Article
Obstetrics & Gynecology
Chaitali Ghosh, Martha Wojtowycz
Summary: Many modifiable maternal behaviors and experiences before and during pregnancy are associated with adverse health outcomes. The study found that previous preterm birth and vaginal bleeding were independent high-risk factors for all three perinatal outcomes, with pre-pregnancy diabetes and gestational hypertension also being significant risk factors.
ARCHIVES OF GYNECOLOGY AND OBSTETRICS
(2021)
Review
Pediatrics
Megan Dibble, Jin Zhe Ang, Liam Mariga, Eleanor J. Molloy, Arun L. W. Bokde
Summary: White matter abnormalities, as measured by diffusion tensor imaging, are more significant in very preterm infants compared to moderate-late preterm infants and full-term controls at term-equivalent age. These microstructural changes may contribute to the increased risk of neurodevelopmental disability in preterm infants later in life, making diffusion tensor imaging a potentially useful prognostic tool.
JOURNAL OF PEDIATRICS
(2021)
Article
Medicine, General & Internal
Yulika Yoshida-Montezuma, Branavan Sivapathasundaram, Hilary K. Brown, Charles Keown-Stoneman, Russell J. de Souza, Teresa To, Cornelia M. Borkhoff, Catherine S. Birken, Jonathon L. Maguire, Laura N. Anderson
Summary: Children born late preterm and moderately preterm have higher cardiometabolic risk, suggesting that screening and early-life interventions for these children may prevent cardiometabolic outcomes.
Article
Pediatrics
Mary Anne J. Ryan, Sean R. Mathieson, Vicki Livingstone, Marc Paul O'Sullivan, Eugene M. Dempsey, Geraldine B. Boylan
Summary: This prospective observational study examines the nocturnal sleep architecture of healthy moderate to late preterm infants at 36 weeks post menstrual age. The study finds that sleep state architecture is dependent on birth GA, with infants born at lower GA having less active sleep and more quiet sleep. These findings may have implications for the neurodevelopment of the infants.
PEDIATRIC RESEARCH
(2023)
Article
Psychology, Multidisciplinary
Siri Weider, Astrid M. W. Laerum, Kari Anne I. Evensen, Solveig Klaebo Reitan, Stian Lydersen, Ann Mari Brubakk, Jon Skranes, Marit S. Indredavik
Summary: This study aimed to assess neurocognitive function in adults born with low birthweight compared with controls and explore associations between neurocognitive function and psychopathology in these groups. The results showed that the very low birthweight group scored significantly lower than the control group on multiple neurocognitive measures, while the small for gestational age group scored lower on IQ and psychomotor speed. Adjusted for sex and parental socioeconomic status, lower IQ was associated with attention problems. These findings have important clinical implications.
FRONTIERS IN PSYCHOLOGY
(2023)
Article
Pediatrics
Sara C. Handley, Elizabeth G. Salazar, Lucy T. Greenberg, Elizabeth E. Foglia, Scott A. Lorch, Erika M. Edwards
Summary: This study examines the delivery room management of moderate and late preterm infants. The study finds that the frequency of delivery room interventions decreases with increasing gestational age and varies across hospitals. The study also highlights the differing interpretation of resuscitation guidelines and the need for further research to improve evidence-based care for preterm infants in the delivery room.
Article
Pediatrics
Henriette Paulsen, Ulf Wike Ljungblad, Kirsti Riiser, Kari Anne I. Evensen
Summary: This study compared the neurological and motor function of preterm, term SGA, and term AGA infants and found subtle differences in neurological function between preterm and term AGA infants in infancy. At two years, preterm infants had poorer gross motor function. These findings suggest that moderate prematurity poses a risk for neurological deficits not only during the first year, but also at two years of age.
Review
Pediatrics
Lexuri Fernandez de Gamarra-Oca, Natalia Ojeda, Ainara Gomez-Gastiasoro, Javier Pena, Naroa Ibarretxe-Bilbao, M. Acebo Garcia-Guerrero, Begona Loureiro, Leire Zubiaurre-Elorza
Summary: Despite some inconsistencies due to methodological differences, individuals born moderate and late preterm (MLPT) show minor long-term effects into adulthood. More studies are needed to explore the vulnerability of prematurity to adverse neurodevelopment outcomes influenced by biological and environmental factors.
JOURNAL OF PEDIATRICS
(2021)
Article
Pediatrics
Fabianne M. N. A. Dantas, Paulo A. F. Magalhaes, Emilly C. N. Hora, Livia B. Andrade, Jose Angelo Rizzo, Decio M. Peixoto, Emanuel S. C. Sarinho
Summary: The study found that lung mechanics parameters were similar in school-age children born moderate-to-late preterm (MLPT) and those born at term, indicating that pulmonary plasticity continues to occur in children up to school age. Late and moderate prematurity is associated with an increased risk of reduced pulmonary function during childhood, but reports on adolescents and adults born MLPT have shown normalization of airway function and pulmonary plasticity.
PEDIATRIC RESEARCH
(2022)
Article
Pediatrics
Mary Anne Ryan, Deirdre M. Murray, Eugene M. Dempsey, Sean R. Mathieson, Vicki Livingstone, Geraldine B. Boylan
Summary: This study aimed to describe the neurodevelopmental outcomes of healthy low-risk moderate to late preterm infants at 18 months of age and compare them to term-born infants. The results showed that moderate to late preterm infants scored significantly lower in eye-hand coordination, personal, social and emotional development, gross motor development, general developmental, and foundations of learning. This suggests that they are at risk of suboptimal neurodevelopmental outcomes.
FRONTIERS IN PEDIATRICS
(2023)
Article
Nutrition & Dietetics
Mariana Muelbert, Tanith Alexander, Chris Pook, Yannan Jiang, Jane Elizabeth Harding, Frank Harry Bloomfield
Summary: In this study, the researchers used Near-Infrared Spectroscopy to observe the responses of preterm babies to smell and taste before receiving gastric tube feeds. The results showed that tube feeds activated the orbitofrontal cortex, but sensory stimulation alone did not activate it. Boys showed more response to the smell of milk. Further research is needed to determine the impact of sensory stimulation on nutrition and the influence of environmental inputs on cortical activation in preterm babies.
Article
Pediatrics
Giulia Vizzari, Daniela Morniroli, Valentina Tiraferri, Marta Macchi, Silvana Gangi, Alessandra Consales, Federica Ceroni, Jacopo Cerasani, Fabio Mosca, Maria Lorella Gianni
Summary: This study examined the growth outcomes of late preterm infants and identified factors associated with failure to recover growth. The results showed that 34% of children did not regain weight at 36 months. Infants who did not regain weight at 12 months were at a higher risk of not regaining weight at 36 months. The same risk factor was also associated with length catch-up growth. Additionally, infants fed any human milk at discharge were protected from failure to achieve weight and length catch-up growth at 36 months.
PEDIATRIC RESEARCH
(2023)
Article
Pediatrics
Teniola Egbe, Diana Montoya-Williams, Kate Wallis, Molly Passarella, Scott A. Lorch
Summary: This retrospective study in Pennsylvania found that foreign-born women overall had lower relative risks of preterm birth, but the risk varied by preterm strata and by race when considering maternal race, ethnicity, and nativity. It suggests that race, ethnicity, and nativity contribute differently to varying levels of prematurity. Further research may benefit from a more detailed approach to studying preterm birth outcomes and considering the interaction between nativity, race, and ethnicity.
JOURNAL OF PEDIATRICS
(2022)
Article
Pediatrics
Grace E. McMahon, Karli Treyvaud, Megan M. Spencer-Smith, Alicia J. Spittle, Katherine J. Lee, Lex W. Doyle, Jeanie L. Cheong, Peter J. Anderson
Summary: This study compared the parenting environment and the relationships between parenting behaviors and neurobehavioral outcomes at 2 years of corrected age between children born moderate-to-late preterm and at term. The results showed that parenting behaviors were important for neurobehavioral outcomes in both groups, with language development being more strongly influenced by select parenting behaviors in children born moderate-to-late preterm.
JOURNAL OF PEDIATRICS
(2022)
Article
Gastroenterology & Hepatology
Raakel Luoto, Anna Paertty, Josef K. Vogt, Samuli Rautava, Erika Isolauri
Summary: This study investigated the composition and function of the gut microbiome in moderately and late preterm infants. Probiotic and prebiotic treatments were found to mitigate the changes in the microbiome, indicating their potential in promoting healthy gut microbiome development in preterm infants.
Article
Medicine, General & Internal
Lina H. Raffa, Nasser T. Balbaid, Mariam M. Ageel
Summary: This study evaluated the validity of a smartphone-based application for visual acuity testing in children and compared parent and clinician-performed testing to standard assessment. The results showed that the application had good sensitivity in detecting subnormal visual acuity but lower sensitivity in detecting amblyopia.
SAUDI MEDICAL JOURNAL
(2022)
Article
Pediatrics
Lina H. Raffa, Omar M. Akeely, Saleh A. Alariefy, Faisal A. Alharbi, Moussa A. Alkhateeb, Mohammad A. Khan
Summary: The study aimed to validate the accuracy of the Alexandria ROP and high-grade Alex-ROP models in predicting treatable ROP in a cohort of preterm infants in Saudi Arabia. The results showed that the sensitivity and specificity of the Alex-ROP model were relatively low in detecting ROP, indicating that it may not be reliable in identifying infants requiring treatment.
JOURNAL OF CLINICAL NEONATOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Anas Raffa, Lina Raffa, Yumna Kamal, Tasneem Hassan, Khadija Alaidarous, Majed Osaylan, Nawaf Almarzouki
Summary: This study aimed to establish the normal measurements of optic nerve diameter (OND), optic nerve sheath diameter (ONSD), and eyeball transverse diameter (ETD) in children and explore the associations with age and sex. The results showed that ONSD and ETD were wider in boys compared to girls and were significantly influenced by age. The findings of this study are important for the diagnosis of pediatric diseases.
Article
Ophthalmology
Lina Raffa, Ola Abudawd, Nada Bugshan, Samiha Fageeh, Lucia Ramos, Jorge Novo, Jose Rouco, Marcos Ortega
Summary: Retinal vessel tortuosity parameters were measured using a new software in moderate-to-late preterm children, and it was found that the arteriolar caliber in the preterm group was smaller compared to full-term children, while the tortuosity parameters did not differ significantly between the two groups.
EUROPEAN JOURNAL OF OPHTHALMOLOGY
(2023)
Article
Ophthalmology
Lina Raffa, Aliaa Alamri, Amal Alosaimi, Sarah Alessa, Suzan Alharbi, Huda Ahmedhussain, Hashem Almarzouki, Mansour AlQurashi
Summary: This study evaluated the accuracy of three different predictive algorithms in detecting retinopathy of prematurity in preterm infants in a developing country. The results showed that WINROP and ROPScore had high sensitivity for type 1 retinopathy of prematurity, but low specificity.
INDIAN JOURNAL OF OPHTHALMOLOGY
(2023)
Article
Ophthalmology
Lina Hassan Raffa, Tala Musa Roblah, Nasser Talal Balbaid, Bader Sameer Zimmo, Mahmood Jameel Showail
Summary: This study examined the incidence of ocular abnormalities in children with atopic dermatitis in Saudi Arabia and its association with the severity of the condition. The majority of children with atopic dermatitis were found to have ocular abnormalities, mainly involving the eyelids. Larger scale studies are needed to determine the benefits of regular screening for ocular abnormalities in children with atopic dermatitis in terms of early intervention and prevention of sight-threatening complications.
INTERNATIONAL JOURNAL OF OPHTHALMOLOGY
(2023)
Article
Medicine, General & Internal
L. H. Raffa, N. Bugshan, R. Aljuhani, R. Alghoribi, A. Alharbi, W. Aljohani
Summary: The aim of this study was to validate the accuracy of the G-ROP criteria in screening preterm infants in Saudi Arabia. The results showed that the G-ROP 2 model was more sensitive in identifying infants who required treatment and could potentially reduce the burden of ROP screening, but it had lower specificity for diagnosing ROP.
NIGERIAN JOURNAL OF CLINICAL PRACTICE
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Lina Raffa, Khadijah Alattas, Omar Akeely, Mohammed Awadh
Summary: Retinopathy of prematurity (ROP) is a leading cause of blindness in infants, and it is important to raise awareness about this disease. This study evaluates the credibility of Arabic-language YouTube videos on ROP. Out of the 40 videos analyzed, only 29 were considered useful, and the overall quality of the content was poor. Although 70% of the videos were accurate, only 5% were fully comprehensive. The medical community could utilize the platform's high engagement to create entertaining and useful content for raising awareness about ROP.
JOURNAL OF VISUAL COMMUNICATION IN MEDICINE
(2023)
Article
Medicine, General & Internal
Rawan Tash, Reema Alshugaig, Heba Mahboob, Lina H. Raffa, Hanan Jamjoom, Nawaf Almarzouki, Ahmed Bawazeer
Summary: This study investigated the adherence of pediatric glaucoma patients to follow-up appointments at King Abdulaziz University Hospital in Jeddah, Saudi Arabia. The majority of patients were adherent to their appointments, but a significant percentage were non-adherent or lost to follow-up. Nationality, distance to the hospital, and number of prescribed ocular medications were identified as factors influencing adherence status.
CUREUS JOURNAL OF MEDICAL SCIENCE
(2023)
Article
Medicine, General & Internal
Lina H. Raffa, Wasayf Aljohani
Summary: This study investigates the association between blood transfusions and the development and severity of retinopathy of prematurity (ROP). It found that infants who received blood transfusions had a higher risk of developing ROP and experienced more complications compared to those who did not receive transfusions.
CUREUS JOURNAL OF MEDICAL SCIENCE
(2022)
Article
Ophthalmology
Nooran Badeeb, Lina Raffa, Huda Ahmed Hussain, Dania Bamefleh, Enas Mgharbil, Sarah Alessa, Aliaa Alamri, Mohamed Albahiti
Summary: The study identified maternal risk factors for retinopathy of prematurity (ROP) in Saudi Arabia, with spontaneous vaginal delivery, low birth weight (BW), and shorter gestational age being significant factors. Low BW was found to be the most predictive risk factor for both any stage and Type 1 ROP. These findings highlight the importance of obstetric care in modifying maternal risk factors to prevent preterm births associated with low BW.
TAIWAN JOURNAL OF OPHTHALMOLOGY
(2021)
Article
Medicine, General & Internal
L. H. Raffa, O. Abudaowd, N. Bugshan, S. N. Fagih, T. Hamdi
Summary: The study found significant differences in anterior chamber depth, central macular thickness, and central subfield thickness between moderate-to-late preterm and full-term groups. This suggests that preterm birth may have an impact on ocular structures. Larger population-based studies are needed to investigate the long-term effects of moderate-to-late prematurity in children.
NIGERIAN JOURNAL OF CLINICAL PRACTICE
(2021)
Article
Medicine, General & Internal
N. Almarzouki, S. Alessa, L. Raffa
Summary: This study analyzed the clinical features and demographics of 14 patients with endophthalmitis treated at King Abdulaziz University Hospital between 2002 and 2018. Post-ophthalmic surgery and endogenous endophthalmitis were the most common causes, with patients often presenting late after symptoms occurred.
NIGERIAN JOURNAL OF CLINICAL PRACTICE
(2021)
Meeting Abstract
Ophthalmology
Alexandra Lind, Eva Aring, Titus Ovik, Arzu Karatepe, Lina Raffa, Zoran Popovic, Jovanna Dahlgren, Marita Gronlund
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
(2021)
Article
Ophthalmology
Lina H. Raffa, Kareem Allinjawi, Sharanjeet-Kaur, Saadah M. Akhir, Haliza A. Mutalib
Summary: The study found that using Proclear +3.00D MFCL can slow down myopia progression and axial elongation. Higher add powers may be more effective in controlling myopia progression compared to moderate add powers.
SAUDI JOURNAL OF OPHTHALMOLOGY
(2021)