Article
Surgery
M. Valapour, C. J. Lehr, M. A. Skeans, J. M. Smith, E. Miller, R. Goff, J. Foutz, A. K. Israni, J. J. Snyder, B. L. Kasiske
Summary: The number of lung transplants performed is increasing annually with decreasing waitlist mortality, attributed to more candidates listed for transplant and increasing number of donors. Despite these favorable trends, a small percentage of recovered lungs were not transplanted in 2019. Posttransplant survival rates have shown slight gains, but regional heterogeneity still exists.
AMERICAN JOURNAL OF TRANSPLANTATION
(2021)
Editorial Material
Surgery
M. Colvin, J. M. Smith, Y. Ahn, M. A. Skeans, E. Messick, R. Goff, K. Bradbrook, J. Foutz, A. K. Israni, J. J. Snyder, B. L. Kasiske
Summary: This article discusses the challenges faced in the third year of the new adult heart allocation policy in light of the COVID-19 pandemic. It provides data on the number of new listings, adult and pediatric heart transplants performed, and posttransplant mortality rates. While there has been a slight increase in short-term mortality rates, there is a steady downward trend in longer-term mortality.
AMERICAN JOURNAL OF TRANSPLANTATION
(2022)
Article
Surgery
A. K. Israni, D. Zaun, K. Gauntt, C. Schaffhausen, W. McKinney, J. J. Snyder
Summary: SRTR uses data from OPTN to calculate metrics such as donation rate, organ yield, and rate of organs not transplanted. The number of deceased donors and organ transplants increased in 2020 despite the pandemic, with a notable increase in kidney, liver, and heart transplants. The data also suggests an opportunity to increase transplants by reducing the number of discarded organs.
AMERICAN JOURNAL OF TRANSPLANTATION
(2022)
Article
Surgery
A. Hart, K. L. Lentine, J. M. Smith, J. M. Miller, M. A. Skeans, M. Prentice, A. Robinson, J. Foutz, S. E. Booker, A. K. Israni, R. Hirose, J. J. Snyder
Summary: Despite the ongoing increase in kidney transplants and relatively stable number of patients waiting for a transplant, only a quarter of waitlisted patients receive a deceased-donor kidney transplant within five years.
AMERICAN JOURNAL OF TRANSPLANTATION
(2021)
Article
Surgery
M. Colvin, J. M. Smith, Y. Ahn, M. A. Skeans, E. Messick, R. Goff, K. Bradbrook, J. Foutz, A. K. Israni, J. J. Snyder, B. L. Kasiske
Summary: Heart transplant surgeries continued to increase in 2019, with improvements in short-term and long-term mortality rates. Mortality rates decreased for adult recipients, while there was also a decrease in mortality rates for pediatric recipients.
AMERICAN JOURNAL OF TRANSPLANTATION
(2021)
Article
Surgery
S. P. Horslen, J. M. Smith, T. Weaver, M. Cafarella, J. Foutz
Summary: Despite small increases in additions to the intestine transplant waitlist, overall intestine transplant activity has decreased over the last decade. Waitlist mortality has continued to fall for pediatric populations and remain stable for adults. While 1-year graft survival has improved, there is no noticeable improvement in 3- and 5-year graft survival. Immunosuppression practices favor the use of an induction agent followed by tacrolimus-based regimens. Patient survival at 5 years is currently the same for isolated intestines and liver-inclusive allograft recipients.
AMERICAN JOURNAL OF TRANSPLANTATION
(2022)
Article
Surgery
J. A. Hernandez, J. Miller, N. C. Oleck, D. Porras-Fimbres, J. Wainright, K. Laurie, S. E. Booker, G. Testa, A. K. Israni, L. C. Cendales
Summary: The first successful vascularized composite allograft (VCA) transplant was performed in the United States in 1998, and since then, significant progress has been made in the field. While patient demographic data is limited, the overall outcomes have been promising, with the majority of transplants resulting in functioning grafts.
AMERICAN JOURNAL OF TRANSPLANTATION
(2022)
Article
Surgery
A. J. Kwong, N. H. Ebel, W. R. Kim, J. R. Lake, J. M. Smith, D. P. Schladt, M. A. Skeans, J. Foutz, K. Gauntt, M. Cafarella, J. J. Snyder, A. K. Israni, B. L. Kasiske
Summary: The COVID-19 pandemic had a significant impact on transplant programs and outcomes, but the number of liver transplants performed in the United States reached a record high. Living donation activity decreased, but the survival rates for patients with liver transplants continued to improve. The liver transplant waitlists for both adults and children decreased in size, and a new liver distribution policy based on acuity circles was implemented. The predominant indication for liver transplants among adults in 2020 was alcohol-associated liver disease.
AMERICAN JOURNAL OF TRANSPLANTATION
(2022)
Article
Surgery
K. L. Lentine, J. M. Smith, A. Hart, J. Miller, M. A. Skeans, L. Larkin, A. Robinson, K. Gauntt, A. K. Israni, R. Hirose, J. J. Snyder
Summary: The year 2020 presented challenges for kidney transplantation, with a slight decrease in the total number of transplants and a significant decline in living donor transplants due to the COVID-19 pandemic. Racial disparities in living donor transplant access persist. Pediatric kidney transplants were also impacted, with a decrease in the total number of transplants and a continued decrease in deceased donor transplants among pediatric candidates.
AMERICAN JOURNAL OF TRANSPLANTATION
(2022)
Article
Surgery
R. Kandaswamy, P. G. Stock, J. Miller, M. A. Skeans, J. White, J. Wainright, N. T. T. Kyaw, S. Niederhaus, A. K. Israni, J. J. Snyder
Summary: In 2019, there was a slight decrease in the overall number of pancreas transplants, but an increase in simultaneous pancreas-kidney transplants and new waitlist registrations. Waiting time for SPK decreased, while PTA recipient mean waiting time remained higher.
AMERICAN JOURNAL OF TRANSPLANTATION
(2021)
Article
Surgery
R. Kandaswamy, P. G. Stock, J. Miller, M. A. Skeans, J. White, J. Wainright, N. T. T. Kyaw, S. Niederhaus, A. K. Israni, J. J. Snyder
Summary: The number of pancreas transplants and new waitlist registrations decreased in 2020. Waiting times increased for certain types of transplants, but the rates of graft failure and other long-term outcomes showed consistent improvement over the past decade.
AMERICAN JOURNAL OF TRANSPLANTATION
(2022)
Article
Surgery
S. P. Horslen, J. M. Smith, Y. Ahn, M. A. Skeans, M. Cafarella, S. M. Noreen, J. J. Snyder, A. K. Israni
Summary: Intestine transplants are life-saving procedures that have seen a decrease in numbers over the past decade, with little variation in patient survival rates based on graft type in recent years. Early graft loss has increased, particularly in recipients of combined liver and intestine transplants.
AMERICAN JOURNAL OF TRANSPLANTATION
(2021)
Article
Surgery
B. L. Kasiske, K. L. Lentine, Y. Ahn, M. A. Skeans, T. Eberhard, C. Folken, J. Wainright, L. Larkin, C. Nystedt
Summary: Living donor transplantation is an important source of organs, but there has been little growth in the number of living donor transplants in the past decade. To better understand the barriers and risks associated with living donation, a national registry has been established.
AMERICAN JOURNAL OF TRANSPLANTATION
(2022)
Article
Surgery
A. K. Israni, D. Zaun, J. D. Rosendale, C. Schaffhausen, W. McKinney, J. J. Snyder
Summary: In 2019, there was an increase in both the number of deceased organ donors and organ transplants, which may be linked to the rising death rates of young people due to the opioid epidemic. The data indicates an opportunity to increase transplant numbers by reducing organ discards.
AMERICAN JOURNAL OF TRANSPLANTATION
(2021)
Article
Surgery
M. Valapour, C. J. Lehr, M. A. Skeans, J. M. Smith, E. Miller, R. Goff, T. Mupfudze, K. Gauntt, J. J. Snyder
Summary: In 2020, there was a decrease in the number of lung transplants performed and candidates added to the waiting list, along with a decline in lung donors. This can be attributed to the impact of the global COVID-19 pandemic. However, the median time to transplant continued to decrease and posttransplant survival rates remained stable.
AMERICAN JOURNAL OF TRANSPLANTATION
(2022)
