Article
Multidisciplinary Sciences
Birhan Aynalem, Diriba Muleta, Mulissa Jida, Fekadu Shemekite, Fassil Aseffa
Summary: The study evaluated the effectiveness of entomopathogens and insecticides against Tuta absoluta, and found that all treatments significantly reduced leaf and fruit damage. When entomopathogens were combined with reduced concentrations of insecticide, they effectively controlled Tuta absoluta without adverse effects on tomato growth.
Article
Entomology
Marianna Stavrakaki, Aris Ilias, Panagiotis Ioannidis, John Vontas, Emmanouil Roditakis
Summary: The tomato borer Tuta absoluta has developed high resistance to the insecticide emamectin benzoate, with no non-synonymous SNPs detected in the target genes. The involvement of P450s in metabolic resistance to emamectin benzoate was suggested through enzyme inhibitor assays. RNA-seq analysis identified over-expression of a cytochrome P450-like gene potentially linked to emamectin benzoate resistance, expanding genomic resources for this species.
JOURNAL OF PEST SCIENCE
(2022)
Article
Plant Sciences
Daniela D'Esposito, Daniele Manzo, Alessandro Ricciardi, Antonio Pietro Garonna, Antonino De Natale, Luigi Frusciante, Francesco Pennacchio, Maria Raffaella Ercolano
Summary: The resilient response of tomato to the South America pinworm involves a combination of constitutive and induced defense mechanisms. The enhanced constitutive barrier in tolerant genotypes is attributed to factors such as increased density of trichomes and modulation of key transcription factors. These findings could be utilized to develop T. absoluta tolerant cultivars for more sustainable production.
Article
Plant Sciences
Limin Chen, Xiaowei Li, Jinming Zhang, Tianjun He, Jun Huang, Zhijun Zhang, Yeyang Wang, Muhammad Hafeez, Shuxing Zhou, Xiaoyun Ren, Youming Hou, Yaobin Lu
Summary: The study found differential accumulation of volatile organic compounds and metabolites in eggplants and tomatoes in response to Tuta absoluta infestation, with terpenes playing a key role in the differences observed. These differentially accumulated metabolites and volatile compounds are crucial in eggplant resistance to T. absoluta, indicating their significant impact on the behavior of this pest.
FRONTIERS IN PLANT SCIENCE
(2021)
Article
Agronomy
Gabriel Tadeu de Paiva Silva, Karolina Gomes Figueiredo, Dejane Santos Alves, Denilson Ferreira de Oliveira, Geraldo Humberto Silva, Gabriela Trindade Silva, Murilo Silva de Oliveira, Antonio Biondi, Geraldo Andrade Carvalho
Summary: The toxicity of essential oils from lime, petitgrain, and bergamot, as well as their major compounds, against T. absoluta was evaluated. The results showed that the essential oils were toxic to T. absoluta, and low concentrations caused deleterious effects on its reproductive and population parameters.
Article
Multidisciplinary Sciences
Ying Liu, Xi Chen, Yanqiong Yin, Xiaowei Li, Kang He, Xueqing Zhao, Xiangyong Li, Xiyan Luo, Yang Mei, Zuoqi Wang, Runguo Shu, Ziqi Cheng, Kifle Gebreegziabiher Gebretsadik, Chen Luo, Ran Wang, Yaobin Lv, Aidong Chen, Fei Li
Summary: The tomato pinworm, a destructive pest that threatens global tomato production, has been found to have a high-quality genome assembly through sequencing using Nanopore platforms. This assembly provides valuable gene resources and insights into the species' invasiveness and ecological adaptation. Furthermore, the Hi-C technique allowed for the construction of a chromosome-level genome assembly, facilitating future research on control strategies.
Article
Agricultural Engineering
Ana Maria Salazar, Nolberto Arismendi, Maria Dolores Lopez, Marisol Vargas, Mauricio Schoebitz, Daniel A. Palacio, Jose Becerra, Braulio Cedeno, Nelson Zapata
Summary: This study evaluated the stability and insecticidal effects of a nanoemulsion (NE) based on Laureliopsis philippiana essential oil against Tuta absoluta. The NE showed excellent stability and greater insecticidal activity against T. absoluta compared to the pure essential oil, particularly at low concentrations.
INDUSTRIAL CROPS AND PRODUCTS
(2022)
Article
Entomology
Reynardt Erasmus, Johnnie van den Berg, Hannalene du Plessis
Summary: The tomato pinworm is a destructive insect pest of tomatoes in Africa, with many farmers relying on chemical insecticides for control, leading to resistance issues. This study demonstrates the effectiveness of using entomopathogenic fungi as biopesticides, particularly against the pupal stage of the pest. Soil drench applications of Beauveria bassiana and Metarhizium anisopliae showed high mortality rates in pupae, reducing fecundity in surviving moths without affecting fertility. This research highlights the potential of using biopesticides in integrated pest management programs for controlling the tomato pinworm in different life stages.
Article
Agriculture, Multidisciplinary
Kouassi Arthur J. Konan, Anthelme J. N'cho, Marie-France N. Kouadio, Gabaze A. Gadji, Noupe D. Coulibaly, Mauricette S. -W. Ouali-N'Goran, Thibaud Martin
Summary: This study evaluated the insecticidal and repellent effects of Carapa oil on different stages of T. absoluta, a major pest of tomato crops. The results showed that Carapa oil had significant larvicidal and ovicidal effects, as well as a repellent effect on adult insects. It is considered a promising biopesticide for controlling T. absoluta.
JOURNAL OF PLANT DISEASES AND PROTECTION
(2023)
Article
Entomology
Peng Wang, Mei-Xin Zheng, Jing-Jing Li, Yang Yu, Ying Hu, Lucie S. Monticelli, Chang-Chun Ruan, Nicolas Desneux, Jun-jie Zhang
Summary: This study evaluated the impact of Beauveria bassiana on the oviposition preference and parasitic behavior of Trichogramma japonicum towards Chilo suppressalis eggs. The results showed that B. bassiana did not significantly affect the choices made by T. japonicum and suggested that T. japonicum can be used together with B. bassiana for integrated management of C. suppressalis.
JOURNAL OF PEST SCIENCE
(2023)
Article
Entomology
Sabrine Chouikhi, Besma Hamrouni Assadi, KaoutharGrissa Lebdi, Mohamed Sadok Belkadhi
Summary: This study found that B. bassiana and L. muscarium have good insecticidal effects on eggs and larvae of T. absoluta, and can be used as biological control agents in integrated pest management programs.
EGYPTIAN JOURNAL OF BIOLOGICAL PEST CONTROL
(2022)
Article
Agriculture, Multidisciplinary
S. Abolghasemi, K. Ahmadi, H. M. Takalozadeh
Summary: Tuta absoluta, a major pest of tomato crops, is predominantly controlled using chemical pesticides. However, there is growing emphasis on implementing environmentally safe strategies. This study demonstrates the high efficacy of Bacillus thuringiensis (Bt) in controlling T. absoluta and recommends Bt formulations as effective, environmentally friendly, and safe biopesticides. The toxicity of three chemical pesticides (Biolep, Abamectin, and Indoxacarb) is also evaluated, with the Bt formulation showing the highest efficacy compared to the chemical pesticides.
JOURNAL OF AGRICULTURAL SCIENCE AND TECHNOLOGY
(2023)
Article
Immunology
Gabriel Moura Mascarin, Natasha Sant'Anna Iwanicki, Jose Luis Ramirez, Italo Delalibera, Christopher A. Dunlap
Summary: Culturing Beauveria bassiana under high glucose concentrations and high aeration leads to a shift in fungal development towards blastospore production, with associated differential gene expression related to antioxidant, calcium transport, conidiation, and osmosensor-related genes. The highly expressed Hyd1 gene suggests involvement in spore coat assembly, and upregulation of HOG signaling pathway genes points to potential mechanisms behind blastospore development for industrial pest control applications.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2021)
Article
Biotechnology & Applied Microbiology
Birhan Aynalem, Diriba Muleta, Juan Venegas, Fassil Assefa
Summary: The study isolated 27 indigenous Beauveria strains from different types of soil in Ethiopia, with 12 of them screened based on their biological efficiency index (BEI). These isolates showed promising pathogenicity against Tuta absoluta, with five of them highly effective in laboratory bioassays and nearly monophyletic characters. Further field evaluation is needed for mass production.
JOURNAL OF GENETIC ENGINEERING AND BIOTECHNOLOGY
(2021)
Article
Multidisciplinary Sciences
Maryam Nouri-Aiin, Josef H. Gorres
Summary: Invasive species, including pheretimoid earthworms, have caused significant economic costs to the U.S. economy. The use of the commercial entomopathogenic fungal isolate BotaniGard (R) has shown effectiveness in reducing pheretimoid earthworm populations, with potential for further research to improve efficacy.
Article
Biotechnology & Applied Microbiology
Rayda Ben Ayed, Sezai Ercisli, Mohsen Hanana, Ahmed Rebai, Fabienne Moreau
Summary: The study analyzed the genetic diversity and population structure of 79 Mediterranean olive accessions using 15 genomic SSRs, revealing high levels of genetic diversity with 225 alleles and two sub-populations, one mainly composed of Spanish accessions.
BIOTECHNOLOGY LETTERS
(2022)
Article
Oncology
Hana Triki, Ken Declerck, Slim Charfi, Wala Ben Kridis, Kais Chaabane, Sawssan Ben Halima, Tahya Sellami, Ahmed Rebai, Wim Vanden Berghe, Boutheina Cherif
Summary: Our study reveals that CD155 promoter methylation is significantly associated with clinical-pathological features, prognosis, and immune infiltration in breast cancer. Low CD155 methylation rates are correlated with better prognosis, suggesting CD155 methylation profile may serve as a potential biomarker for breast cancer monitoring.
CANCER IMMUNOLOGY IMMUNOTHERAPY
(2022)
Letter
Hematology
Lamia M'barek, Salma Sakka, Fatma Megdiche, Nouha Farhat, Khadija Maalla, Dhaker Turki, Sawsan Feki, Ahmed Rebai, Mariem Dammak, Choumous Kallel, Chokri Mhiri
JOURNAL OF THROMBOSIS AND HAEMOSTASIS
(2022)
Letter
Infectious Diseases
Saba Gargouri, Nabil Abid, Hela Karray-Hakim, Ahmed Rebai
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
(2022)
Article
Biochemistry & Molecular Biology
Margaux Sala, Nathalie Allain, Melanie Moreau, Arnaud Jabouille, Elodie Henriet, Aya Abou-Hammoud, Arnaud Uguen, Sylvaine Di-Tommaso, Cyril Dourthe, Anne-Aurelie Raymond, Jean-William Dupuy, Emilie Gerard, Nathalie Dugot-Senant, Benoit Rousseau, Jean-Phillipe Merlio, Anne Pham-Ledart, Beatrice Vergier, Sophie Tartare-Deckert, Violaine Moreau, Frederic Saltel
Summary: Combined therapy with anti-BRAF plus anti-MEK is the first-line treatment for metastatic melanomas. However, tumor cell resistance is a major issue. This study shows that DDR2 inhibition can reduce AXL expression and stress fiber formation in resistant melanoma cells. Furthermore, DDR2 inhibition can control cell and tumor proliferation through the MAP kinase pathway.
Article
Cell Biology
Pauline Esteves, Benoit Allard, Alexis Celle, Isabelle Dupin, Elise Maurat, Olga Ousova, Matthieu Thumerel, Jean-William Dupuy, Thierry Leste-Lasserre, Roger Marthan, Pierre-Olivier Girodet, Thomas Trian, Patrick Berger
Summary: This study shows that asthmatic bronchial smooth muscle (BSM) cells enhance the replication of rhinovirus (RV) in bronchial epithelium through increased production of CCL20. Additionally, these asthmatic BSM cells downregulate the antiviral pathway PKR, leading to increased susceptibility of the bronchial epithelium to RV infection.
Article
Biochemistry & Molecular Biology
Bertrand Chauveau, Anne-Aurelie Raymond, Sylvaine Di Tommaso, Jonathan Visentin, Agathe Vermorel, Nathalie Dugot-Senant, Cyril Dourthe, Jean-William Dupuy, Julie Dechanet-Merville, Jean-Paul Duong Van Huyen, Marion Rabant, Lionel Couzi, Frederic Saltel, Pierre Merville
Summary: This study used proteomics to investigate the glomerular proteome modification in antibody-mediated rejection (ABMR) in kidney transplantation. It identified several proteins related to cellular stress, leukocyte activation, and tissue remodeling that were deregulated in ABMR. These findings may have implications for the diagnosis and treatment of ABMR.
Meeting Abstract
Biochemistry & Molecular Biology
Julie Lavie, Claude Lalou, Jean-William Dupuy, Walid Mahfouf, Agata Ars, Aurelie Lacaule, Hamid Reza Rezvani, Richard Patryk Ngondo, Giovanni Benard
BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
(2022)
Article
Multidisciplinary Sciences
Florian Alonso, Yuechao Dong, Ling Li, Tiya Jahjah, Jean-William Dupuy, Isabelle Fremaux, Dieter P. Reinhardt, Elisabeth Genot
Summary: Fibrillin-1 is a crucial factor in angiogenesis and its mutation disrupts blood vessel formation. Fibrillin-1 is found at the angiogenic front and regulates signaling pathways to promote endothelial cell growth. Administration of a C-terminal fragment of fibrillin-1 corrects the defects in mutant mice.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2023)
Article
Microbiology
Ayman Sabra, Nicolas Biteau, Jean-William Dupuy, Christophe Klopp, Thierry Noel, Karine Dementhon
Summary: In this study, it was found that a dpp3 Delta mutants of Candida lusitaniae were impaired in cell separation, pseudohyphal growth, and mating. The defective phenotypes were not restored even after wild-type DPP3 locus reconstruction, indicating the presence of an additional mutation, which was identified as MED15. The inactivation of MED15 was confirmed to be responsible for the defective phenotypes and its role in regulating hyphal growth, cell separation, and mating pathways was revealed.
Article
Microbiology
Amelie De Vallee, Jean-William Dupuy, Christine Moriscot, Benoit Gallet, Solene Vanderperre, Gaetan Guignard, Christine Rascle, Glen Calvar, Bastien Malbert, Francois-Xavier Gillet, Cindy Dieryckx, Mathias Choquer, Vincent Girard, Nathalie Poussereau, Christophe Bruel
Summary: This study identified and characterized extracellular vesicles produced by the plant necrotroph Botrytis cinerea. These vesicles contain proteins involved in various cellular processes and have the ability to target different cells. The study also demonstrated a positive effect of these vesicles on the growth of B. cinerea.
Article
Public, Environmental & Occupational Health
Ameni Chelly, Amal Bouzid, Fadoua Neifar, Ines Kammoun, Adel Tekari, Saber Masmoudi, Hamdi Chtourou, Ahmed Rebai
Summary: This study aimed to investigate the influence of physical activity on DNA methylation changes of the RANKL promoter region and assess the effect of aerobic and strength training on RANKL DNA methylation in Tunisian-North African adults. The results showed that active adults had significantly higher methylation levels in the RANKL promoter region compared to sedentary adults. After the intervention, both the trained and untrained groups exhibited increased methylation levels in the RANKL promoter region. The trained group also showed improvements in various physical parameters.
JOURNAL OF PHYSICAL ACTIVITY & HEALTH
(2023)
Article
Engineering, Biomedical
Leo Comperat, Lise Chagot, Sarah Massot, Marie-Laure Stachowicz, Nathalie Dusserre, Chantal Medina, Theo Desigaux, Jean-William Dupuy, Jean-Christophe Fricain, Hugo Oliveira
Summary: Bioinks derived from amnion and chorion have been developed and compared in terms of their extracellular matrix and growth factor compositions. These bioinks can sustain endothelial cell viability and promote vasculogenesis, holding significant potential for tissue engineering applications.
ADVANCED HEALTHCARE MATERIALS
(2023)
Article
Oncology
Farah Rahal, Caroline Capdevielle, Benoit Rousseau, Julien Izotte, Jean-William Dupuy, David Cappellen, Guillaume Chotard, Melissa Menard, Justine Charpentier, Vincent Jecko, Charline Caumont, Edouard Gimbert, Christophe F. Grosset, Martin Hagedorn
Summary: Background Diffuse Midline Glioma (DMG) is a highly aggressive pediatric tumor with limited treatment options. This study found that inhibiting EZH2 with GSK126 can induce expression of cholesterol metabolism-related proteins, and combined treatment with statins can significantly inhibit tumor growth.
NEURO-ONCOLOGY ADVANCES
(2022)
Article
Biochemistry & Molecular Biology
Rayda Ben Ayed, Fabienne Moreau, Hajer Ben Hlima, Ahmed Rebai, Sezai Ercisli, Narendra Kadoo, Mohsen Hanana, Amine Assouguem, Riaz Ullah, Essam A. Ali
Summary: The study identified genetic variations in the FAD2 gene in olive oil, which affect the fatty acid ratio and quality; Molecular modeling and docking experiments were used to explore the structure-function relationship of the FAD2 enzyme; Certain SNPs were found to have an impact on the saturated fatty acid content in olive oil.
COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL
(2022)