4.7 Article

rcellminer: exploring molecular profiles and drug response of the NCI-60 cell lines in R

Journal

BIOINFORMATICS
Volume 32, Issue 8, Pages 1272-1274

Publisher

OXFORD UNIV PRESS
DOI: 10.1093/bioinformatics/btv701

Keywords

-

Funding

  1. NIH, MSKCC Genome Data Analysis Center [U24 CA143840]
  2. Ruth L. Kirschstein National Research Service Award [F32 CA192901]
  3. Center for Cancer Research, Intramural Program of the National Cancer Institute [Z01 BC006150]

Ask authors/readers for more resources

Purpose: The rcellminer R package provides a wide range of functionality to help R users access and explore molecular profiling and drug response data for the NCI-60. The package enables flexible programmatic access to CellMiner's unparalleled breadth of NCI-60 data, including gene and protein expression, copy number, whole exome mutations, as well as activity data for 21K compounds, with information on their structure, mechanism of action and repeat screens. Functions are available to easily visualize compound structures, activity patterns and molecular feature profiles. Additionally, embedded R Shiny applications allow interactive data exploration.

Authors

I am an author on this paper
Click your name to claim this paper and add it to your profile.

Reviews

Primary Rating

4.7
Not enough ratings

Secondary Ratings

Novelty
-
Significance
-
Scientific rigor
-
Rate this paper

Recommended

No Data Available
No Data Available