TGF-β1-induced transcription factor networks in Langerhans cell development and maintenance

Aging affects epidermal Langerhans cell development and function and alters their miRNA gene expression profile

(2016) Ying-Ping Xu et al.   Aging-US

The Late Endosomal Adaptor Molecule p14 (LAMTOR2) Regulates TGFβ1-Mediated Homeostasis of Langerhans Cells

(2015) Florian Sparber et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Human embryonic epidermis contains a diverse Langerhans cell precursor pool

(2014) C. Schuster et al.   DEVELOPMENT

The Transcription Factor IRF8 Activates Integrin-Mediated TGF-β Signaling and Promotes Neuroinflammation

(2014) Yuko Yoshida et al.   IMMUNITY

Tissue-resident macrophages originate from yolk-sac-derived erythro-myeloid progenitors

(2014) Elisa Gomez Perdiguero et al.   NATURE

TAM receptors in apoptotic cell clearance, autoimmunity, and cancer

(2013) Khanh-Quynh Nguyen et al.   AUTOIMMUNITY

The late endosomal adaptor molecule p14 (LAMTOR2) represents a novel regulator of Langerhans cell homeostasis

(2013) F. Sparber et al.   BLOOD

microRNA miR-17-92 cluster is highly expressed in epidermal Langerhans cells but not required for its development

(2013) L Zhou et al.   GENES AND IMMUNITY

Multicolor fate mapping of Langerhans cell homeostasis

(2013) Clément Ghigo et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Langerhans cells are generated by two distinct PU.1-dependent transcriptional networks

(2013) Michaël Chopin et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Identification of bone morphogenetic protein 7 (BMP7) as an instructive factor for human epidermal Langerhans cell differentiation

(2013) Nighat Yasmin et al.   JOURNAL OF EXPERIMENTAL MEDICINE

β-Catenin Promotes the Differentiation of Epidermal Langerhans Dendritic Cells

(2013) Nighat Yasmin et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

PU.1 Level-Directed Chromatin Structure Remodeling at the Irf8 Gene Drives Dendritic Cell Commitment

(2013) Jörg Schönheit et al.   Cell Reports

Langerhans cell homeostasis in mice is dependent on mTORC1 but not mTORC2 function

(2012) B. Kellersch et al.   BLOOD

Antigen presentation by Langerhans cells

(2012) Botond Z Igyártó et al.   CURRENT OPINION IN IMMUNOLOGY

Lack of microRNA miR-150 reduces the capacity of epidermal Langerhans cell cross-presentation

(2012) Qing-Sheng Mi et al.   EXPERIMENTAL DERMATOLOGY

Two Distinct Types of Langerhans Cells Populate the Skin during Steady State and Inflammation

(2012) Kristin Seré et al.   IMMUNITY

Deletion of microRNA miR-223 increases Langerhans cell cross-presentation

(2012) Qing-Sheng Mi et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Identification of Axl as a downstream effector of TGF-β1 during Langerhans cell differentiation and epidermal homeostasis

(2012) Thomas Bauer et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Adult Langerhans cells derive predominantly from embryonic fetal liver monocytes with a minor contribution of yolk sac–derived macrophages

(2012) Guillaume Hoeffel et al.   JOURNAL OF EXPERIMENTAL MEDICINE

MicroRNA miR-150 Is Involved in V 14 Invariant NKT Cell Development and Function

(2012) Q. Zheng et al.   JOURNAL OF IMMUNOLOGY

TGFβ/Smad3 Signal Pathway Is Not Required for Epidermal Langerhans Cell Development

(2012) Ying-Ping Xu et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Small RNAs have a large impact

(2012) Matthew Weiland et al.   RNA Biology

Regulation and function of the E-cadherin/catenin complex in cells of the monocyte-macrophage lineage and DCs

(2011) J. Van den Bossche et al.   BLOOD

MicroRNAs are key regulators controlling iNKT and regulatory T-cell development and function

(2011) Li Zhou et al.   Cellular & Molecular Immunology

Tight Control of STAT5 Activity Determines Human CD34-Derived Interstitial Dendritic Cell and Langerhans Cell Development

(2011) L. van de Laar et al.   JOURNAL OF IMMUNOLOGY

Uptake of apoptotic DC converts immature DC into tolerogenic DC that induce differentiation of Foxp3+Treg

(2010) Rahul Kushwah et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Langerhans cells and more: langerin-expressing dendritic cell subsets in the skin

(2010) Nikolaus Romani et al.   IMMUNOLOGICAL REVIEWS

Essential roles of SIRPα in homeostatic regulation of skin dendritic cells

(2010) Hiroko Iwamura et al.   IMMUNOLOGY LETTERS

Dicer-Dependent MicroRNAs Control Maturation, Function, and Maintenance of Langerhans Cells In Vivo

(2010) H. Kuipers et al.   JOURNAL OF IMMUNOLOGY

miR-146a Is Differentially Expressed by Myeloid Dendritic Cell Subsets and Desensitizes Cells to TLR2-Dependent Activation

(2010) J. Jurkin et al.   JOURNAL OF IMMUNOLOGY

TGF-  Is Required To Maintain the Pool of Immature Langerhans Cells in the Epidermis

(2010) J. M. Kel et al.   JOURNAL OF IMMUNOLOGY

PU.1-mediated upregulation of CSF1R is crucial for leukemia stem cell potential induced by MOZ-TIF2

(2010) Yukiko Aikawa et al.   NATURE MEDICINE

mTOR signaling at a glance

(2009) M. Laplante et al.   JOURNAL OF CELL SCIENCE

The origin and development of nonlymphoid tissue CD103+DCs

(2009) Florent Ginhoux et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Aryl Hydrocarbon Receptor Activation Inhibits In Vitro Differentiation of Human Monocytes and Langerhans Dendritic Cells

(2009) B. Platzer et al.   JOURNAL OF IMMUNOLOGY

Langerhans Cell Maturation and Contact Hypersensitivity Are Impaired in Aryl Hydrocarbon Receptor-Null Mice

(2009) B. Jux et al.   JOURNAL OF IMMUNOLOGY

Tie2cre-induced inactivation of the miRNA-processing enzyme Dicer disrupts invariant NKT cell development

(2009) L. Zhou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA