Article
Critical Care Medicine
Tai Pham, Leo Heunks, Giacomo Bellani, Fabiana Madotto, Irene Aragao, Gaetan Beduneau, Ewan C. Goligher, Giacomo Grasselli, Jon Henrik Laake, Jordi Mancebo, Oscar Penuelas, Lise Piquilloud, Antonio Pesenti, Hannah Wunsch, Frank van Haren, Laurent Brochard, John G. Laffey
Summary: This study investigated the management and outcomes of weaning from invasive mechanical ventilation in patients requiring at least 2 days of ventilation. The results showed that only 65% of patients were successfully weaned at 90 days. Factors such as delayed initiation of weaning and excessive sedation levels were associated with weaning failure. Understanding these factors could improve the success rate of weaning.
LANCET RESPIRATORY MEDICINE
(2023)
Article
Pharmacology & Pharmacy
C. Li, J. He, Huifang Yu, L. Zhao, D. Li, Yao Chen, Yun Liu
Summary: Programmed sedation and analgesia combined care for intensive care unit patients with tracheal intubation can significantly improve clinical efficacy, shorten treatment time, reduce the incidence of adverse events, and increase nursing satisfaction.
INDIAN JOURNAL OF PHARMACEUTICAL SCIENCES
(2021)
Article
Computer Science, Artificial Intelligence
Yan Jia, Chaitanya Kaul, Tom Lawton, Roderick Murray-Smith, Ibrahim Habli
Summary: Weaning from mechanical ventilation is crucial in ICU care, as both prolonged dependence on mechanical ventilation and premature extubation increase the risk of complications and healthcare costs. This study developed a decision support model using CNN to predict extubation readiness with 86% accuracy, based on historical ICU data extracted from MIMIC-III.
ARTIFICIAL INTELLIGENCE IN MEDICINE
(2021)
Article
Infectious Diseases
Ali Safavi, Shahram Molavynejad, Mahboobeh Rashidi, Marziyeh Asadizaker, Elham Maraghi
Summary: This study aimed to determine the effect of implementing infection control guidelines on the incidence of ventilator-associated pneumonia (VAP) in patients admitted to the intensive care unit (ICU). The results showed that the implementation of infection control guidelines could significantly reduce the incidence of VAP and its diagnostic indicators.
BMC INFECTIOUS DISEASES
(2023)
Article
Critical Care Medicine
Qiao He, Wen Wang, Shichao Zhu, Mingqi Wang, Yan Kang, Rui Zhang, Kang Zou, Zhiyong Zong, Xin Sun
Summary: Ventilator-associated pneumonia (VAP) is the most common hospital-acquired infection in intensive care units (ICUs), but the adoption of ventilator-associated event (VAE) surveillance outside the USA is limited. A study in China found that VAE was common in ICU patients with >= 4 ventilator days, and all tiers of VAEs were associated with poor clinical outcomes, including longer hospital stays and increased risk of mortality. These findings emphasize the importance of VAE surveillance and the development of new strategies to prevent VAEs.
Article
Health Care Sciences & Services
Matthieu Le Dorze, Romain Barthelemy, Mikhael Giabicani, Gerard Audibert, Francois Cousin, Clement Gakuba, Rene Robert, Benjamin Chousterman, Pierre-Francois Perrigault
Summary: This study investigates the practice of continuous and deep sedation in French ICUs and reveals issues such as non-compliance with decision-making process and excessive medication dosage. It emphasizes the importance of standardizing and improving this practice.
PALLIATIVE MEDICINE
(2023)
Article
Nursing
Niamh Kelly, Bronagh Blackwood, Nicki Credland, Louise Stayt, Christine Causey, Lewis Winning, Daniel F. McAuley, Fionnuala T. Lundy, Ikhlas El Karim
Summary: The study aimed to investigate oral care practices in adult ICUs in the UK and found significant variability in the provision and methods of oral care, as well as a lack of standardization in oral assessments and care plans. It highlights the need for optimal oral care standards and further research to improve oral care for ICU patients.
NURSING IN CRITICAL CARE
(2023)
Article
Management
Christopher Charles Anderson, Jessica L. Johnson, Bennett P. deBoisblanc, Sarah E. Jolley
Summary: The study found that methods used in usual clinical practice to assess sedation frequently led to oversedation. Results suggest that nurse managers should monitor for signs of care erosion and consider using explicit scripts during sedation assessment and/or providing frequent education to ensure accuracy in sedation assessment.
JOURNAL OF NURSING MANAGEMENT
(2021)
Article
Health Care Sciences & Services
Wei-Teing Chen, Hai-Lun Huang, Pi-Shao Ko, Wen Su, Chung-Cheng Kao, Sui-Lung Su
Summary: This study developed an artificial intelligence model that successfully predicted ventilator weaning outcomes in ICU patients using a few easily accessible parameters. The model has important implications for clinical practice.
JOURNAL OF PERSONALIZED MEDICINE
(2022)
Article
Nursing
Selda Celik, Feride Taskin Yilmaz, Gulnaz Altas
Summary: This study aimed to examine the development, characteristics, and risk factors of medical device-related pressure injury (MDRPI) in intensive care units (ICU). The study found that approximately one in four ICU patients developed MDRPI, and the number of medical devices and hospitalization days were important determinant risk factors.
JOURNAL OF CLINICAL NURSING
(2023)
Article
Critical Care Medicine
Daverio Marco, Florian von Borell, Anne-Sylvie Ramelet, Francesca Sperotto, Paula Pokorna, Sebastian Brenner, Maria Cristina Mondardini, Dick Tibboel, Angela Amigoni, Erwin Ista
Summary: This survey explores the current practices of pain and sedation management and monitoring in European pediatric intensive care units (PICUs). The results show significant variations in drug choices, dosing, and assessment strategies. Further research and evidence-based guidelines are needed to optimize drug dosing and improve analgosedation assessment.
Article
Medicine, General & Internal
Dong-gon Hyun, Jee Hwan Ahn, Ha-Yeong Gil, Chung Mo Nam, Choa Yun, Jae-Myeong Lee, Jae Hun Kim, Dong-Hyun Lee, Ki Hoon Kim, Dong Jung Kim, Sang -Min Lee, Ho-Geol Ryu, Suk-Kyung Hong, Jae -Bum Kim, Eun Young Choi, JongHyun Baek, Jeoungmin Kim, Eun Jin Kim, Tae Yun Park, Je Hyeong Kim, Sunghoon Park, Chi-Min Park, Won Jai Jung, Nak-Jun Choi, Hang-Jea Jang, Su Hwan Lee, Young Seok Lee, Gee Young Suh, Woo-Sung Choi, Keu Sung Lee, Hyung Won Kim, Young-Gi Min, Seok Jeong Lee, Chae-Man Lim
Summary: Early deep sedation is highly prevalent in Korean ICUs and is associated with delayed extubation, but not prolonged ICU stay or in-hospital death.
JOURNAL OF KOREAN MEDICAL SCIENCE
(2023)
Article
Medical Informatics
Bertrand Bouvarel, Fabrice Carrat, Nathanael Lapidus
Summary: In this study, predictive models of short-term mortality in the ICU were developed using longitudinal data. Multiple imputation was used to handle missing data, and it was found that this method performed similarly to complete-case analysis while retaining more patient data. The study demonstrated the potential value of automated analysis of electronic health records as a surveillance tool in the ICU.
BMC MEDICAL INFORMATICS AND DECISION MAKING
(2023)
Review
Education & Educational Research
Sorayya Rezayi, Alireza Amanollahi, Leila Shahmoradi, Nafiseh Rezaei, Meysam Rahmani Katigari, Mitra Zolfaghari, Babak Manafi
Summary: This study aimed to evaluate the effect of technology-based educational tools on training critical care nurses and nursing students, finding that these tools significantly improve participants' levels of knowledge, skills, and self-confidence.
BMC MEDICAL EDUCATION
(2022)
Article
Nutrition & Dietetics
Sarah Damanti, Giulia Cristel, Giuseppe Alvise Ramirez, Enrica Paola Bozzolo, Valentina Da Prat, Agnese Gobbi, Clarissa Centurioni, Ettore Di Gaeta, Andrea Del Prete, Maria Grazia Calabro, Maria Rosa Calvi, Giovanni Borghi, Alberto Zangrillo, Francesco De Cobelli, Giovanni Landoni, Moreno Tresoldi
Summary: This study evaluated the predictive role of muscle mass and quality in COVID-19 patients and concluded that preserving muscle mass might aid in the remission of COVID-19.
CLINICAL NUTRITION
(2022)
Article
Otorhinolaryngology
Samuel J. Rubin, Stefanie S. Saunders, Jacob Kuperstock, Dominick Gadaleta, Peter A. Burke, Gregory Grillone, James M. Moses, Jaime P. Murphy, Gerardo Rodriguez, Andrew Salama, Michael P. Platt
AMERICAN JOURNAL OF OTOLARYNGOLOGY
(2020)
Editorial Material
Critical Care Medicine
Randy Dubin, Jason Ackrivo
Article
Critical Care Medicine
Albert Nadjarian, Jessica LeClair, Taylor F. Mahoney, Eric H. Awtry, Jasvinder S. Bhatia, Lisa B. Caruso, Alexis Clay, David Greer, Karan S. Hingorani, L. F. B. Horta, Michel Ibrahim, Michael H. Ieong, Thea James, Matthew H. Kulke, Remington Lim, Robert C. Lowe, James M. Moses, Jaime Murphy, Ala Nozari, Anuj D. Patel, Brent Silver, Arthur C. Theodore, Ryan Shufei Wang, Ellen Weinstein, Stephen A. Wilson, Anna M. Cervantes-Arslanian
Summary: This study retrospectively validated triage guidelines designed based on acute illness and chronic life-limiting conditions in Massachusetts for critically ill patients. Patients with metastatic cancer, congestive heart failure, end-stage renal disease, and neurodegenerative disease had greater than 50% 1-year mortality, while patients with chronic lung disease and cirrhosis had less than 50% 1-year mortality.
CRITICAL CARE MEDICINE
(2021)
Editorial Material
Clinical Neurology
Jason Ackrivo, Andrew Geronimo
Editorial Material
Pharmacology & Pharmacy
Ryan J. Beechinor, Adam Overberg, Caitlin S. Brown, Sarah Cummins, Jason Mordino
AMERICAN JOURNAL OF HEALTH-SYSTEM PHARMACY
(2022)
Article
Pharmacology & Pharmacy
Ryan J. Beechinor, Ifeoma Mary Eche, Nicholas Edmonds, Jason Mordino, Hope Serafin, Lauren Roller, Tasleem Spracklin, Genevieve Hayes, Aaron Hamby, Krutika N. Mediwala, Drew L. Armstrong, Maegan L. Rogers, Mark A. Baje, Helen S. Lee, Kelly C. Lee, Marcie Lepkowsky, Fanny Li, Mandy Morris, Rita Jue Quan, Christopher Yamamoto, Kirsten H. Ohler, Mike D. Kraft, Kate Starosta, Tricia Parker, Patricia Poole
Summary: This study examined the perceptions of residency candidates, residency practitioners, and residency program directors regarding the virtual interview process for pharmacy residency programs across multiple institutions. The results showed that virtual interviews offered logistical and financial benefits. Most RPDs were in favor of using virtual interviews to replace in-person interviews, while residency candidates and practitioners preferred on-site interviews. Although virtual interviews were easier logistically, the lack of in-person interactions was a common concern for many stakeholders.
AMERICAN JOURNAL OF HEALTH-SYSTEM PHARMACY
(2022)
Editorial Material
Pharmacology & Pharmacy
David M. Hughes, Jason Mordino
Summary: This article responds to a statement by the American Medical Association, pointing out that the association has underestimated and misrepresents the role of pharmacists in clinical practice. Pharmacists play a crucial role in vaccination efforts and treatment plans, and health systems have shown their ability to meet the increased demand for COVID-19 therapies.
JOURNAL OF THE AMERICAN PHARMACISTS ASSOCIATION
(2022)
Article
Cardiac & Cardiovascular Systems
Erin A. Bohula, David D. Berg, Mathew S. Lopes, Jean M. Connors, Ijlal Babar, Christopher F. Barnett, Sunit-Preet Chaudhry, Amit Chopra, Wilson Ginete, Michael H. Ieong, Jason N. Katz, Edy Y. Kim, Julia F. Kuder, Emilio Mazza, Dalton McLean, Jarrod M. Mosier, Ari Moskowitz, Sabina A. Murphy, Michelle L. O'Donoghue, Jeong-Gun Park, Rajnish Prasad, Christian T. Ruff, Mohamad N. Shahrour, Shashank S. Sinha, Stephen D. Wiviott, Sean Van Diepen, Mark Zainea, Vivian Baird-Zars, Marc S. Sabatine, David A. Morrow
Summary: The study evaluated the efficacy and safety of prophylactic full-dose anticoagulation and antiplatelet therapy in critically ill COVID-19 patients. The results showed that full-dose anticoagulation can reduce the risk of thrombotic complications, but increases the risk of bleeding.
Review
Clinical Neurology
Jason Ackrivo
Summary: Adults with ALS have been using home mechanical ventilation for over 50 years, but there are gaps in care due to lack of formal training and poor financial incentives. Initiation of noninvasive ventilation and subsequent adjustments are controversial and there are few guidelines. The advancement of respiratory care in ALS is hindered by critical gaps in pulmonologist availability, training, financial support, clinical research, and ventilation management.
Letter
Clinical Neurology
Jason Ackrivo
Article
Health Care Sciences & Services
Stephanie Grana Van Decker, Nicholas Bosch, Jaime Murphy
Summary: By implementing a series of nursing measures, BMC successfully reduced CAUTI rates and indwelling foley catheter usage, including processes for catheter insertion and maintenance, indications for catheter placement, CAUTI testing, alternatives to indwelling devices, and sterilisation techniques.
Review
Respiratory System
Jason Ackrivo, Lauren Elman, John Hansen-Flaschen
Summary: The recent introduction of remote ventilator telemonitoring has the potential to significantly impact home-assisted ventilation care by allowing for early data review, optimization of settings, and troubleshooting. While remote monitoring may reduce costs associated with emergency room visits and hospitalizations, there are barriers to widespread implementation in countries like the United States.
ANNALS OF THE AMERICAN THORACIC SOCIETY
(2021)
Article
Pharmacology & Pharmacy
Andrew J. Webb, Danielle Margetak, Garrett E. Schramm, Jason Mordino
Summary: Twitter has become a powerful networking and educational tool in the healthcare community, providing access to a vast pool of medical professionals and the opportunity for knowledge sharing. Implementing a successful Twitter account for pharmacy residency programs can create an official voice and brand, while also allowing for dynamic engagement with prospective candidates, current residents, and preceptors. Barriers to successful social media implementation may include gaining buy-in from leadership, creating a social media team, and maintaining engagement momentum.
JOURNAL OF THE AMERICAN COLLEGE OF CLINICAL PHARMACY
(2021)
Article
Respiratory System
Jason Ackrivo, Jesse Y. Hsu, John Hansen-Flaschen, Lauren Elman, Steven M. Kawut
Summary: This study showed that the use of NIV was associated with better survival rates in ALS patients, especially in those with limb-onset ALS. Increasing daily NIV usage was linked to longer survival.
ANNALS OF THE AMERICAN THORACIC SOCIETY
(2021)
Article
Respiratory System
Nicholas A. Bosch, Erika L. Crable, Kimberly A. Ackerbauer, Kristopher Clark, Mari-Lynn Drainoni, Valerie Grim, Michael H. Ieong, Allan J. Walkey, Jaime Murphy
Summary: Clinicians found that the phenobarbital-based pathway was more efficient and simpler to use compared to benzodiazepine-based pathway for treating severe AWS. Patient mechanical ventilation rates were noninferior after implementation of the phenobarbital-based pathway, with decreased physical restraint use and shorter hospital length of stay.
ANNALS OF THE AMERICAN THORACIC SOCIETY
(2021)
