Mitochondrial replacement therapy: Cautiously replace the master manipulator

SCNT-Derived ESCs with Mismatched Mitochondria Trigger an Immune Response in Allogeneic Hosts

(2015) Tobias Deuse et al.   Cell Stem Cell

Polar Body Genome Transfer for Preventing the Transmission of Inherited Mitochondrial Diseases

(2014) Tian Wang et al.   CELL

Mitonuclear interactions: evolutionary consequences over multiple biological scales

(2014) J. N. Wolff et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Maternal age effect and severe germ-line bottleneck in the inheritance of human mitochondrial DNA

(2014) B. Rebolledo-Jaramillo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

From evolutionary bystander to master manipulator: the emerging roles for the mitochondrial genome as a modulator of nuclear gene expression

(2013) Martin P Horan et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Mitochondrial Replacement, Evolution, and the Clinic

(2013) K. Reinhardt et al.   SCIENCE

Mitochondria, maternal inheritance, and asymmetric fitness: Why males die younger

(2012) Jonci N. Wolff et al.   BIOESSAYS

Heteroplasmy of Mouse mtDNA Is Genetically Unstable and Results in Altered Behavior and Cognition

(2012) Mark S. Sharpley et al.   CELL

Towards germline gene therapy of inherited mitochondrial diseases

(2012) Masahito Tachibana et al.   NATURE

Pronuclear transfer in human embryos to prevent transmission of mitochondrial DNA disease

(2010) Lyndsey Craven et al.   NATURE