A genetic interaction between RAP1 and telomerase reveals an unanticipated role for RAP1 in telomere maintenance
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Title
A genetic interaction between RAP1 and telomerase reveals an unanticipated role for RAP1 in telomere maintenance
Authors
Keywords
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Journal
AGING CELL
Volume 15, Issue 6, Pages 1113-1125
Publisher
Wiley
Online
2016-09-02
DOI
10.1111/acel.12517
References
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Related references
Note: Only part of the references are listed.- Shelterin Protects Chromosome Ends by Compacting Telomeric Chromatin
- (2016) Jigar N. Bandaria et al. CELL
- TRF2-Mediated Control of Telomere DNA Topology as a Mechanism for Chromosome-End Protection
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- TRF2-RAP1 is required to protect telomeres from engaging in homologous recombination-mediated deletions and fusions
- (2016) Rekha Rai et al. Nature Communications
- TALEN Gene Knockouts Reveal No Requirement for the Conserved Human Shelterin Protein Rap1 in Telomere Protection and Length Regulation
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- The Hallmarks of Aging
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- Rap1 relocalization contributes to the chromatin-mediated gene expression profile and pace of cell senescence
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- Nontelomeric Role for Rap1 in Regulating Metabolism and Protecting against Obesity
- (2013) Frank Yeung et al. Cell Reports
- RAP1 Protects from Obesity through Its Extratelomeric Role Regulating Gene Expression
- (2013) Paula Martínez et al. Cell Reports
- Human Rap1 Interacts Directly with Telomeric DNA and Regulates TRF2 Localization at the Telomere
- (2012) N. Özlem Arat et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Human telomeric proteins occupy selective interstitial sites
- (2011) Dong Yang et al. CELL RESEARCH
- Role of shelterin in cancer and aging
- (2010) Paula Martínez et al. AGING CELL
- Telomere-independent Rap1 is an IKK adaptor and regulates NF-κB-dependent gene expression
- (2010) Hsiangling Teo et al. NATURE CELL BIOLOGY
- Mammalian Rap1 controls telomere function and gene expression through binding to telomeric and extratelomeric sites
- (2010) Paula Martinez et al. NATURE CELL BIOLOGY
- Loss of Rap1 Induces Telomere Recombination in the Absence of NHEJ or a DNA Damage Signal
- (2010) A. Sfeir et al. SCIENCE
- Telomeres Acquire Embryonic Stem Cell Characteristics in Induced Pluripotent Stem Cells
- (2009) Rosa M. Marion et al. Cell Stem Cell
- Human RAP1 inhibits non-homologous end joining at telomeres
- (2009) Jay Sarthy et al. EMBO JOURNAL
- Increased telomere fragility and fusions resulting from TRF1 deficiency lead to degenerative pathologies and increased cancer in mice
- (2009) P. Martinez et al. GENES & DEVELOPMENT
- MSH2 deficiency abolishes the anticancer and pro-aging activity of short telomeres
- (2008) Paula Martinez et al. AGING CELL
- The longest telomeres: a general signature of adult stem cell compartments
- (2008) I. Flores et al. GENES & DEVELOPMENT
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