sensitive detection of hydrogen peroxide (H2O2). The CDs with peroxidase-mimicking activity were prepared using a hydrothermal method, and exhibited bright blue fluorescence. The catalytic oxidation of o-phenylenediamine (OPD) by CDs in the presence of H2O2 resulted in the generation of 2,3-diaminophenolazine (DAP), leading to fluorescence resonance energy transfer (FRET) and a ratiometric fluorescence system. The CD nanozymes showed good affinity for both OPD and H2O2 substrates, and a low limit of detection (LOD) of 0.42 μM was achieved for H2O2.
Article
Chemistry, Analytical
Zihan Wang, Li Zhang, Yumin Hao, Wenjuan Dong, Yang Liu, Shengmei Song, Shaomin Shuang, Chuan Dong, Xiaojuan Gong
Summary: This study successfully synthesized nitrogen, phosphorus, and chlorine co-doped carbon quantum dots for the preparation of multifunctional and ratiometric fluorescent sensors, which can be used for the sequential determination of riboflavin, Ag+, and Cys with good selectivity and high sensitivity. The sensors were effectively applied for detecting riboflavin, Ag+, and Cys in tablets, river water, and human urine, and showed satisfying results in HeLa cells.
ANALYTICA CHIMICA ACTA
(2021)
Article
Biochemical Research Methods
Huiyan Du, Xia Li, Shuling Xu, Guiguang Cheng, Qingwang Xue, Hongxia Xu
Summary: This study presents a novel FRET ratiometric fluorescence aptasensing strategy for the sensitive and accurate detection of ochratoxin A (OTA) using a nitrogen and sulfur co-doped carbon dot (N/S-CD)-based probe. The strategy involves the liberation of complementary DNA (cDNA) upon sensing of target OTA, which triggers a three-chain DNA composite-based entropy-driven DNA circuit amplification. This amplification enhances the detection performance by anchoring CuO probes on a magnetic bead (MB) and generating Cu2+ ions that oxidize o-phenylenediamine (oPD) to produce yellow fluorescence for FRET with the blue fluorescent N/S-CDs. The method achieves a low limit of detection of 0.006 pg/mL of OTA and allows for visual evaluation of OTA via on-site screening.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
Yingying Chen, Ying He, Jinwen Zhao, Jin Zhang, Ruo Yuan, Shihong Chen
Summary: This study developed a novel hydrophobic localized enrichment strategy using beta-cyclodextrin (beta-CD) to improve the sensitivity of electrochemiluminescence (ECL) detection. The biosensor constructed with TDBA-beta-CD-Pt nanocomposite and PDP PNPs achieved highly sensitive detection of ncovNP. This research provides a promising and sensitive ECL platform for ncovNP detection.
ANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Analytical
Xiufen Liao, Congjin Chen, Jielun Yang, Ruxia Zhou, Lulu Si, Quanlong Huang, Zuqiang Huang, Chunqiu Lv
Summary: N-doped carbon dots (N-CDs) were synthesized by hydrothermal treatment of cellobiose and urea, and a novel anti-false-positive mechanism for phosalone identification was achieved. The constructed sensor showed comparable accuracy and precision to the standard gas chromatographic (GC) method, with excellent recovery rates and low relative standard deviations (RSD).
Article
Chemistry, Multidisciplinary
Yuanjin Zhan, Shuangting Yang, Lifen Chen, Yanbo Zeng, Lei Li, Zhenyu Lin, Longhua Guo, Wei Xu
Summary: A ratiometric fluorescence sensor based on FRET strategy was developed for detecting ALP activity and its inhibitor Na3VO4. The sensor showed high FRET efficiency, ratiometric change in fluorescence intensity, and dual-emission self-correction ability, enabling quantitative detection and visual analysis of ALP activity. This biosensor provides a promising alternative for evaluating ALP-related diseases and can also be utilized for assessing Cu2+, PPi, and Na3VO4 levels, as well as screening ALP inhibitors.
ACS SUSTAINABLE CHEMISTRY & ENGINEERING
(2021)
Article
Chemistry, Analytical
Xinying Gong, Yayun Ji, Fanqiang Meng, Yulu Tian, Dongmei Wang, Huan Chen, Zhengjun Gong
Summary: In this work, a dual-emission nitrogen-doped carbon dots/AuNCs nanohybrid was fabricated and used for the sensitive detection of Pb2+. The sensor achieved quantitative analysis of Pb2+ by measuring the change in fluorescence intensities, and showed good selectivity and anti-interference ability in real water samples. Furthermore, a paper-based sensor was developed for the semi-quantitative determination of Pb2+ by visual observation of color transition.
MICROCHEMICAL JOURNAL
(2023)
Article
Chemistry, Analytical
Liping Lin, Xinhong Song, Yiying Chen, Mingcong Rong, Yiru Wang, Li Zhao, Tingting Zhao, Xi Chen
ANALYTICA CHIMICA ACTA
(2015)
Review
Chemistry, Analytical
Liping Lin, Yaxin Luo, Peiyu Tsai, Jiajing Wang, Xi Chen
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2018)
Article
Chemistry, Analytical
Liping Lin, Yuhan Wang, Yanling Xiao, Wei Liu
Article
Chemistry, Analytical
Liping Lin, Yanling Xiao, Yuhan Wang, Yongnian Zeng, Zujin Lin, Xi Chen
Article
Chemistry, Analytical
Liping Lin, Yaxin Luo, Qiushuang Chen, Qingjiao Lai, Qiaoling Zheng
Article
Biochemistry & Molecular Biology
Liping Lin, Luoyao Wan, Huaqin He, Wei Liu
MOLECULAR GENETICS AND GENOMICS
(2020)
Article
Chemistry, Analytical
Liping Lin, Qingjiao Lai, Qiushuang Chen, Qiaoling Zheng, Meng Fang, Xinghao He, Jinying Qin
Summary: Nitrogen-doped carbon quantum dots (N-CQDs) were successfully synthesized via hydrothermal treatment, demonstrating excellent optical properties and high quantum yield. A 'off-on' fluorescence strategy using N-CQDs for the detection of permanganate and l-ascorbic acid was proposed, showing fast, sensitive, and selective detection capabilities, with satisfactory results in real samples.
Article
Chemistry, Multidisciplinary
Liping Lin, Qiaoling Zheng, Qiushuang Chen, Meng Fang, Qingjiao Lai, Xinghao He, Jinying Qin, Zu-jin Lin, Rongguang Lin
Summary: Fluorescent polydopamine nanoparticles (PDA NPs) with excellent optical properties have been synthesized and applied for tartrazine detection.
NEW JOURNAL OF CHEMISTRY
(2022)
Review
Materials Science, Biomaterials
Meng Fang, Liping Lin, Muyue Zheng, Wei Liu, Rongguang Lin
Summary: Functionalized carbon dots (FCDs) are a promising platform for the treatment of bacterial infectious diseases due to their low cytotoxicity, high biocompatibility, and unique antibacterial mechanisms. This review summarizes the available antibacterial mechanisms of FCDs and their application in the treatment of bacterial inflammation, and discusses the advantages and challenges of applying FCDs in practical antimicrobial applications.
JOURNAL OF MATERIALS CHEMISTRY B
(2023)
Article
Chemistry, Multidisciplinary
Liping Lin, Jiajing Wang, Wei Liu, Yaxin Luo, Yanling Xiao, Yuhan Wang