Journal
BIOINFORMATICS
Volume 32, Issue 8, Pages 1272-1274Publisher
OXFORD UNIV PRESS
DOI: 10.1093/bioinformatics/btv701
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Funding
- NIH, MSKCC Genome Data Analysis Center [U24 CA143840]
- Ruth L. Kirschstein National Research Service Award [F32 CA192901]
- Center for Cancer Research, Intramural Program of the National Cancer Institute [Z01 BC006150]
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Purpose: The rcellminer R package provides a wide range of functionality to help R users access and explore molecular profiling and drug response data for the NCI-60. The package enables flexible programmatic access to CellMiner's unparalleled breadth of NCI-60 data, including gene and protein expression, copy number, whole exome mutations, as well as activity data for 21K compounds, with information on their structure, mechanism of action and repeat screens. Functions are available to easily visualize compound structures, activity patterns and molecular feature profiles. Additionally, embedded R Shiny applications allow interactive data exploration.
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