Review
Medicine, General & Internal
Gisele Silvestre Belber, Raissa Ottes Vasconcelos, Heloise Lima Fernandes Agreli, Ana Estela Haddad, Marina Peduzzi, Valeria Marli Leonello
Summary: This study aims to identify the characteristics and applications of telehealth services related to the interprofessional collaborative practice of primary healthcare professionals. A scoping review will be conducted using the Joanna Briggs Institute methodology.
Article
Medicine, General & Internal
Sarah Nouri, Courtney R. Lyles, Elizabeth B. Sherwin, Magdalene Kuznia, Anna D. Rubinsky, Kathryn E. Kemper, Oanh K. Nguyen, Urmimala Sarkar, Dean Schillinger, Elaine C. Khoong
Summary: This study evaluated the changes over time in visits and between-visit interactions among patients with diabetes receiving primary care at two health care systems. The results showed an increase in total encounters during the hybrid-PHE period, driven by growth in between-visit interactions. Differential utilization based on patient characteristics was observed, indicating potential disparities in care.
Article
Clinical Neurology
Charuta Joshi, Mona Jacobson, Lori Silveira, Stephanie Shea, Michele Yang, Krista Eschbach
Summary: Comparison between telemedicine visits during COVID-19 in 2020 and conventional visits in 2019 showed that the overall rate of ED visits or hospital admissions within eight weeks after a neurology visit was less than 5% in 2020. Despite patients reporting worse symptoms during telemedicine visits in 2020, the odds of ED or hospital admission were lower compared to 2019, with patients who called after the telemedicine visit being more likely to require ED visits or hospitalization.
PEDIATRIC NEUROLOGY
(2021)
Article
Urology & Nephrology
Sebastiaan Lambooy, Rathika Krishnasamy, Andrea Pollock, Gerald Hilder, Nicholas A. Gray
Summary: This study evaluated the feasibility and clinical outcomes of telehealth videoconferencing for kidney transplant recipients and chronic kidney disease patients. The research found that TVC uptake was high in the first year but significantly reduced in the second year. There were no significant differences in creatinine and blood pressure between the TVC group and the control group, with high patient satisfaction reported in both groups.
KIDNEY INTERNATIONAL REPORTS
(2021)
Review
Biochemistry & Molecular Biology
Anastasia Poznyak, Nikolay K. Sadykhov, Andrey G. Kartuesov, Evgeny E. Borisov, Vasily N. Sukhorukov, Alexander N. Orekhov
Summary: Atherosclerosis is the leading cause of cardiovascular disease worldwide, and it shares several risk factors with chronic kidney disease. Patients with chronic kidney disease are more susceptible to cardiovascular problems.
Review
Health Care Sciences & Services
Domenico Pascucci, Michele Sassano, Mario Cesare Nurchis, Michela Cicconi, Anna Acampora, Daejun Park, Carmen Morano, Gianfranco Damiani
Summary: This study assessed the impact of IPC interventions on chronic patients compared to usual care and found positive effects on various outcomes, emphasizing the importance of linking interprofessional education with interprofessional collaboration for patient health and wellbeing.
Article
Urology & Nephrology
Sehoon Park, Semin Cho, Soojin Lee, Yaerim Kim, Sanghyun Park, Hyeok Huh, Yong Chul Kim, Seung Seok Han, Hajeong Lee, Jung Pyo Lee, Kwon Wook Joo, Chun Soo Lim, Yon Su Kim, Kyungdo Han, Dong Ki Kim
Summary: Higher visit-to-visit blood pressure variability is significantly associated with a higher risk of dementia in chronic kidney disease patients, regardless of whether it is systolic or diastolic blood pressure variability.
CLINICAL KIDNEY JOURNAL
(2022)
Article
Health Care Sciences & Services
Nicholas M. Mohr, J. Priyanka Vakkalanka, Andrea Holcombe, Knute D. Carter, Kimberly D. McCoy, Heidi M. Clark, Jeydith Gutierrez, Kimberly A. S. Merchant, George J. Bailey, Marcia M. Ward
Summary: This study found that the use of home telehealth (HT) monitoring was associated with an increased risk of emergency department (ED) visits in patients with CHF, COPD, or DM. It also found that patients with COPD had higher rates of hospitalization and all-cause mortality, while patients with CHF or DM had lower all-cause mortality.
JOURNAL OF GENERAL INTERNAL MEDICINE
(2023)
Review
Biology
Jean-Louis Pepin, Bruno Degano, Renaud Tamisier, Damien Viglino
Summary: The progression of chronic obstructive pulmonary disease is often accompanied by acute exacerbations, which can lead to worsened symptoms, declining respiratory function, and reduced quality of life. Predicting and detecting exacerbations early is crucial for effective management. Remote telemonitoring plays a significant role in predicting and managing acute exacerbations in COPD patients.
Article
Pharmacology & Pharmacy
Rachel Stulock, James Montgomery, Marcie Parker, Amanda Singrey, Elizabeth Zeleznikar
Summary: This study describes the role of pharmacists and the initial outcomes of a remote monitoring and telemanagement program implemented during the COVID-19 pandemic. Pharmacists conducted telephone outreach, answered medication questions, and addressed worsening chronic conditions. Their involvement improved population health management and reduced primary care providers' workload during the pandemic.
AMERICAN JOURNAL OF HEALTH-SYSTEM PHARMACY
(2022)
Article
Urology & Nephrology
Anand Srivastava, Xuan Cai, Rupal Mehta, Jungwha Lee, David Chu, Katherine T. Mills, Tariq Shafi, Jonathan J. Taliercio, Jesse Y. Hsu, Sarah J. Schrauben, Milda R. Saunders, Clarissa J. Diamantidis, Chi-yuan Hsu, Sushrut S. Waikar, James P. Lash, Tamara Isakova
Summary: This study identified three distinct subgroups of CKD patients based on cumulative hospitalization trajectories over 4 years, with high-utilizers showing a higher risk for adverse outcomes including ESKD and ESKD-censored death compared to low-utilizers. Trajectories of hospital utilization can help identify CKD patients at high risk for poor clinical outcomes.
KIDNEY INTERNATIONAL REPORTS
(2021)
Review
Public, Environmental & Occupational Health
Steven Yu, Rongjun Wan, Lu Bai, Bingrong Zhao, Qiaoling Jiang, Juan Jiang, Yuanyuan Li
Summary: Adults with chronic diseases often face a decline in quality of life and frequent exacerbations, which can cause anxiety and impose a significant economic burden. Self-management outside of the hospital is crucial for improving quality of life and reducing the financial burden of unexpected hospitalizations. With the COVID-19 pandemic, telehealth has become essential, as in-person appointments have been canceled, leading to increased reliance on online resources. This article discusses traditional self-management and modern telehealth strategies for chronic disease management, compares before and after the COVID-19 outbreak, and highlights emerging challenges.
FRONTIERS IN PUBLIC HEALTH
(2023)
Article
Clinical Neurology
Carly Olszewski, Sharon Thomson, Kelly Pring, Siobhan Cox, Rebecca Merrill, Emily Fishman, Alexander Ambrosini, Kevin Alexander Soltany, Gabby Bognet, Lauren Strauss, Rachel Graham, Amy Guzik, Roy E. Strowd
Summary: Patients consider factors such as the pros and cons of different visit types, barriers to telemedicine, situational context, inherent beliefs, and extrinsic variables when choosing between in-person, video, or telephone visits. They perceive convenience and monitoring of stable conditions as advantages of telemedicine, while improved quality of care and physical examination are associated with in-person visits. Accessibility, user familiarity, and system limitations are identified as barriers to telemedicine. Patients with in-person visits need to be more aware of telemedicine. Implementing hybrid models that incorporate telemedicine as an adjunct to in-person visits in ambulatory neurology is recommended.
JOURNAL OF NEUROLOGY
(2022)
Article
Health Care Sciences & Services
Elizabeth D. Ferucci, Rabecca Arnold, Peter Holck
Summary: This study assessed the differences in healthcare utilization between ever users of telemedicine for chronic disease specialty care and propensity-matched controls. The results showed that telemedicine users had higher rates of hospitalizations and outpatient visits, but potentially lower rates of emergency department visits.
JOURNAL OF TELEMEDICINE AND TELECARE
(2022)
Article
Geriatrics & Gerontology
Takako Fujita, Akira Babazono, Sung-a Kim, Aziz Jamal, Yunfei Li
Summary: Regular physician visits for patients with Parkinson's disease are significantly associated with longer survival time, fewer inpatient days, and lower healthcare costs. Caregivers should support patients in maintaining regular visits to physicians for their treatment.
Article
Medicine, Research & Experimental
Erin E. Krebs, William C. Becker, David Nelson, Beth M. DeRonne, Sean Nugent, Agnes C. Jensen, Erin C. Amundson, Jennifer K. Manuel, Brian Borsari, Allyson M. Kats, Karen H. Seal
Summary: The Veterans' Pain Care Organizational Improvement Comparative Effectiveness (VOICE) study is a 12-month trial conducted at ten United States Veterans Affairs (VA) health care sites, aiming to test interventions to improve pain while reducing opioid use among VA patients. The study faced challenges from opioid prescribing trends and the COVID-19 pandemic but successfully recruited eligible patients. The results will provide limited evidence for interventions to improve pain and reduce opioid use.
CONTEMPORARY CLINICAL TRIALS
(2023)
Article
Clinical Neurology
Craig S. Rosen, Adam N. Kaplan, David B. Nelson, Heidi La Bash, Kathleen M. Chard, Afsoon Eftekhari, Shannon Kehle-Forbes, Shannon Wiltsey Stirman, Nina A. Sayer
Summary: This study assessed longitudinal changes in burnout among psychotherapists before and during the COVID-19 pandemic. It found that burnout prevalence increased during the pandemic and organizational support for evidence-based psychotherapies reduced burnout risk prior to the pandemic.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Article
Public, Environmental & Occupational Health
Shannon Wiltsey Stirman, Heidi La Bash, David Nelson, Robert Orazem, Abigail Klein, Nina A. Sayer
Summary: This paper describes the strategies used by the US Department of Veterans Affairs (VA) to understand adherence and modifications to evidence-based psychotherapies (EBPs) for Posttraumatic Stress Disorder (PTSD) using clinical documentation and administrative data. The study found that a combination of manual chart review and administrative data allowed for the identification of different types of modifications, and that therapists and patients contributed to the variance in modifications. However, scalable strategies are needed to document adaptations and modifications to EBPs in routine care.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Medicine, General & Internal
Arianne K. Baldomero, Ken M. Kunisaki, Chris H. Wendt, Ann Bangerter, Susan J. Diem, Kristine E. Ensrud, David B. Nelson, Carrie Henning-Smith, Bradley A. Bart, Patrick Hammett, Hildi J. Hagedorn, R. Adams Dudley
Summary: This study used data from the National Veterans Health Administration and Medicare to assess the impact of drive time on the receipt of guideline-recommended screening, diagnosis, and treatment interventions. The study found that longer drive time was associated with lower rates of receiving recommended services.
Article
Medicine, Research & Experimental
Ryan E. Ferguson, Sarah M. Leatherman, Patricia Woods, Cynthia Hau, Robert Lew, William C. Cushman, Mary T. Brophy, Louis Fiore, Areef Ishani, DCP Grp
Summary: The study compared the effectiveness of hydrochlorothiazide and chlorthalidone in reducing major cardiovascular events in hypertensive patients. The success of the study relied on collaboration among researchers, regulators, clinicians, and administrative staff to align study procedures with local clinical practice. This research demonstrates the feasibility of leveraging clinical care for large-scale clinical trials, but requires rethinking traditional trial design and regulation to meet the needs of clinical care ecosystems.
Article
Medicine, Research & Experimental
Chi D. Chu, Kristin M. Lenoir, Nayanjot Kaur Rai, Sandeep Soman, Jamie P. Dwyer, Michael V. Rocco, Anil K. Agarwal, Srinivasan Beddhu, James R. Powell, Maritza M. Suarez, James P. Lash, Andrew McWilliams, Paul K. Whelton, Paul E. Drawz, Nicholas M. Pajewski, Areef Ishani, Delphine S. Tuot
Summary: The study compares electronic health record (EHR) data with trial-ascertained outcomes and finds that EHR data has high sensitivity and specificity in identifying cardiovascular disease events and is effective in capturing laboratory-based adverse events.
CONTEMPORARY CLINICAL TRIALS
(2023)
Article
Medicine, Research & Experimental
Sarah M. Leatherman, Cynthia Hau, Alison Klint, Peter A. Glassman, Addison A. Taylor, Ryan E. Ferguson, William C. Cushman, Areef Ishani
Summary: The impact of COVID-19 on decentralized pragmatic trials is unclear. This study assessed the impact of COVID-19 on recruitment, follow-up, data collection, and outcome ascertainment in the Diuretic Comparison Project (DCP). The findings showed that recruitment, enrollment, and adherence did not suffer during the pandemic.
CONTEMPORARY CLINICAL TRIALS
(2023)
Article
Medicine, Research & Experimental
Alison L. Klint, Sarah M. Leatherman, Olivia Taylor, Peter A. Glassman, Ryan E. Ferguson, William C. Cushman, Areef Ishani
Summary: Decentralized telephone consent can reduce the workload of clinical staff and facilitate a learning healthcare system. The Diuretic Comparison Project (DCP) aimed to compare the clinical effectiveness of two diuretics in an elderly patient population. Challenges in implementing telephone consent were addressed and lessons learned can benefit future clinical trials.
CONTEMPORARY CLINICAL TRIALS
(2023)
Article
Medicine, Research & Experimental
Srihari Raju, Cynthia Hau, Patricia Woods, Maura Flynn, Christal Sadatis, Jacob McPherson, Abhinav Tella, Areef Ishani, Ryan E. Ferguson, Sarah M. Leatherman
Summary: The goal of this observational study was to develop an algorithm for identifying stroke hospitalizations using ICD-10 codes, which can be used in clinical trials to eliminate the need for manual chart adjudication. A sample of 304 patient charts with ICD-10 codes indicating stroke were adjudicated and categorized. The study found that certain ICD-10 codes had a high positive predictive value for stroke hospitalizations.
CONTEMPORARY CLINICAL TRIALS
(2023)
Article
Urology & Nephrology
Daniel P. Murphy, Julian Wolfson, Scott Reule, Kirsten L. Johansen, Areef Ishani, Paul E. Drawz
Summary: This study found that ACEi/ARB use is associated with lower mortality in US military Veterans with diabetes, proteinuria, and AKI. Earlier initiation of ACEi/ARB therapy is favored.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
(2023)
Article
Mathematical & Computational Biology
Adam Kaplan, David Nelson
Summary: Missing outcomes are common in randomized controlled trials (RCTs) and can introduce bias in the analysis. We focus on binary outcomes that are possibly missing not at random. Anticipated response rates can be used to address these missing outcomes, especially when considering successful and unsuccessful treatment outcomes. We present Bayesian pattern-mixture models that incorporate information on response rates to analyze the relationship between a binary outcome and an intervention.
STATISTICS IN MEDICINE
(2023)
Article
Substance Abuse
Steven S. Fu, Dave Nelson, Tam Do, Diana J. Burgess, Christi A. Patten, Shu-Hong Zhu, Brian C. Martinson
Summary: This pilot study assessed the feasibility of two proactive outreach interventions to connect Vietnamese-speaking participants who smoke to the ASQ. The results showed that both proactive telephone outreach with interactive voice response (PRO-IVR) and proactive telephone outreach with a counselor trained in motivational interviewing (PRO-MI) were successful in promoting the initiation of smoking cessation treatment with the ASQ.
NICOTINE & TOBACCO RESEARCH
(2023)
Letter
Medicine, General & Internal
Franz H. Messerli
NEW ENGLAND JOURNAL OF MEDICINE
(2023)
Article
Respiratory System
Anne C. Melzer, Hildi Hagedorn, David Nelson, Adam Kaplan, Megan Campbell, Steven S. Fu
Summary: Despite overall increase in use, certain patient populations have persistently low technology use. This study examined access to, use of, and barriers surrounding information and communication technology (ICT) among patients with chronic obstructive pulmonary disease (COPD) who smoke, and evaluated associations between key predictors and electronic health (e-health) literacy. The findings indicate that many COPD patients face barriers to engagement with health promotion programs offered electronically, which may contribute to health disparities. Health promotion programs must address the low use of ICT and e-health literacy to ensure equitable access.
ANNALS OF THE AMERICAN THORACIC SOCIETY
(2023)
Review
Urology & Nephrology
Abhinav Tella, William Vang, Eustacia Ikeri, Olivia Taylor, Alicia Zhang, Megan Mazanec, Srihari Raju, Areef Ishani
Summary: This systematic review examined the use of different dialyzability beta-blockers in dialysis patients. The study found that highly dialyzable beta-blockers were associated with fewer cardiovascular events compared to poorly dialyzable beta-blockers in dialysis patients, without a significant impact on mortality.