FAAHGene Variation Moderates Stress Response and Symptom Severity in Patients with Posttraumatic Stress Disorder and Comorbid Alcohol Dependence

The Fatty Acid Amide Hydrolase C385A Variant Affects Brain Binding of the Positron Emission Tomography Tracer [11C]CURB

(2015) Isabelle Boileau et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Corticotropin-Releasing Hormone Drives Anandamide Hydrolysis in the Amygdala to Promote Anxiety

(2015) J. M. Gray et al.   JOURNAL OF NEUROSCIENCE

Stress-Induced Reinstatement of Drug Seeking: 20 Years of Progress

(2015) John R Mantsch et al.   NEUROPSYCHOPHARMACOLOGY

Neurobiological Interactions Between Stress and the Endocannabinoid System

(2015) Maria Morena et al.   NEUROPSYCHOPHARMACOLOGY

FAAH genetic variation enhances fronto-amygdala function in mouse and human

(2015) Iva Dincheva et al.   Nature Communications

Methods for inducing alcohol craving in individuals with co-morbid alcohol dependence and posttraumatic stress disorder: behavioral and physiological outcomes

(2014) Laura E. Kwako et al.   ADDICTION BIOLOGY

Therapeutic Potential of Inhibitors of Endocannabinoid Degradation for the Treatment of Stress-Related Hyperalgesia in an Animal Model of Chronic Pain

(2014) Ermelinda Lomazzo et al.   NEUROPSYCHOPHARMACOLOGY

The neurokinin-1 receptor antagonist aprepitant in co-morbid alcohol dependence and posttraumatic stress disorder: a human experimental study

(2014) Laura E. Kwako et al.   PSYCHOPHARMACOLOGY

Central anandamide deficiency predicts stress-induced anxiety: behavioral reversal through endocannabinoid augmentation

(2014) R J Bluett et al.   Translational Psychiatry

Elevated brain cannabinoid CB1 receptor availability in post-traumatic stress disorder: a positron emission tomography study

(2013) A Neumeister et al.   MOLECULAR PSYCHIATRY

Inhibition of FAAH and activation of PPAR: New approaches to the treatment of cognitive dysfunction and drug addiction

(2013) Leigh V. Panlilio et al.   PHARMACOLOGY & THERAPEUTICS

Reductions in circulating endocannabinoid levels in individuals with post-traumatic stress disorder following exposure to the world trade center attacks

(2013) Matthew N. Hill et al.   PSYCHONEUROENDOCRINOLOGY

Amygdala FAAH and anandamide: mediating protection and recovery from stress

(2013) Ozge Gunduz-Cinar et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Disruption of fatty acid amide hydrolase activity prevents the effects of chronic stress on anxiety and amygdalar microstructure

(2012) M N Hill et al.   MOLECULAR PSYCHIATRY

Reduced cannabinoid CB1 receptor binding in alcohol dependence measured with positron emission tomography

(2012) J Hirvonen et al.   MOLECULAR PSYCHIATRY

Convergent translational evidence of a role for anandamide in amygdala-mediated fear extinction, threat processing and stress-reactivity

(2012) O Gunduz-Cinar et al.   MOLECULAR PSYCHIATRY

Chronic alcohol remodels prefrontal neurons and disrupts NMDAR-mediated fear extinction encoding

(2012) Andrew Holmes et al.   NATURE NEUROSCIENCE

Acute Stress Increases Circulating Anandamide and Other N-Acylethanolamines in Healthy Humans

(2012) Andrea Dlugos et al.   NEUROPSYCHOPHARMACOLOGY

A polymorphism in the gene of the endocannabinoid-degrading enzyme FAAH (FAAH C385A) is associated with emotional–motivational reactivity

(2012) Annette Conzelmann et al.   PSYCHOPHARMACOLOGY

Effects of Adrenal Sensitivity, Stress- and Cue-Induced Craving, and Anxiety on Subsequent Alcohol Relapse and Treatment Outcomes

(2011) Rajita Sinha   ARCHIVES OF GENERAL PSYCHIATRY

Endocannabinoid signaling, glucocorticoid-mediated negative feedback, and regulation of the hypothalamic-pituitary-adrenal axis

(2011) M.N. Hill et al.   NEUROSCIENCE

Translational and reverse translational research on the role of stress in drug craving and relapse

(2011) Rajita Sinha et al.   PSYCHOPHARMACOLOGY

The endocannabinoid system and psychiatric disorders

(2010) Daniela Parolaro et al.   EXPERIMENTAL NEUROLOGY

Preservation of Striatal Cannabinoid CB1 Receptor Function Correlates with the Antianxiety Effects of Fatty Acid Amide Hydrolase Inhibition

(2010) S. Rossi et al.   MOLECULAR PHARMACOLOGY

Biomarkers of Endocannabinoid System Activation in Severe Obesity

(2010) Jack C. Sipe et al.   PLoS One

Endogenous cannabinoid signaling is essential for stress adaptation

(2010) M. N. Hill et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Selective alterations of the CB1 receptors and the fatty acid amide hydrolase in the ventral striatum of alcoholics and suicides

(2009) K. Yaragudri Vinod et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Suppression of Amygdalar Endocannabinoid Signaling by Stress Contributes to Activation of the Hypothalamic–Pituitary–Adrenal Axis

(2009) Matthew N Hill et al.   NEUROPSYCHOPHARMACOLOGY

Repeated Homotypic Stress Elevates 2-Arachidonoylglycerol Levels and Enhances Short-Term Endocannabinoid Signaling at Inhibitory Synapses in Basolateral Amygdala

(2009) Sachin Patel et al.   NEUROPSYCHOPHARMACOLOGY

Addictions Biology: Haplotype-Based Analysis for 130 Candidate Genes on a Single Array

(2008) C. A. Hodgkinson et al.   ALCOHOL AND ALCOHOLISM

Divergent Effects of Genetic Variation in Endocannabinoid Signaling on Human Threat- and Reward-Related Brain Function

(2008) Ahmad R. Hariri et al.   BIOLOGICAL PSYCHIATRY

Serum Endocannabinoid Content is Altered in Females with Depressive Disorders: A Preliminary Report

(2008) M. Hill et al.   PHARMACOPSYCHIATRY

Increase of brain endocannabinoid anandamide levels by FAAH inhibition and alcohol abuse behaviours in the rat

(2008) Andrea Cippitelli et al.   PSYCHOPHARMACOLOGY