Article
Obstetrics & Gynecology
Stephen Contag, Rahel Nardos, Irina A. Buhimschi, Jennifer Almanza
Summary: A study in Minnesota found that Somali women have longer gestational ages at delivery compared to other ethnic groups, resulting in higher risks for stillbirth and neonatal death rates. However, at 42 weeks, Somali neonatal mortality decreased and was comparable to that of the U.S. born White population, and lower than that of other minorities.
BMC PREGNANCY AND CHILDBIRTH
(2021)
Article
Obstetrics & Gynecology
Suzanne Thomas, Louise Stephens, Tracey A. Mills, Christine Hughes, Alan Kerby, Debbie M. Smith, Alexander E. P. Heazell
Summary: The study found that women experience heightened anxiety and depressive symptoms, as well as elevated cortisol levels during pregnancies after perinatal death, which decrease as the pregnancy progresses. Their health status also improves over time. Further research is needed to determine the best care for addressing these negative psychological consequences.
BMC PREGNANCY AND CHILDBIRTH
(2021)
Article
Public, Environmental & Occupational Health
Virginie Demiguel, Beatrice Blondel, Camille Bonnet, Viet Nguyen-Thanh, Marie-Josephe Saurel-Cubizolles, Nolwenn Regnault
Summary: The study described maternal smoking trends in France from 1972 to 2016, finding relatively stable proportions of mothers quitting smoking but high proportions of smokers during pregnancy. Smoking in the 3rd trimester from 2010 to 2016 was associated with lower education level and income, but the association with age, country of birth, and parity varied.
INTERNATIONAL JOURNAL OF PUBLIC HEALTH
(2021)
Article
Obstetrics & Gynecology
Rinat Levi, Gali Pariente, Eyal Sheiner, Tamar Wainstock
Summary: This study identified risk factors in first pregnancy for perinatal mortality in the subsequent pregnancy, concluding that complications in first pregnancy ending with live birth are associated with increased risk for perinatal mortality in a subsequent pregnancy.
INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS
(2022)
Article
Multidisciplinary Sciences
Rebecca Stone, Kirsten Palmer, Euan M. Wallace, Mary-Ann Davey, Ryan Hodges, Miranda Davies-Tuck
Summary: Early monitoring of South Asian pregnancies from 39 weeks' gestation with AFI and CTG can help identify potential fetal compromise earlier and trigger intervention to prevent perinatal issues.
SCIENTIFIC REPORTS
(2021)
Review
Public, Environmental & Occupational Health
Samira Behboudi-Gandevani, Razieh Bidhendi-Yarandi, Mohammad Hossein Panahi, Abbas Mardani, Ingjerd Gare Kymre, Piret Paal, Mojtaba Vaismoradi
Summary: Immigrant women in host countries have a higher risk of stillbirth, perinatal, and neonatal mortality compared to native-origin women. This study emphasizes the need for healthcare providers and policymakers to improve maternal and neonatal healthcare for the immigrant population.
INTERNATIONAL JOURNAL OF PUBLIC HEALTH
(2022)
Article
Public, Environmental & Occupational Health
Y. K. Mok, Mimi T. Y. Seto, Theodora H. T. Lai, W. Wang, K. W. Cheung
Summary: The study aimed to evaluate the trend of stillbirth from 2009 to 2018, finding a stable stillbirth rate over this period. The use of ICD-PM coding was effective in reducing the proportion of unexplained stillbirths and providing information on the timing of stillbirth and associated maternal conditions.
Article
Obstetrics & Gynecology
Jerome Cornette, Catharina J. van der Stok, Irwin K. M. Reiss, Rene F. Kornelisse, Eline van der Wilk, Arie Franx, Yves Jacquemyn, Eric A. P. Steegers, Loes C. M. Bertens
Summary: This study analyzed data from the Netherlands from 2014 to 2017 and found that the lowest risk of adverse neonatal outcomes occurred at 39 and 40 weeks of gestation, while the rates of adverse maternal outcomes continued to increase with each gestational week.
ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA
(2023)
Article
Obstetrics & Gynecology
Eskinder Kebede, Melani Kekulawala
Summary: Ethiopia has made significant improvements in reducing maternal and under-five mortality rates, but still struggles with high rates of perinatal mortality. Risk factors such as low maternal education, history of previous stillbirths/preterm births, and antepartum hemorrhaging are associated with stillbirths and early neonatal deaths. Antepartum hemorrhaging is the only intervenable risk factor identified in the study, highlighting the importance of improving patient education and antenatal care services to reduce perinatal mortality rates.
BMC PREGNANCY AND CHILDBIRTH
(2021)
Article
Oncology
Mahdi Sheikh, Shama Virani, Hilary A. Robbins, Lenka Foretova, Ivana Holcatova, Vladimir Janout, Jolanta Lissowska, Marie Navratilova, Anush Mukeriya, Miodrag Ognjanovic, Beata Swiatkowska, David Zaridze, Paul Brennan
Summary: This study investigated the survival and prognostic factors of surgically-resected early-stage non-small cell lung cancer (NSCLC) in Central and Eastern Europe. The 5-year survival rate was 49.5%, and age, gender, weight loss, smoking, alcohol drinking, and tumor stage were associated with the risk of death. Smoking and alcohol drinking showed a dose-dependent association with cancer-specific mortality.
Article
Obstetrics & Gynecology
Amy Hough, Haleema Shakur-Still, Ian Roberts, Artemis Koukounari, Joy E. Lawn
Summary: Women with PPH have high rates of stillbirth and slightly elevated PDNM, associated with severity markers and impacts on QoL.
INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS
(2021)
Article
Immunology
Almahamoudou Mahamar, Naissem Andemel, Bruce Swihart, Youssoufa Sidibe, Santara Gaoussou, Amadou Barry, Moussa Traore, Oumar Attaher, Adama B. Dembele, Bacary S. Diarra, Sekouba Keita, Alassane Dicko, Patrick E. Duffy, Michal Fried
Summary: This study in high transmission areas of Mali found that malaria infection during pregnancy increased the risks of stillbirth, preterm delivery, and early neonatal death. While treatment and preventive measures can reduce infections, they are insufficient to prevent severe outcomes. New tools are needed to improve pregnancy outcomes in malaria-endemic areas.
CLINICAL INFECTIOUS DISEASES
(2021)
Article
Multidisciplinary Sciences
Jialu Qian, Honghe Wu, Shiwen Sun, Man Wang, Xiaoyan Yu
Summary: The study translated the Perinatal Bereavement Care Confidence Scale (PBCCS) into Chinese and confirmed its validity and reliability for use with Chinese midwives and nurses. The results indicated that the Chinese version of PBCCS, known as C-PBCCS, is a psychometrically sound measurement tool that can evaluate the confidence and psychosocial factors affecting Chinese-speaking midwives' and nurses' ability to provide perinatal bereavement care.
Article
Medicine, Research & Experimental
Siobhan A. Loughnan, Frances M. Boyle, David Ellwood, Sara Crocker, Ann Lancaster, Chrissie Astell, Julie Dean, Dell Horey, Emily Callander, Claire Jackson, Antonia Shand, Vicki Flenady
Summary: This study aims to evaluate the efficacy and acceptability of a self-guided internet-based perinatal bereavement support program, Living with Loss (LWL), in reducing psychological distress and improving the wellbeing of parents following stillbirth or neonatal death. Through a randomized controlled trial, the research seeks to provide evidence of the role digital services may play in addressing the gap in specific bereavement support resources for parents following the death of a baby.
Article
Pediatrics
Milton W. Musaba, Brendah Nambozo, David Mukunya, Julius Wandabwa, Justus K. Barageine, Paul Kiondo, Agnes Napyo, Quraish Sserwanja, Andrew D. Weeks, James K. Tumwine, Grace Ndeezi
Summary: In high resource settings, lactate and pH levels from fetal scalp and umbilical cord blood are used as predictors of perinatal mortality. However, this practice is not common in low resource settings where most perinatal deaths occur due to difficulties in collecting samples. This study aimed to compare maternal and umbilical cord blood lactate levels for predicting perinatal deaths.
Letter
Medicine, General & Internal
Beth L. Pineles, Katherine E. Goodman, Lisa Pineles, Lyndsay M. O'Hara, Gita Nadimpalli, Laurence S. Magder, Jonathan D. Baghdadi, Jacqueline G. Parchem, Anthony D. Harris
ANNALS OF INTERNAL MEDICINE
(2021)
Article
Microbiology
Jonathan D. Baghdadi, K. C. Coffey, Timileyin Adediran, Katherine E. Goodman, Lisa Pineles, Larry S. Magder, Lyndsay M. O'Hara, Beth L. Pineles, Gita Nadimpalli, Daniel J. Morgan, Anthony D. Harris
Summary: Bacterial coinfection is common in hospitalized COVID-19 patients, but secondary infections are relatively rare. Most patients with COVID-19 receive antibiotic therapy during hospitalization, including 71% of those who are not diagnosed with bacterial infection.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
(2021)
Article
Pediatrics
Beth Pineles, Arunmani Mani, Livia Sura, Candace Rossignol, Mehmet Albayram, Michael David Weiss, Laura Goetzl
Summary: Central nervous system biomarkers derived from CNS exosomes in peripheral blood of newborns less than 12 hours old undergoing hypothermia for hypoxic-ischemic encephalopathy differentiated those with favorable and unfavorable MRI injury scores at 5-7 days in an observational cohort study. Our results suggest that CNS exosome cargo has the potential to act as biomarkers of brain injury severity and response to therapeutic hypothermia, as well as quantify pharmacological response to neuroactive therapeutic/adjuvant agents. Rigorous prospective trials are critical to evaluate the potential clinical use of exosome biomarkers.
ARCHIVES OF DISEASE IN CHILDHOOD-FETAL AND NEONATAL EDITION
(2022)
Article
Obstetrics & Gynecology
B. L. Pineles, A. Stephens, L. M. Narendran, M. A. Tigner, C. Leidlein, C. Pedroza, H. Mendez-Figueroa, B. M. Sibai
Summary: The study found that delivery improves the P/F ratio in pregnant patients with COVID-19-related ARDS, highlighting the need for individualized delivery management in these patients.
BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY
(2022)
Article
Obstetrics & Gynecology
Rigoberto Gutierrez, Hector Mendez-Figueroa, John G. Biebighauser, Asha Bhalwal, Beth L. Pineles, Suneet P. Chauhan
Summary: This study aimed to evaluate the composite maternal and neonatal outcomes in pregnant individuals with COVID-19 treated with remdesivir. The results showed that remdesivir was safe and well tolerated in pregnant women, with no recorded adverse reactions.
JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE
(2022)
Article
Obstetrics & Gynecology
Beth L. Pineles, Katherine E. Goodman, Lisa Pineles, Lyndsay M. O'Hara, Gita Nadimpalli, Laurence S. Magder, Jonathan D. Baghdadi, Jacqueline G. Parchem, Anthony D. Harris
Summary: Pregnant patients hospitalized with COVID-19 have lower in-hospital mortality rates compared to nonpregnant patients, despite a higher frequency of ICU admission.
OBSTETRICS AND GYNECOLOGY
(2022)
Article
Obstetrics & Gynecology
Beth L. Pineles, Jennie Coselli, Tala Ghorayeb, Michal Fishel Bartal, Rodrick C. Zvavanjanja, Sean C. Blackwell, Ramesha Papanna, Baha M. Sibai
Summary: This study describes the course and outcomes of patients with placenta accreta spectrum (PAS) managed by leaving the placenta in situ. The approach of delivering the fetus via cesarean and not attempting placental removal resulted in successful uterine preservation in a majority of patients. This management strategy could be considered for carefully selected patients with PAS.
AMERICAN JOURNAL OF PERINATOLOGY
(2022)
Letter
Medicine, General & Internal
Beth L. Pineles, Anthony D. Harris, Katherine E. Goodman
Summary: This study compares morbidity and delivery outcomes among pregnant 10- to 13-year-olds, 14- to 17-year-olds, and 18- to 19-year-olds using a US claims database.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
(2022)
Review
Obstetrics & Gynecology
Tabassum Firoz, Beth Pineles, Nishika Navrange, Alyssa Grimshaw, Olufemi Oladapo, Doris Chou
Summary: The definition and operationalization of NCDs in maternal health setting vary significantly. Existing literature is predominantly from high-income countries, focusing on the pre-conception period and pregnancy, while publications from low- and middle-income countries emphasize NCD prevention and integration of maternal and NCD services. Standardizing the definition and improving the articulation of care for NCDs would enhance data collection, monitoring, and resource allocation.
BMC PREGNANCY AND CHILDBIRTH
(2022)
Article
Immunology
Beth L. Pineles, Katherine E. Goodman, Lisa Pineles, Anthony D. Harris
Summary: This study estimated prophylactic antibiotic usage rates for the prevention of early-onset invasive neonatal group B Streptococcus infection among patients with penicillin allergy. Undertreatment and overtreatment were common, with academic hospitals showing slight adherence to guidelines over nonacademic hospitals.
OPEN FORUM INFECTIOUS DISEASES
(2022)
Article
Obstetrics & Gynecology
Brianna DuBose, Yazmeen Tembunde, Katherine E. Goodman, Lisa Pineles, Gita Nadimpalli, Jonathan D. Baghdadi, Jacqueline G. Parchem, Anthony D. Harris, Beth L. Pineles
Summary: This study aimed to evaluate the associations between COVID-19 and pregnancy outcomes. The results showed that COVID-19 patients had a higher risk of preterm delivery and stillbirth, with an even higher risk for those with viral pneumonia. However, COVID-19 did not have a significant impact on the risk of cesarean delivery and preeclampsia.
AMERICAN JOURNAL OF OBSTETRICS & GYNECOLOGY MFM
(2023)
Letter
Obstetrics & Gynecology
Lindsay L. Weitzel, Kendall G. Howen, Baha M. Sibai, Suneet P. Chauhan, Beth L. Pineles
AMERICAN JOURNAL OF OBSTETRICS & GYNECOLOGY MFM
(2023)
Article
Obstetrics & Gynecology
Beth L. Pineles, Mallory Vial, Tania Castro, Tala Ghorayeb, Oluwadare Ajishegiri, Sandra Sadek, Claudia Pedroza, Sean C. Blackwell, Suneet P. Chauhan, Baha M. Sibai
Summary: This study aimed to evaluate whether encouragement to ambulate at least 2000 steps daily affects latency among individuals with preterm prelabor rupture of membranes compared with usual care. The results showed that individuals encouraged to ambulate had a longer latency to delivery and improved neonatal and mental health outcomes, with similar maternal clinical outcomes compared to usual care.
AMERICAN JOURNAL OF OBSTETRICS & GYNECOLOGY MFM
(2024)
Article
Obstetrics & Gynecology
Beth L. Pineles, Hector Mendez-Figueroa, Suneet P. Chauhan
Summary: This study aimed to compare the adverse outcomes of neonates and mothers with detected and undetected small for gestational age. The results showed that although undetected small for gestational age had some complications, antenatal detection of small for gestational age was not associated with improved neonatal adverse outcomes.
AMERICAN JOURNAL OF OBSTETRICS & GYNECOLOGY MFM
(2022)
Article
Computer Science, Artificial Intelligence
Paul Fergus, Carl Chalmers, Casimiro Curbelo Montanez, Denis Reilly, Paulo Lisboa, Beth Pineles
Summary: This study proposed a novel method for analyzing cardiotocography (CTG) traces using machine learning models and one dimensional convolutional neural network (1DCNN), which can effectively distinguish between normal and pathological birth outcomes, improving accuracy and efficiency in analysis.
IEEE TRANSACTIONS ON EMERGING TOPICS IN COMPUTATIONAL INTELLIGENCE
(2021)