The safety of autologous and metabolically fit bone marrow mesenchymal stromal cells in medically refractory Crohn's disease - a phase 1 trial with three doses

Allogeneic Bone Marrow–Derived Mesenchymal Stromal Cells Promote Healing of Refractory Perianal Fistulas in Patients With Crohn’s Disease

(2015) Ilse Molendijk et al.   GASTROENTEROLOGY

Mesenchymal Stromal Cells Derived From Crohn's Patients Deploy Indoleamine 2,3-dioxygenase-mediated Immune Suppression, Independent of Autophagy

(2015) Raghavan Chinnadurai et al.   MOLECULAR THERAPY

IDO-Independent Suppression of T Cell Effector Function by IFN- -Licensed Human Mesenchymal Stromal Cells

(2014) R. Chinnadurai et al.   JOURNAL OF IMMUNOLOGY

Actin Cytoskeletal Disruption following Cryopreservation Alters the Biodistribution of Human Mesenchymal Stromal Cells In Vivo

(2014) Raghavan Chinnadurai et al.   Stem Cell Reports

A Phase 2 Study of Allogeneic Mesenchymal Stromal Cells for Luminal Crohn's Disease Refractory to Biologic Therapy

(2013) Geoffrey M. Forbes et al.   Clinical Gastroenterology and Hepatology

The mesenchymal stromal cells dilemma—does a negative phase III trial of random donor mesenchymal stromal cells in steroid-resistant graft-versus-host disease represent a death knell or a bump in the road?

(2013) Jacques Galipeau   CYTOTHERAPY

Treatment with mesenchymal stromal cells is a risk factor for pneumonia-related death after allogeneic hematopoietic stem cell transplantation

(2012) Ulrica Forslöw et al.   EUROPEAN JOURNAL OF HAEMATOLOGY

New insights on translational development of mesenchymal stromal cells for suppressor therapy

(2012) Moïra François et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Global transcriptome analysis of human bone marrow stromal cells (BMSC) reveals proliferative, mobile and interactive cells that produce abundant extracellular matrix proteins, some of which may affect BMSC potency

(2011) Jiaqiang Ren et al.   CYTOTHERAPY

Cryopreserved mesenchymal stromal cells display impaired immunosuppressive properties as a result of heat-shock response and impaired interferon-γ licensing

(2011) Moïra François et al.   CYTOTHERAPY

Autologous bone marrow-derived mesenchymal stromal cells in the treatment of fistulising Crohn's disease

(2011) R. Ciccocioppo et al.   GUT

Use of immunomodulators and biologic therapies in children with inflammatory bowel disease

(2010) Athos Bousvaros   Expert Review of Clinical Immunology

Immunogenicity of anti-TNF antibodies. Has the veil been lifted?

(2010) G. Van Assche   GUT

Autologous bone marrow-derived mesenchymal stromal cell treatment for refractory luminal Crohn's disease: results of a phase I study

(2010) Marjolijn Duijvestein et al.   GUT

Good Manufacturing Practices Production of Mesenchymal Stem/Stromal Cells

(2010) Luc Sensebé et al.   HUMAN GENE THERAPY

Casting Doubt on the Safety of “Off-the-shelf” Mesenchymal Stem Cells for Cell Therapy

(2009) Pranela Rameshwar   MOLECULAR THERAPY